Uncoupling protein 2 negatively regulates glucose-induced glucagon-like peptide 1 secretion

in Journal of Molecular Endocrinology
Authors:
Hongjie ZhangState Key Laboratory of Pharmaceutical Biotechnology, First Affiliated Hospital of Nanjing Medical University, School of Biological Sciences, Jiangsu Diabetes Center, Nanjing University, Nanjing, Jiangsu 210093, People's Republic of China
State Key Laboratory of Pharmaceutical Biotechnology, First Affiliated Hospital of Nanjing Medical University, School of Biological Sciences, Jiangsu Diabetes Center, Nanjing University, Nanjing, Jiangsu 210093, People's Republic of China

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Jing LiState Key Laboratory of Pharmaceutical Biotechnology, First Affiliated Hospital of Nanjing Medical University, School of Biological Sciences, Jiangsu Diabetes Center, Nanjing University, Nanjing, Jiangsu 210093, People's Republic of China

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Xiangying LiangState Key Laboratory of Pharmaceutical Biotechnology, First Affiliated Hospital of Nanjing Medical University, School of Biological Sciences, Jiangsu Diabetes Center, Nanjing University, Nanjing, Jiangsu 210093, People's Republic of China

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Yun LuoState Key Laboratory of Pharmaceutical Biotechnology, First Affiliated Hospital of Nanjing Medical University, School of Biological Sciences, Jiangsu Diabetes Center, Nanjing University, Nanjing, Jiangsu 210093, People's Republic of China

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Ke ZenState Key Laboratory of Pharmaceutical Biotechnology, First Affiliated Hospital of Nanjing Medical University, School of Biological Sciences, Jiangsu Diabetes Center, Nanjing University, Nanjing, Jiangsu 210093, People's Republic of China

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Chen-Yu ZhangState Key Laboratory of Pharmaceutical Biotechnology, First Affiliated Hospital of Nanjing Medical University, School of Biological Sciences, Jiangsu Diabetes Center, Nanjing University, Nanjing, Jiangsu 210093, People's Republic of China

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Free access

The authors and journal apologise for errors in the above paper, which appeared in volume 48 part 2, pages 151–158. The errors relate to the Materials and methods on page 152, and Figure 2 on page 154.

The error in the Materials and methods section on page 152 relates to some text under the ‘Animals and treatment’ section. The sentence ‘Following overnight fasting with free access to water, UCP2-deficient mice (n=20) and wild-type littermates (n=20) were given glucose (2 g/kg) by oral gavage and killed 15, 30, or 60 min thereafter’ omits the 90 min time point. The correct sentence should read ‘Following overnight fasting with free access to water, UCP2-deficient mice (n=20) and wild-type littermates (n=20) were given glucose (2 g/kg) by oral gavage and killed 15, 30, 60, or 90 min thereafter. UCP2-deficient mice (n=5) and wild-type mice (n=5) were used to assess glucose level and serum GLP-1 level without glucose treatment at 0 min’.

The error in Figure 2 on page 154 relates to the omission of the 90 minute time point from the figure artwork and legend. The correct Figure 2 is published in full below:

Figure 2
Figure 2

UCP2-deficient mice have higher serum GLP1 and lower plasma glucose levels. Blood glucose (left panel) and serum GLP1 (right panel) levels were assessed at time 0, 15, 30, 60, and 90 min after an oral glucose load (2.0 g/kg). UCP2-deficient mice (total number: 25, each time point n=5) and wild-type mice (total number: 25, each time point n=5), *P<0.05,**P<0.01,***P<0.001. A full colour version of this figure is available via http://dx.doi.org/10.1530/JME-11-0114e.

Citation: Journal of Molecular Endocrinology 55, 3; 10.1530/JME-11-0114e

 

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    UCP2-deficient mice have higher serum GLP1 and lower plasma glucose levels. Blood glucose (left panel) and serum GLP1 (right panel) levels were assessed at time 0, 15, 30, 60, and 90 min after an oral glucose load (2.0 g/kg). UCP2-deficient mice (total number: 25, each time point n=5) and wild-type mice (total number: 25, each time point n=5), *P<0.05,**P<0.01,***P<0.001. A full colour version of this figure is available via http://dx.doi.org/10.1530/JME-11-0114e.