Signalling mechanisms in progesterone-neurotransmitter interactions

in Journal of Molecular Endocrinology

The current and expanded view of transcriptional regulation by the steroid/thyroid superfamily of nuclear transcription factors integrates not only the hormone-dependent but also the hormone-independent cellular signaling mechanisms in physiology and reproduction. This effort has vastly been aided by the identification of steroid hormone receptors as transcriptional mediators of a variety of ligands, whose transcriptional response is dependent upon cross-talk with distinct signal transduction pathways, their recruitment of coregulators, alteration of chromatin structure and identification of specific interactive motifs within the receptors themselves. This review will provide a framework for the current concepts in the field of steroid hormone action as exemplified by our studies on progesterone receptor in female sexual behavior.


An official journal of

Society for Endocrinology

Index Card


Google Scholar

Related Articles



All Time Past Year Past 30 Days
Abstract Views 0 0 0
Full Text Views 95 95 9
PDF Downloads 48 48 8