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Introduction Thyroid hormone has long been known for its profound effects on the metabolic rate and cardiovascular function ( Magnus-Levy 1895 , Klein & Ojamaa 2001 ). This becomes most evident in hyperthyroidism, which is accompanied by an

Introduction Thyroid hormone (TH) is an important regulator of cardiovascular functions. This becomes evident in patients with hyperthyroidism presenting with tachycardia and cardiac hypertrophy, while bradycardia is a characteristic of

Introduction Thyroid hormone (3,5,3-tri-iodothyronine; T3) is an essential regulator of brain development. Supporting this notion, congenital hypothyroidism results in severe and irreversible mental retardation. Thyroid hormones in

Introduction Thyroid hormones (THs) are key in regulating energy homeostasis in both humans and rodents. Maintaining core body temperature is critical for homeothermic species and thermoregulation requires fine-tuned energy partitioning. Here

Introduction Thyroid hormone (3,3′,5-tri-iodothyronine; T 3 ) is an essential regulator of brain development, cell differentiation, and metabolic balance ( Yen 2001 ). Thyroid hormone regulates gene expression via binding to thyroid hormone

thyroid hormones (THs) positively regulate plasma levels of FN by unknown mechanisms. In addition, Baumgartner-Parzer et al. (1997) also showed that hyperthyroidism is associated with elevated plasma levels of FN. Thus, we focused our study on the

Introduction Thyroid hormone (3,5,3′-tri-iodothyronine; T3) is an essential regulator of brain development, congenital hypothyroidism resulting in severe and irreversible mental retardation. T3 directly activates gene expression by

Introduction Thyroid hormones influence plasma sex hormone-binding globulin (SHBG) levels under both normal and pathological conditions ( Anderson 1974 ) by altering the production of SHBG by hepatocytes ( Rosner et al . 1984 ). In addition, blood

Introduction Thyroid hormone is a pleiotropic hormone with widespread biological actions. The follicular cells of the thyroid gland produce predominantly thyroxine (T 4 ), but it is mainly 3,3′,5-tri-iodothyronine (T 3 ) that binds to the nuclear

Introduction Thyroid hormone (tri-iodothyronine, T 3 ) has long been recognized to play a key role in lipid metabolism and thermogenesis. However, the molecular mechanisms by which T 3 regulates lipid homeostasis have not been fully elucidated. The