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G Schuler, Y Dezhkam, L Tenbusch, MC Klymiuk, B Zimmer, and B Hoffmann

–epididymal compartment as the predominant source of SE in boars. In vitro experiments using purified Leydig cells suggested that they are the main producers of SE in the adult porcine testis ( Raeside & Renaud 1983 ). However, in our previous study, estrogen

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B Zimmer, L Tenbusch, M C Klymiuk, Y Dezhkam, and G Schuler

high concentrations in testicular tissue ( Ruokonen & Vihko 1974 ). This observation provides clear evidence for the testis as the predominant site where sulfonation takes place and observations from in vitro experiments using purified Leydig cells

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Maxime A Tremblay, Raifish E Mendoza-Villarroel, Nicholas M Robert, Francis Bergeron, and Jacques J Tremblay

regarding their expression and roles in the testis. So far, KLF4 has been immunolocalized to germ cells and Sertoli cells ( Behr & Kaestner 2002 , Godmann et al. 2008 ) whereas mRNA for Klf2 ( Anderson et al. 1995 ), Klf5 ( Sogawa et al. 1993

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Inge Seim, Amy A Lubik, Melanie L Lehman, Nadine Tomlinson, Eliza J Whiteside, Adrian C Herington, Colleen C Nelson, and Lisa K Chopin

RT-PCR with primers spanning the putative exons (in2c-ghrelin-ORF–F/R, Table 1 ). Briefly, for RT-PCR analyses, 2 μg total RNA from human testis and pancreas (FirstChoice, Ambion, Austin, TX, USA), and from the LNCaP prostate cancer cell line, were

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Ariane Zamoner, Kátia Padilha Barreto, Danilo Wilhelm Filho, Fabíola Sell, Viviane Mara Woehl, Fátima Costa Rodrigues Guma, Regina Pessoa-Pureur, and Fátima Regina Mena Barreto Silva

pivotal role in the regulation and maintenance of spermatogenesis and are the site of action of all hormonal influences modulating testis development. They also provide physical support to germ cells, form the blood–testis barrier, and secrete protein

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C Bois, C Delalande, M Nurmio, M Parvinen, L Zanatta, J Toppari, and S Carreau

the rat testis, several studies concerning aromatase expression at transcript ( Janulis et al . 1996 , Levallet & Carreau 1997 , Levallet et al . 1998 a , b , Bourguiba et al . 2003 a , b , Silandre et al . 2007 ) and protein levels ( Levallet

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Wing-Yee Lui and Will M Lee

, neighboring Sertoli cells closely associate with each other to form the blood–testis barrier (BTB) that is constituted by inter-Sertoli tight junctions (TJ) and basal ectoplasmic specializations (ES, an atypical adherens junction (AJ) type). The BTB is

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Nandana Das and T Rajendra Kumar

rodent bones. These observations have implications for understanding and treating bone loss in post-menopausal women. In the male, FSHRs are expressed on Sertoli cells in the testis. FSH regulates pre-pubertal proliferation and maturation of Sertoli cells

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H Santti, L Mikkonen, A Anand, S Hirvonen-Santti, J Toppari, M Panhuysen, F Vauti, M Perera, G Corte, W Wurst, O A Jänne, and J J Palvimo

abnormalities in chromosome condensation and segregation ( Mohr & Boswell 1999 , Betz et al. 2001 , Hari et al. 2001 ). PIASx is highly expressed in testis, and the protein can be detected in spermatogonia and pachytene spermatocytes up to stage

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Elisabeth Sambroni, Antoine D Rolland, Jean-Jacques Lareyre, and Florence Le Gac

study was aimed at identifying Fsh- and Lh-dependent genes expressed in trout testis using a transcriptomic approach to understand their respective effects during fish puberty. We demonstrated for the first time that Fsh and Lh have both common and