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Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy
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Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy
Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy
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adipogenesis. To this end, we used highly undifferentiated cells prepared from human adipose tissue, which present with the differentiation properties of mesenchymal stem cell – referred to here as adipose-derived mesenchymal stem cells (ADMSCs) – and murine 3T
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A Gutschow C Krone W 2010 Role of WNT-5a in the determination of human mesenchymal stem cells into preadipocytes . Journal of Biological Chemistry 285 6170 – 6178 . doi:10.1074/jbc.M109.054338 . Bilkovski R Schulte DM Oberhauser F
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Center for Stem Cell Research and Regenerative Medicine, Section of Hematology and Medical Oncology, Department of Pharmacology, Tulane University School of Medicine, 1430 Tulane Avenue, SL-99, New Orleans, Louisiana 70112, USA
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, Sargis et al . 2010 , Chamorro-Garcia et al . 2012 ). To date, no studies of BPA have been conducted in human adipose-tissue-derived stromal/stem cells (ASCs). In this study, ASCs were utilized to test whether BPA induces adipogenesis through the
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biparental and uniparental zygote to morula stages Smart-seq2 296 Differences between early embryonic stages progression and ES cells at different passages (Yan et al. 2013) Human zygote to blastocyst stage and embryonic stem cells (Tang et
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Centro de Investigaciones Medicas e Instituto de Investigaciones Sanitarias (CIMUS‐IDIS), Department of Cardiology, Department of Physiology, University of Santiago de Compostela (USC), C/Barcelona S/N, 15782 Santiago de Compostela, Spain
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injury but expressing differentiation markers A new population proposed in humans cKIT+/SOX2+/OCT4+/KLF4+/NANOG+ with in vivo and in vitro stem properties ( Rock et al . 2009 , Anversa et al . 2011 , Kajstura et al . 2011 ) Cardiac stem cells
Wellcome Trust Sanger Institute, Metabolic Research Laboratories, Wellcome Trust Genome Campus, Hinxton, UK
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Wellcome Trust Sanger Institute, Metabolic Research Laboratories, Wellcome Trust Genome Campus, Hinxton, UK
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( Lee et al . 2011 ). Human adipose-derived stem cells Several studies have been published investigating the potential of human multipotent adipose-derived stem cells (hMADS) as precursors for differentiation into brown or brite adipocytes. For instance
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diabetes treatment in animal models. Human embryonic stem cells (hESCs) were used to differentiate the pancreatic endoderm (PE) capable of treating diabetic mice ( Kroon et al . 2008 ). Pagliuca et al . (2014) have also demonstrated in a very recent
Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA
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Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA
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characteristics of trophoblast stem cells, their exact nature remains unclear. Recently, bona fide bovine TSCs have been isolated and maintained from bovine blastocysts on MEFS (or MEF-conditioned media) with the addition of human LIF, CHIR99021 (WNT activator
Biochemistry and
Internal Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
Department of Obstetrics and Gynecology, Tufts-New England Medical Center, Boston, MA 02111, USA
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Biochemistry and
Internal Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
Department of Obstetrics and Gynecology, Tufts-New England Medical Center, Boston, MA 02111, USA
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Biochemistry and
Internal Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
Department of Obstetrics and Gynecology, Tufts-New England Medical Center, Boston, MA 02111, USA
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Biochemistry and
Internal Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
Department of Obstetrics and Gynecology, Tufts-New England Medical Center, Boston, MA 02111, USA
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Biochemistry and
Internal Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
Department of Obstetrics and Gynecology, Tufts-New England Medical Center, Boston, MA 02111, USA
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Biochemistry and
Internal Medicine, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA
Department of Obstetrics and Gynecology, Tufts-New England Medical Center, Boston, MA 02111, USA
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and respond to these peptides ( Kempuraj et al. 2004 ). Here, we show for the first time that hCBMCs upregulate only CRH-R2 in response to IL-1, IL-4 and LPS. Materials and methods Recombinant human stem cell factor
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known for their role in the development and function of the nervous system ( Airaksinen & Saarma 2002 ) but GDNF is also important for the growth of the ureteric bud during kidney development ( Costantini & Shakya 2006 ) or spermatogonial stem cell