Filter

Refine by collections

Refine by access

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 1 - 10 of 252 items for :

  • dexamethasone x
  • Refine by access: All content x
Clear All
Kanchana Suksri Department of Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Search for other papers by Kanchana Suksri in
Google Scholar
PubMed Close
,
Namoiy Semprasert Department of Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Search for other papers by Namoiy Semprasert in
Google Scholar
PubMed Close
,
Mutita Junking Division of Molecular Medicine, Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Search for other papers by Mutita Junking in
Google Scholar
PubMed Close
,
Suchanoot Kutpruek Department of Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Search for other papers by Suchanoot Kutpruek in
Google Scholar
PubMed Close
,
Thawornchai Limjindaporn Department of Anatomy, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Search for other papers by Thawornchai Limjindaporn in
Google Scholar
PubMed Close
,
Pa-thai Yenchitsomanus Division of Molecular Medicine, Research Department, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Search for other papers by Pa-thai Yenchitsomanus in
Google Scholar
PubMed Close
, and
Suwattanee Kooptiwut Department of Physiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Search for other papers by Suwattanee Kooptiwut in
Google Scholar
PubMed Close

Introduction Glucocorticoids (GCs) are a group of steroid drugs that exert strong anti-inflammatory and immunosuppressive effects. The synthetic GCs include dexamethasone and prednisolone, which are currently in clinical use for the treatment

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-20-0238
Volume/Issue:
Volume 67: Issue 3
Restricted access
Ewa Harasim-Symbor Department of Physiology, Medical University of Bialystok, Białsytok, Podlaskie, Poland

Search for other papers by Ewa Harasim-Symbor in
Google Scholar
PubMed Close
,
Karolina Konstantynowicz-Nowicka Department of Physiology, Medical University of Bialystok, Białsytok, Podlaskie, Poland

Search for other papers by Karolina Konstantynowicz-Nowicka in
Google Scholar
PubMed Close
, and
Adrian Chabowski Department of Physiology, Medical University of Bialystok, Białsytok, Podlaskie, Poland

Search for other papers by Adrian Chabowski in
Google Scholar
PubMed Close

Introduction Dexamethasone (DEX) is one of the most commonly prescribed synthetic glucocorticoids with wide anti-inflammatory and immunosuppressive properties ( Overman et al . 2013 , Kumar et al . 2015 ). However, prolonged DEX treatment

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-16-0108
Volume/Issue:
Volume 57: Issue 4
Free access
Nathan Appanna Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK

Search for other papers by Nathan Appanna in
Google Scholar
PubMed Close
,
Hylton Gibson Department of Biochemistry, Stellenbosch University, Stellenbosch, Western Cape, South Africa

Search for other papers by Hylton Gibson in
Google Scholar
PubMed Close
,
Elena Gangitano Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK
Department of Experimental Medicine, Sapienza University of Rome, Rome, Lazio, Italy

Search for other papers by Elena Gangitano in
Google Scholar
PubMed Close
,
Niall J Dempster Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK

Search for other papers by Niall J Dempster in
Google Scholar
PubMed Close
,
Karen Morris Biochemistry Department, Manchester University NHS Trust, Manchester Academic Health Science Centre, Manchester, Greater Manchester, UK

Search for other papers by Karen Morris in
Google Scholar
PubMed Close
,
Sherly George Biochemistry Department, Manchester University NHS Trust, Manchester Academic Health Science Centre, Manchester, Greater Manchester, UK

Search for other papers by Sherly George in
Google Scholar
PubMed Close
,
Anastasia Arvaniti Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK
Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, Oxfordshire, UK

Search for other papers by Anastasia Arvaniti in
Google Scholar
PubMed Close
,
Laura L Gathercole Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK
Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, Oxfordshire, UK

Search for other papers by Laura L Gathercole in
Google Scholar
PubMed Close
,
Brian Keevil Biochemistry Department, Manchester University NHS Trust, Manchester Academic Health Science Centre, Manchester, Greater Manchester, UK

Search for other papers by Brian Keevil in
Google Scholar
PubMed Close
,
Trevor M Penning Center of Excellence in Environmental Toxicology and Department of Systems Pharmacology & Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

Search for other papers by Trevor M Penning in
Google Scholar
PubMed Close
,
Karl-Heinz Storbeck Department of Biochemistry, Stellenbosch University, Stellenbosch, Western Cape, South Africa

Search for other papers by Karl-Heinz Storbeck in
Google Scholar
PubMed Close
,
Jeremy W Tomlinson Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK

Search for other papers by Jeremy W Tomlinson in
Google Scholar
PubMed Close
, and
Nikolaos Nikolaou Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, Oxfordshire, UK

Search for other papers by Nikolaos Nikolaou in
Google Scholar
PubMed Close

. 2019 a ). Crucially, AKR1D1-002 is also implicated in drug metabolism, as it metabolises the synthetic glucocorticoids prednisolone and dexamethasone, with downstream decreases in glucocorticoid receptor activation ( Nikolaou et al. 2020 ). The

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-20-0160
Volume/Issue:
Volume 66: Issue 3
Open access
Lijuan Yin Department of Pathophysiology, The Second Military Medical University, Shanghai, China

Search for other papers by Lijuan Yin in
Google Scholar
PubMed Close
,
Fang Fang Department of Obstetrics and Gynecology, Changhai Hospital, The Second Military Medical University, Shanghai, China

Search for other papers by Fang Fang in
Google Scholar
PubMed Close
,
Xinglei Song Department of Pathophysiology, The Second Military Medical University, Shanghai, China

Search for other papers by Xinglei Song in
Google Scholar
PubMed Close
,
Yan Wang Department of Pathophysiology, The Second Military Medical University, Shanghai, China

Search for other papers by Yan Wang in
Google Scholar
PubMed Close
,
Gaoxiang Huang Department of Pathophysiology, The Second Military Medical University, Shanghai, China

Search for other papers by Gaoxiang Huang in
Google Scholar
PubMed Close
,
Jie Su Department of Pathophysiology, The Second Military Medical University, Shanghai, China

Search for other papers by Jie Su in
Google Scholar
PubMed Close
,
Ning Hui Department of Obstetrics and Gynecology, Changhai Hospital, The Second Military Medical University, Shanghai, China

Search for other papers by Ning Hui in
Google Scholar
PubMed Close
, and
Jian Lu Department of Pathophysiology, The Second Military Medical University, Shanghai, China

Search for other papers by Jian Lu in
Google Scholar
PubMed Close

signaling molecules and intracellular pathways. Our previous works demonstrated that treatment of human ovarian cancer cells with dexamethasone (DEX), a synthetic GC, significantly increases cellular adhesion to ECM and their resistance to apoptosis induced

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-15-0142
Volume/Issue:
Volume 57: Issue 1
Free access
Eugenia Mata-Greenwood Divisions of Pharmacology and Physiology, Department of Basic Sciences, School of Medicine, Center for Perinatal Biology, Medical Center, Loma Linda University, Room A572, 11234 Anderson Street, Loma Linda, CA 92350, USA

Search for other papers by Eugenia Mata-Greenwood in
Google Scholar
PubMed Close
,
P Naomi Jackson Divisions of Pharmacology and Physiology, Department of Basic Sciences, School of Medicine, Center for Perinatal Biology, Medical Center, Loma Linda University, Room A572, 11234 Anderson Street, Loma Linda, CA 92350, USA

Search for other papers by P Naomi Jackson in
Google Scholar
PubMed Close
,
William J Pearce Divisions of Pharmacology and Physiology, Department of Basic Sciences, School of Medicine, Center for Perinatal Biology, Medical Center, Loma Linda University, Room A572, 11234 Anderson Street, Loma Linda, CA 92350, USA

Search for other papers by William J Pearce in
Google Scholar
PubMed Close
, and
Lubo Zhang Divisions of Pharmacology and Physiology, Department of Basic Sciences, School of Medicine, Center for Perinatal Biology, Medical Center, Loma Linda University, Room A572, 11234 Anderson Street, Loma Linda, CA 92350, USA

Search for other papers by Lubo Zhang in
Google Scholar
PubMed Close

( Kassel & Herrlich 2007 , Biddie et al . 2012 ). Previously, we have shown that human endothelial sensitivity to dexamethasone (DEX) varied according to the levels of GRα protein degradation ( Mata-Greenwood et al . 2013 ). Human umbilical vein

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-15-0124
Volume/Issue:
Volume 55: Issue 2
Open access
N Hoggard
Search for other papers by N Hoggard in
Google Scholar
PubMed Close
,
M Cruickshank
Search for other papers by M Cruickshank in
Google Scholar
PubMed Close
,
K M Moar
Search for other papers by K M Moar in
Google Scholar
PubMed Close
,
P Barrett
Search for other papers by P Barrett in
Google Scholar
PubMed Close
,
S Bashir
Search for other papers by S Bashir in
Google Scholar
PubMed Close
, and
J D B Miller Rowett Institute of Nutrition and Health, Department of Surgery, Aberdeen Centre for Energy Regulation and Obesity (ACERO), University of Aberdeen, Bucksburn, Aberdeen, Scotland AB21 9SB, UK

Search for other papers by J D B Miller in
Google Scholar
PubMed Close

(Sigma). Differentiation was initiated 24 h after confluence by incubation for 2 days in a culture medium containing 0.25 μM dexamethasone (Dex), 0.5 mM 3-isobutyl-1-methyl-xanthine and 5 μg/ml insulin (Sigma). This was followed by maintenance in feeding

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-09-0046
Volume/Issue:
Volume 43: Issue 4
Free access
Shambhunath Bose Proteonik Inc., Gyeonggi Bio Center, 12 Floor, 864-1 Iui-Dong, Yeongtong-Gu, Suwon City 443-766, South Korea
Micro Biochip Center, Hanyang University, Ansan City 425-170, South Korea

Search for other papers by Shambhunath Bose in
Google Scholar
PubMed Close
,
M Abul Farah Proteonik Inc., Gyeonggi Bio Center, 12 Floor, 864-1 Iui-Dong, Yeongtong-Gu, Suwon City 443-766, South Korea
Micro Biochip Center, Hanyang University, Ansan City 425-170, South Korea

Search for other papers by M Abul Farah in
Google Scholar
PubMed Close
,
Ho-Chul Jung Proteonik Inc., Gyeonggi Bio Center, 12 Floor, 864-1 Iui-Dong, Yeongtong-Gu, Suwon City 443-766, South Korea
Micro Biochip Center, Hanyang University, Ansan City 425-170, South Korea

Search for other papers by Ho-Chul Jung in
Google Scholar
PubMed Close
,
Jeong-Heon Lee Proteonik Inc., Gyeonggi Bio Center, 12 Floor, 864-1 Iui-Dong, Yeongtong-Gu, Suwon City 443-766, South Korea
Micro Biochip Center, Hanyang University, Ansan City 425-170, South Korea

Search for other papers by Jeong-Heon Lee in
Google Scholar
PubMed Close
, and
Yangsun Kim Proteonik Inc., Gyeonggi Bio Center, 12 Floor, 864-1 Iui-Dong, Yeongtong-Gu, Suwon City 443-766, South Korea
Micro Biochip Center, Hanyang University, Ansan City 425-170, South Korea

Search for other papers by Yangsun Kim in
Google Scholar
PubMed Close

receiving an exposure to BMOV for 18 h and a brief insulin treatment for 15 min. Consequently, we have also checked whether treatment of dexamethasone which has been shown to increase the cellular content of IR in 3T3 fibroblasts and IM9 cells ( Fantus et

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.02186
Volume/Issue:
Volume 38: Issue 6
Free access
Z G Song Departments of, Animal Science, Food Science, Shandong Agricultural University, Taian, Shandong 271018, People's Republic of China

Search for other papers by Z G Song in
Google Scholar
PubMed Close
,
X H Zhang Departments of, Animal Science, Food Science, Shandong Agricultural University, Taian, Shandong 271018, People's Republic of China

Search for other papers by X H Zhang in
Google Scholar
PubMed Close
,
L X Zhu Departments of, Animal Science, Food Science, Shandong Agricultural University, Taian, Shandong 271018, People's Republic of China

Search for other papers by L X Zhu in
Google Scholar
PubMed Close
,
H C Jiao Departments of, Animal Science, Food Science, Shandong Agricultural University, Taian, Shandong 271018, People's Republic of China

Search for other papers by H C Jiao in
Google Scholar
PubMed Close
, and
H Lin Departments of, Animal Science, Food Science, Shandong Agricultural University, Taian, Shandong 271018, People's Republic of China

Search for other papers by H Lin in
Google Scholar
PubMed Close

dexamethasone (DEX)-induced augmented proteolysis ( Sacheck et al . 2004 ). Compared with mammals, the insulin cascade appears to be refractory in the muscle tissue of chickens ( Dupont et al . 2004 , 2008 ). However, the PI3K/AKT/MTOR pathway in chicken

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-10-0162
Volume/Issue:
Volume 46: Issue 3
Free access
Michael Wöltje Interdisciplinary Center for Clinical Research (IZKF) ‘BIOMAT’, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany
Division of Nephrology and Immunology, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany

Search for other papers by Michael Wöltje in
Google Scholar
PubMed Close
,
Beate Tschöke Interdisciplinary Center for Clinical Research (IZKF) ‘BIOMAT’, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany
Division of Nephrology and Immunology, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany

Search for other papers by Beate Tschöke in
Google Scholar
PubMed Close
,
Verena von Bülow Interdisciplinary Center for Clinical Research (IZKF) ‘BIOMAT’, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany
Division of Nephrology and Immunology, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany

Search for other papers by Verena von Bülow in
Google Scholar
PubMed Close
,
Ralf Westenfeld Interdisciplinary Center for Clinical Research (IZKF) ‘BIOMAT’, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany
Division of Nephrology and Immunology, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany

Search for other papers by Ralf Westenfeld in
Google Scholar
PubMed Close
,
Bernd Denecke Interdisciplinary Center for Clinical Research (IZKF) ‘BIOMAT’, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany
Division of Nephrology and Immunology, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany

Search for other papers by Bernd Denecke in
Google Scholar
PubMed Close
,
Steffen Gräber Interdisciplinary Center for Clinical Research (IZKF) ‘BIOMAT’, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany
Division of Nephrology and Immunology, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany

Search for other papers by Steffen Gräber in
Google Scholar
PubMed Close
, and
Willi Jahnen-Dechent Interdisciplinary Center for Clinical Research (IZKF) ‘BIOMAT’, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany
Division of Nephrology and Immunology, RWTH Aachen University Hospital, Pauwelsstr. 30, D-52074 Aachen, Germany

Search for other papers by Willi Jahnen-Dechent in
Google Scholar
PubMed Close

of inflammation. Our working hypothesis was that glucocorticoids may enhance Ahsg expression on the transcriptional level and may therefore be useful in up-regulating Ahsg during inflammation. We report that dexamethasone up-regulates Ahsg gene

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.02001
Volume/Issue:
Volume 36: Issue 2
Free access
A Cote-Vélez Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, AP 510-3, Cuernavaca, Mor. 62250, México

Search for other papers by A Cote-Vélez in
Google Scholar
PubMed Close
,
L Pérez-Martínez Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, AP 510-3, Cuernavaca, Mor. 62250, México

Search for other papers by L Pérez-Martínez in
Google Scholar
PubMed Close
,
M Y Díaz-Gallardo Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, AP 510-3, Cuernavaca, Mor. 62250, México

Search for other papers by M Y Díaz-Gallardo in
Google Scholar
PubMed Close
,
C Pérez-Monter Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, AP 510-3, Cuernavaca, Mor. 62250, México

Search for other papers by C Pérez-Monter in
Google Scholar
PubMed Close
,
A Carreón-Rodríguez Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, AP 510-3, Cuernavaca, Mor. 62250, México

Search for other papers by A Carreón-Rodríguez in
Google Scholar
PubMed Close
,
J-L Charli Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, AP 510-3, Cuernavaca, Mor. 62250, México

Search for other papers by J-L Charli in
Google Scholar
PubMed Close
, and
P Joseph-Bravo Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, AP 510-3, Cuernavaca, Mor. 62250, México

Search for other papers by P Joseph-Bravo in
Google Scholar
PubMed Close

effect of long-term treatment (days) with dexamethasone (dex) on proTRH mRNA levels was first described in CA77 cells ( Tavianini et al. 1989 ), and later in rat anterior pituitary or in diencephalic primary cultures ( Bruhn et al. 1994 , Luo et al

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.01634
Volume/Issue:
Volume 34: Issue 1
Free access