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Liting Wu Department of Endocrinology and Metabolism, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Li Xiong Department of Endocrinology and Metabolism, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Jin Li Department of Endocrinology and Metabolism, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
Department of Geriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Zishan Peng Department of Endocrinology and Metabolism, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Luyao Zhang Department of Endocrinology and Metabolism, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Peijie Shi Department of Endocrinology and Metabolism, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Yingying Gong Department of Endocrinology and Metabolism, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
Department of Geriatrics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Haipeng Xiao Department of Endocrinology and Metabolism, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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indicates that small RNAs (miRNA) and long non-coding RNAs play key roles in regulating β-cell functions ( Guay et al. 2012 , Nesca et al. 2013 , Motterle et al. 2017 ). However, experimental data linking circular RNAs (circRNAs) to β-cell functions

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-20-0079
Volume/Issue:
Volume 65: Issue 4
Open access
Chang-Jiang Wang Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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Fei Gao Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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Yi-Jie Huang Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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Dong-Xu Han Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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Yi Zheng Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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Wen-Hua Wang Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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Hao Jiang Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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Yan Gao Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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Bao Yuan Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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Jia-Bao Zhang Department of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun, Jilin, China

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maintain energy homeostasis ( Sun et al. 2006 , Liu et al. 2017 ). Consequently, it is crucial to further address the molecular mechanisms involved in FSH regulation. Circular RNAs (circRNAs), a novel class of noncoding RNAs, have attracted great

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-20-0036
Volume/Issue:
Volume 65: Issue 4
Restricted access
Junling Wang Gynecologic Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

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Hongyan Zhang Gynecologic Department, Hainan Traditional Chinese Medicine Hospital, Haikou, China

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Yue Cao Science and technology department, Guangzhou University of Chinese Medicine, Guangzhou, China

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Irene Ma Gynecologic Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

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Xuefang Liang Gynecologic Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

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Dongfang Xiang Gynecologic Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

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(BMSCs) in postmenopausal OP by targeting miR-135a-5p ( Wang et al. 2019 ). Additionally, emerging evidence indicates that circular RNAs (circRNAs), such as circRNA_0016624 and circRNA_0048211, might play a significant role in the progression of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-23-0140
Volume/Issue:
Volume 73: Issue 1
Restricted access
Jiayu Jin Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China

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Xinhong Wang Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China

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Xiuling Zhi Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China

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Dan Meng Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China

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metformin-induced activation of DICER, a central enzyme involved in miRNA processing, may also explain why metformin administration can rescue endothelial dysfunction ( Noren Hooten et al. 2016 ). Circular RNAs Circular RNAs (cirRNAs) are a

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-19-0170
Volume/Issue:
Volume 63: Issue 4
Free access
Suzy Markossian Institut de Génomique Fonctionnelle de Lyon, Université de Lyon, CNRS, INRA, École Normale Supérieure de Lyon, Lyon Cedex 07, France

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Frédéric Flamant Institut de Génomique Fonctionnelle de Lyon, Université de Lyon, CNRS, INRA, École Normale Supérieure de Lyon, Lyon Cedex 07, France

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H Isotani A Ikawa M 2013 Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA . Scientific Reports 3 3355 . McDonald JI Celik H Rois LE Fishberger G Fowler T

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-15-0305
Volume/Issue:
Volume 57: Issue 2
Free access
Rachel C Quilang Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK

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Sylvia Lui Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
St. Mary’s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK

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Karen Forbes Leeds Institute of Cardiovascular and Metabolic Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK
Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK

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circular RNA (circRNA) actions ( Ding et al. 2021 , Xiao et al. 2021 , Zhang et al. 2021 ). While miR-758-3p do not influence proliferation in the placenta, migration and invasion are also key features of normal placentation ( Knofler & Pollheimer

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-21-0175
Volume/Issue:
Volume 68: Issue 2
Open access
Hannah E Lapp Department of Psychology, University of Massachusetts Boston, Boston, Massachusetts, USA

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Andrew A Bartlett Department of Psychology, University of Massachusetts Boston, Boston, Massachusetts, USA

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Richard G Hunter Department of Psychology, University of Massachusetts Boston, Boston, Massachusetts, USA

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). Because of their endosymbiotic origin, mitochondria are the only metazoan organelles that have their own genome (the chloroplast in plants being the other significant eukaryotic organelle with its own genome). The circular mitochondrial genome has been

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-18-0152
Volume/Issue:
Volume 62: Issue 2
Free access
Yewei Xing
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C Richard Parker Departments of Physiology and Surgery, Department of Obstetrics and Gynecology, Medical College of Georgia, 1120 15th Street, Augusta, Georgia 30912, USA

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Michael Edwards
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William E Rainey
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overnight incubation followed by 48-h treatment with or without ACTH (10 nM; Organon, Bedford, OH, USA). The cells were lysed for RNA isolation, and the media were collected for steroid assays as described below. RNA isolation Total RNA was extracted from

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-10-0006
Volume/Issue:
Volume 45: Issue 1
Free access
Salman Azhar Geriatric Research, Education and Clinical Center, VA Palo Alto Health Care System, Palo Alto, California, USA
Division of Endocrinology, Gerontology and Metabolism, Stanford University, Stanford University, Stanford, California, USA
Stanford Diabetes Research Center, Stanford, California, USA

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Dachuan Dong Geriatric Research, Education and Clinical Center, VA Palo Alto Health Care System, Palo Alto, California, USA
Division of Endocrinology, Gerontology and Metabolism, Stanford University, Stanford University, Stanford, California, USA

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Wen-Jun Shen Geriatric Research, Education and Clinical Center, VA Palo Alto Health Care System, Palo Alto, California, USA
Division of Endocrinology, Gerontology and Metabolism, Stanford University, Stanford University, Stanford, California, USA

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Zhigang Hu Jiangsu Key Laboratory for Molecular and Medical Biotechnology and College of Life Science, Nanjing Normal University, Nanjing, China

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Fredric B Kraemer Geriatric Research, Education and Clinical Center, VA Palo Alto Health Care System, Palo Alto, California, USA
Division of Endocrinology, Gerontology and Metabolism, Stanford University, Stanford University, Stanford, California, USA
Stanford Diabetes Research Center, Stanford, California, USA

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, natural antisense transcripts, pseudogenes and circular RNAs (circRNAs), ribozymes, ribosomal RNAs (rRNAs), transfer RNAs (tRNAs), small nucleolar RNAs (snRNAs), Piwi-associated RNAs (piRNAs), small nuclear RNAs (snoRNAs), telomere-associated RNAs (TERC

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-19-0105
Volume/Issue:
Volume 64: Issue 1
Free access
Kazue Nagasawa Faculty of Biosciences and Aquaculture, Department of Zoology, University of Nordland, 8049 Bodø, Norway

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Christopher Presslauer Faculty of Biosciences and Aquaculture, Department of Zoology, University of Nordland, 8049 Bodø, Norway

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Lech Kirtiklis Faculty of Biosciences and Aquaculture, Department of Zoology, University of Nordland, 8049 Bodø, Norway
Faculty of Biosciences and Aquaculture, Department of Zoology, University of Nordland, 8049 Bodø, Norway

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Igor Babiak Faculty of Biosciences and Aquaculture, Department of Zoology, University of Nordland, 8049 Bodø, Norway

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Jorge M O Fernandes Faculty of Biosciences and Aquaculture, Department of Zoology, University of Nordland, 8049 Bodø, Norway

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at −80 °C for subsequent RNA extraction. For histological observations and quantitative real-time PCR (qPCR) analysis, testes ( n =5) and ovaries ( n =5) were sampled from individual fish at each sampling time point, fixed with 4% paraformaldehyde

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-13-0187
Volume/Issue:
Volume 52: Issue 3
Free access