trophoblasts and ESCs. Adiponectin is a 30 kDa cytokine, predominantly produced by adipose tissue ( Kern et al. 2003 ). Adiponectin exerts its action via two specific receptors (ADIPOR1 and ADIPOR2) containing seven transmembrane domains but which are
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Fabien Duval, Esther Dos Santos, Hadia Moindjie, Valérie Serazin, Nelly Swierkowski-Blanchard, François Vialard, and Marie-Noëlle Dieudonné
Fabien Duval, Esther Dos Santos, Benoît Maury, Valérie Serazin, Khadija Fathallah, François Vialard, and Marie-Noëlle Dieudonné
process is called glycophagy ( Kaur & Debnath 2015 ). It can be hypothesized that endometrial glycogen follows this pathway and thus provides placental cells and/or the fetus with glucose. Adiponectin is a 30 kDa protein that is described as an insulin
Naoki Hattori, Ayato Yamada, Shunya Nakatsuji, Takeshi Matsuda, Norito Nishiyama, and Akira Shimatsu
Introduction Adipocytes produce several types of cytokines, termed ‘adipocytokines’, which include adiponectin and leptin ( Tilg & Moschen 2006 ). Adiponectin suppresses hepatic gluconeogenesis by inhibiting the related gene expression
Hui Wang, Wenjing Wu, Jun Duan, Ming Ma, Wei Kong, Yuannan Ke, Gang Li, and Jingang Zheng
a potential benefit for the development of pharmacological therapies for heart injuries induced by acute MI. Adiponectin (APN) is an adipocyte-derived cytokine normally present in human plasma at concentrations of 0.5–30 µg/mL, comprising about 0
Toshihiro Kobayashi, Hitomi Imachi, Kensaku Fukunaga, Jingya Lyu, Seisuke Sato, Takanobu Saheki, Tomohiro Ibata, Mari Matsumoto, Salimah B Japar, and Koji Murao
that contribute to the regulation of energy metabolism in the body. Adiponectin (APN), an adipokine, is an adipocyte-derived vasoactive peptide with anti-inflammatory and insulin-sensitizing peptides. A number of clinical trials have shown that subjects
Vivian Vu, Phuong Bui, Megumi Eguchi, Aimin Xu, and Gary Sweeney
Introduction The beneficial effects of adiponectin on peripheral metabolism are now well characterized ( Yamauchi & Kadowaki 2008 , Matsuzawa 2010 , Dadson et al . 2011 ). Adiponectin targets multiple metabolic tissues including skeletal muscle
Zhi Zhang, Fang Wang, Bing-jian Wang, Guang Chu, Qunan Cao, Bao-Gui Sun, and Qiu-Yan Dai
artery endothelial cells and smooth muscle cells ( Kang et al . 2000 , Knudson et al . 2005 ). However, the role of leptin in vascular ECM remodelling remains unclear. Unlike leptin, which has profibrogenic effects, adiponectin, a 30-kDa adipokine, is
Penny Ahlstrom, Esther Rai, Suharto Chakma, Hee Ho Cho, Palanivel Rengasamy, and Gary Sweeney
adiponectin with diabetes and skeletal muscle insulin resistance exists in humans and animal models ( Stern et al. 2016 ). Adiponectin is now established as an anti-diabetic hormone ( Cheng et al. 2014 ). Muscle is one important target tissue of
Gabriela Capllonch-Amer, Isabel Lladó, Ana M Proenza, Francisco J García-Palmer, and Magdalena Gianotti
tissue (WAT) is more than a simple fat deposit, as it is an endocrine organ that contributes to energy homeostasis mechanisms by releasing proteins that are commonly referred to as adipokines ( Harwood 2012 , Henry et al . 2012 ). Adiponectin is an
Philip W Peake, Jaquelyne T Hughes, Yvonne Shen, and John A Charlesworth
Introduction Adiponectin is an adipocyte-specific protein related in structure to the complement component Clq. As with C1q, it self-associates into trimers, as well as higher molecular weight isoforms. Depending upon the assay
