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Thomas Svava Nielsen, Niels Jessen, Jens Otto L Jørgensen, Niels Møller and Sten Lund

lipolysis, three lipases act in sequence with the concomitant release of one FFA in each step ( Fig. 1 ); adipose TG lipase (ATGL) converts TG to DG and is the rate-limiting enzyme in the lipolytic pathway ( Zimmermann et al . 2004 ). DG is hydrolyzed to MG

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Hui Juan Zhu, Hui Pan, Xu Zhe Zhang, Nai Shi Li, Lin Jie Wang, Hong Bo Yang and Feng Ying Gong

)), lipid-metabolism-related enzyme genes ( Acc1 , Fas , Dgat , glycerol-3-phosphate dehydrogenase ( Gpdh ), acyl-CoA synthetase long-chain family member1 ( Acs1 ), carnitine palmitoyltransferase1 ( Cpt1 ), adipose TG lipase ( Atgl ) and Hsl ), and

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Tingting Zhang, Jinhan He, Chong Xu, Luxia Zu, Hongfeng Jiang, Shenshen Pu, Xiaohui Guo and Guoheng Xu

and adipose triglyceride lipase (ATGL; Londos et al . 1999 , Schweiger et al . 2006 ). Therefore, we investigated the influence of metformin on total activity of adipocyte lipases. Isolated adipocytes were preincubated for 12 h with or without 500

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Fei Xiao, Ying Du, Ziquan Lv, Shanghai Chen, Jianmin Zhu, Hongguang Sheng and Feifan Guo

control for normalization. The primers for Atgl were as follows: sense 5′-GTGAAGCAGGTGCCAACATTATTG-3′, antisense 5′-AAACACGAGTCAGGGAGATGCC-3′. Statistics All data are expressed as mean ±  s.e.m . Significant differences between (−) Phe, (−) Thr

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Rebecca H Ritchie, Eser J Zerenturk, Darnel Prakoso and Anna C Calkin

metabolism. ATGL, adipose triglyceride lipase; CD36, cluster of differentiation 36; CGI-58, comparative gene identification 58; DAG, diacylglycerol; DGAT, diacylglycerol acyltransferase; FA, fatty acid; FABP, fatty acid binding protein; FAT, fatty acid

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Yueting Dong, Zhiye Xu, Ziyi Zhang, Xueyao Yin, Xihua Lin, Hong Li and Fenping Zheng

incubated with primary antibodies (diluted 1:1000) including anti-rabbit cleaved caspase 3 and 9, cleaved PARP, phosphorylated HSL (s660, s565 and s563), HSL, ATGL, perilipin (PLIN1), phosphorylated Akt, Akt, GLUT4 (plasma membrane protein) and β-actin (Cell

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Marina R Pulido, Yoana Rabanal-Ruiz, Farid Almabouada, Alberto Díaz-Ruiz, María A Burrell, María J Vázquez, Justo P Castaño, Rhonda D Kineman, Raúl M Luque, Carlos Diéguez, Rafael Vázquez-Martínez and María M Malagón

, visceral fat is more responsive to fasting conditions than subcutaneous fat with regard to the induction of the lipolytic enzymes, hormone-sensitive lipase (HSL; Akesson et al . 2003 ), and adipose triglyceride lipase (ATGL; Palou et al . 2010 ). In

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C Attané, D Daviaud, C Dray, R Dusaulcy, M Masseboeuf, D Prévot, C Carpéné, I Castan-Laurell and P Valet

M Perry RL Ceddia RB 2009 Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL . Journal of Lipid Research 50 704 – 715 . doi:10.1194/jlr.M800480-JLR200

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Haihua Yang and Linghai Yang

-dependent phosphorylation of lipid droplet-associated protein perilipin A, hormone-sensitive lipase (HSL), and adipose triglyceride lipase (ATGL). Insulin promotes glucose uptake and de novo lipogenesis, and inhibits lipolysis by activating PDE3B to suppress cAMP

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Eva Tudurí, Monica Imbernon, Rene Javier Hernández-Bautista, Marta Tojo, Johan Fernø, Carlos Diéguez and Rubén Nogueiras

Diaz-Arteaga et al . (2012) Sprague–Dawley rats O-1602 Agonist 13, >30,000, >30,000 nM 0.1 mg/kg/day, i.p. Unchanged food intake and body weight gain, increased fat mass, decreased WAT ATGL and increased WAT IL-6 mRNA levels Diaz