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Angelina Rafaela Debortoli, Wender do Nascimento Rouver, Nathalie Tristão Banhos Delgado, Vinicius Mengal, Erick Roberto Gonçalves Claudio, Laena Pernomian, Lusiane Maria Bendhack, Margareth Ribeiro Moysés, and Roger Lyrio dos Santos

test was used to analyse coronary protein expression and dihydroethidium fluorescence. CPP data and vascular reactivity to G-1 were analysed by two-way analysis of variance (ANOVA), followed by the Bonferroni post hoc test. Each P value is adjusted

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Jéssyca Aparecida Soares Giesen, Wender do Nascimento Rouver, Eduardo Damasceno Costa, Virgínia Soares Lemos, and Roger Lyrio dos Santos

). Vascular reactivity: studies in isolated hearts The isolated hearts study was performed as previously described ( Debortoli et al. 2017 ). The animals were anesthetized with ketamine (70 mg/kg, i.p.) and xylazine (10 mg/kg, i.p.). The thoracic cavity

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Juan Carlos Arapa-Diaz, Wender do Nascimento Rouver, Jéssyca Aparecida Soares Giesen, Marcela Daruge Grando, Lusiane Maria Bendhack, and Roger Lyrio dos Santos

( Svartberg et al. 2004 ), suggesting that the testosterone/hypertension relationship is not completely clear, particularly as to its influence in coronary vascular reactivity. Classical (genomic or nuclear) actions of testosterone are represented by the

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Sogol Gachkar, Sebastian Nock, Cathleen Geissler, Rebecca Oelkrug, Kornelia Johann, Julia Resch, Awahan Rahman, Anders Arner, Henriette Kirchner, and Jens Mittag

Iwata T Mochizuki T Kogo H 2000 Changes in vascular reactivity induced by acute hyperthyroidism in isolated rat aortae . General Pharmacology 34 429 – 434 . ( ) 11483292 10.1016/S0306

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Yanxia Tang and GuoDong Li

A . Totowa, NJ : Humana Press, Inc . Karasu C Altan VM 1993 The role of endothelial cells on the alterations in vascular reactivity induced by insulin-dependent diabetes mellitus: effects of insulin treatment . General Pharmacology 24

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Gregory S Y Ong and Morag J Young

et al . 2006 ). Activation of the endothelial MR can both increase and reduce vascular reactivity and tone suggesting a complex regulatory framework, but there is also heterogeneity of experimental conditions in the literature. These differences

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T Zhao, H Zhang, C Jin, F Qiu, Y Wu, and L Shi

of melatonin on vascular reactivity: possible role of vasoactive mediators . Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 130 357 – 367 ( doi:10.1016/s1532-0456(01)00261-7 ). Bukiya AN Liu J Toro L

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Özlem Erdogdu, Linnéa Eriksson, Hua Xu, Åke Sjöholm, Qimin Zhang, and Thomas Nyström

by elevated glucose . American Journal of Physiology 263 H321 – H326 . Tripathy D Mohanty P Dhindsa S Syed T Ghanim H Aljada A Dandona P 2003 Elevation of free fatty acids induces inflammation and impairs vascular reactivity in

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Eugenia Mata-Greenwood, P Naomi Jackson, William J Pearce, and Lubo Zhang

programming of health and disease . Frontiers in Neuroendocrinology 34 27 – 46 . ( doi:10.1016/j.yfrne.2012.11.002 ). Yang S Zhang L 2004 Glucocorticoids and vascular reactivity . Current Vascular Pharmacology 2 1 – 12

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Benjamin Kalbe, Marian Schlimm, Julia Mohrhardt, Paul Scholz, Fabian Jansen, Hanns Hatt, and Sabrina Osterloh

cells. Importantly, it has been shown that the cyclic guanosine monophosphate (cGMP)-dependent protein kinase (PKG) regulates the vascular reactivity and tone in smooth muscle cells through a reduction of the intracellular Ca 2+ levels ( Taylor et al