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Pui-Sin Man, Timothy Wells and David A Carter

important molecular regulator in the adult pituitary is the C2H2 zinc finger transcription factor, early growth response factor 1 (EGR1), that is expressed as a 75 kDa nuclear protein in the rat anterior pituitary ( Tremblay & Drouin 1999 , Wolfe & Call

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Nils Wierup, Frank Sundler and R Scott Heller

al . 1983 ) and gastrin-producing G-cells have been demonstrated in the rat pancreas during neonatal development, while such cells are present, albeit in small numbers, in the pancreas of adult cat and dog ( Larsson et al . 1976 a ). Recently, G

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Hiroshi Nagasaki, Zhiwei Wang, Valerie R Jackson, Steven Lin, Hans-Peter Nothacker and Olivier Civelli

. Analyses of the tissue distribution of the subunits using RT-PCR showed that GPA2 exhibits a wider distribution than GPB5, whose expression is restricted to the pituitary, thyroid, heart, and oviduct in the rat. Immunohistological studies on anterior

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Yiyan Wang, Xiaoheng Li, Fei Ge, Kaiming Yuan, Zhijian Su, Guimin Wang, Qingquan Lian and Ren-Shan Ge

-day-old) rat testis ( Ge et al . 2006 ) and are shown to have the capability of self-renewing or differentiating into androgen-producing Leydig cell lineage. The first cell seen in the Leydig cell lineage is the spindle-shaped progenitor Leydig cell

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Muhammad Ishaq, Anne-Laure Schang, Solange Magre, Jean-Noël Laverrière, Aurélien Guillou, Noëlline Coudouel, Richard Wargnier, Joëlle Cohen-Tannoudji and Raymond Counis

illustrated by the archetypal rat gonads ( Clayton & Catt 1981 , Scott et al . 2009 ). Little is known about the mechanisms and factors governing the expression of Gnrhr in non-pituitary tissues. Most studies have indeed focused on the pituitary gland

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C Bois, C Delalande, M Nurmio, M Parvinen, L Zanatta, J Toppari and S Carreau

progress synchronously through the stages of seminiferous epithelium. In rat, 14 stages (I–XIV) have been described ( Leblond & Clermont 1952 , Parvinen 1982 , Wing & Christensen 1982 ). During their progression, germ cells undergo structural and

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Edson F Nogueira, Claudia A Vargas, Mélissa Otis, Nicole Gallo-Payet, Wendy B Bollag and William E Rainey

pathway, namely p42/p44 mapk (also called extracellular signal-regulated kinase (ERK) 1/2) in bovine ( Chabre et al . 1995 ) and rat ( Cote et al . 1998 , McNeill et al . 1998 ). In addition, AT1 receptors can signal through G protein

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Li Zhang, Jie Gao and Sheng Cui

Introduction The rat ovaries receive their sympathetic innervation from two sources. One is the ovarian plexus nerve, which travels along the ovarian artery, and the other is the superior ovarian nerve (SON), which is associated with the

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Yu-Feng Zhao, Li Wang, Dingjun Zha, Li Qiao, Lianjun Lu, Jun Yu, Ping Qu, Qiang Sun, Jianhua Qiu and Chen Chen

influence insulin secretion in rat and mouse islets in primary culture ( Briscoe et al . 2006 ). The detailed effects of GW9508 on the function of β-cells in primary culture are not well known. In our previous study, we found that GW9508 activates ATP

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Qiaorong Jiang, Kyeong-Hoon Jeong, Cheryl D Horton and Lisa M Halvorson

regulation of the rat LHβ gene promoter. In early experiments, we observed persistent Pitx1-stimulated promoter activity despite mutation of the previously described Pitx1 cis -element at position −101. In the studies reported here, we identify a second