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L B James-Allan Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK

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G S Whitley Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK

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K Leslie Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK
Fetal Medicine Unit, St. George’s Hospital, London, UK

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A E Wallace Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK

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J E Cartwright Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK

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and more than 10 weeks gestation ( Robson et al. 2012 , Wallace et al. 2015 ). Inadequate trophoblast invasion and reduced spiral artery remodelling are associated with pre-eclampsia and foetal growth restriction (FGR) ( Pijnenborg et al. 1991

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-17-0243
Volume/Issue:
Volume 60: Issue 3
Open access
Tristan M Lovell School of Biological Sciences, University of Reading, Reading RG6 6AJ, UK
Department of Obstetrics and Gynaecology, St George’s Hospital, London SW17 0QT, UK
Bruker Daltonics Limited, Coventry CV4 9GH, UK
National Institute for Medical Research, Mill Hill, London NW7 1AA, UK

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Russell J Woods School of Biological Sciences, University of Reading, Reading RG6 6AJ, UK
Department of Obstetrics and Gynaecology, St George’s Hospital, London SW17 0QT, UK
Bruker Daltonics Limited, Coventry CV4 9GH, UK
National Institute for Medical Research, Mill Hill, London NW7 1AA, UK

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David J Butlin School of Biological Sciences, University of Reading, Reading RG6 6AJ, UK
Department of Obstetrics and Gynaecology, St George’s Hospital, London SW17 0QT, UK
Bruker Daltonics Limited, Coventry CV4 9GH, UK
National Institute for Medical Research, Mill Hill, London NW7 1AA, UK

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Kerensa J Brayley School of Biological Sciences, University of Reading, Reading RG6 6AJ, UK
Department of Obstetrics and Gynaecology, St George’s Hospital, London SW17 0QT, UK
Bruker Daltonics Limited, Coventry CV4 9GH, UK
National Institute for Medical Research, Mill Hill, London NW7 1AA, UK

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Isaac T Manyonda School of Biological Sciences, University of Reading, Reading RG6 6AJ, UK
Department of Obstetrics and Gynaecology, St George’s Hospital, London SW17 0QT, UK
Bruker Daltonics Limited, Coventry CV4 9GH, UK
National Institute for Medical Research, Mill Hill, London NW7 1AA, UK

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Jackie Jarvis School of Biological Sciences, University of Reading, Reading RG6 6AJ, UK
Department of Obstetrics and Gynaecology, St George’s Hospital, London SW17 0QT, UK
Bruker Daltonics Limited, Coventry CV4 9GH, UK
National Institute for Medical Research, Mill Hill, London NW7 1AA, UK

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Steve Howell School of Biological Sciences, University of Reading, Reading RG6 6AJ, UK
Department of Obstetrics and Gynaecology, St George’s Hospital, London SW17 0QT, UK
Bruker Daltonics Limited, Coventry CV4 9GH, UK
National Institute for Medical Research, Mill Hill, London NW7 1AA, UK

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Philip J Lowry School of Biological Sciences, University of Reading, Reading RG6 6AJ, UK
Department of Obstetrics and Gynaecology, St George’s Hospital, London SW17 0QT, UK
Bruker Daltonics Limited, Coventry CV4 9GH, UK
National Institute for Medical Research, Mill Hill, London NW7 1AA, UK

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Introduction The placenta is known to control the mother’s metabolism for the benefit of the foetus often, as in pre-eclampsia, to the mother’s detriment. In this, it is comparable to parasites which have also evolved sophisticated

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-07-0007
Volume/Issue:
Volume 39: Issue 3
Free access
Yachao Zhang Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China
Key Laboratory of Animal Resistance Biology of Shandong Province, College of Life Science, Shandong Normal University, Ji’nan, Shandong, China

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Jieqiong Yang Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China

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Shijian Lv Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China

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Dong-Qin Zhao Key Laboratory of Animal Resistance Biology of Shandong Province, College of Life Science, Shandong Normal University, Ji’nan, Shandong, China

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Zi-Jiang Chen Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China

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Wei-Ping Li Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China

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Cong Zhang Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China
Key Laboratory of Animal Resistance Biology of Shandong Province, College of Life Science, Shandong Normal University, Ji’nan, Shandong, China

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.11.6609 Nishizawa H Pryor-Koishi K Kato T Kowa H Kurahashi H Udagawa Y 2007 Microarray analysis of differentially expressed fetal genes in placental tissue derived from early and late onset severe pre-eclampsia . Placenta 28 487 – 497 . ( https://doi.org/10

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-17-0180
Volume/Issue:
Volume 60: Issue 2
Free access
Jie Yang Department of Pathophysiology, Department of Physiology, School of Basic Medical Sciences, Capital Medical University, 10 Xitoutiao, You An Men, Beijing 100069, People's Republic of China

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Jianyu Shang Department of Pathophysiology, Department of Physiology, School of Basic Medical Sciences, Capital Medical University, 10 Xitoutiao, You An Men, Beijing 100069, People's Republic of China

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Suli Zhang Department of Pathophysiology, Department of Physiology, School of Basic Medical Sciences, Capital Medical University, 10 Xitoutiao, You An Men, Beijing 100069, People's Republic of China

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Hao Li Department of Pathophysiology, Department of Physiology, School of Basic Medical Sciences, Capital Medical University, 10 Xitoutiao, You An Men, Beijing 100069, People's Republic of China

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Huirong Liu Department of Pathophysiology, Department of Physiology, School of Basic Medical Sciences, Capital Medical University, 10 Xitoutiao, You An Men, Beijing 100069, People's Republic of China
Department of Pathophysiology, Department of Physiology, School of Basic Medical Sciences, Capital Medical University, 10 Xitoutiao, You An Men, Beijing 100069, People's Republic of China

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KH 2009 Angiotensin II type 1 and 2 receptors polymorphisms in pre-eclampsia and normal pregnancy in three different populations . Acta Obstetricia et Gynecologica Scandinavica 88 606 – 611 . ( doi:10.1080/00016340902859307 ). Anton L

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-12-0216
Volume/Issue:
Volume 50: Issue 2
Free access
Nadia Bellofiore The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Australia
Obstetrics and Gynaecology, Monash University, Clayton, Australia

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Fiona Cousins The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Australia
Obstetrics and Gynaecology, Monash University, Clayton, Australia

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Peter Temple-Smith Obstetrics and Gynaecology, Monash University, Clayton, Australia

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Hayley Dickinson The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Australia
Obstetrics and Gynaecology, Monash University, Clayton, Australia

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Jemma Evans Centre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Australia

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show vascular remodelling and hence is not able to model diseases such as pre-eclampsia, placenta accreta or recurrent miscarriage due to inadequate angiogenesis of the spiral arterioles. This emphasises the important research and clinical translation

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-17-0278
Volume/Issue:
Volume 61: Issue 1
Free access
Haiqin Wang Department of Obstetrics and Gynecology, the Fifth People’s Hospital of Jinan, Jinan, Shandong, China

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Li Nian Department of Intensive Care Unit, the Fourth People’s Hospital of Jinan, Jinan, Shandong, China

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Zhonghua Li Department of Burn and Plastic Surgery, the Fourth People’s Hospital of Jinan, Jinan, Shandong, China

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Changhui Lu Department of Nursing, the Fourth People’s Hospital of Jinan, Jinan, Shandong, China

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-cell subsets . Immunological Reviews 252 41 – 51 . ( https://doi.org/10.1111/imr.12033 ) Redman CW Sargent IL 2010 Immunology of pre-eclampsia . American Journal of Reproductive Immunology 63 534 – 543 . ( https://doi.org/10.1111/j.1600

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-20-0308
Volume/Issue:
Volume 66: Issue 3
Restricted access
Philip Lowry School of Biological Sciences, University of Reading, Reading, UK

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Russell Woods School of Biological Sciences, University of Reading, Reading, UK

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Danisman N 2010 Association of maternal serum high sensitive C-reactive protein level with body mass index and severity of pre-eclampsia at third trimester . Journal of Obstetrics and Gynaecology Research 36 970 – 977 . ( https://doi.org/10

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-17-0275
Volume/Issue:
Volume 60: Issue 1
Free access
Karen Oliva UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia
UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia
UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia

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Gillian Barker UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia
UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia
UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia

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Clyde Riley UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia
UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia

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Mark J Bailey UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia

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Michael Permezel UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia
UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia

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Gregory E Rice UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia

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Martha Lappas UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia
UQ Centre for Clinical Research, Department of Obstetrics and Gynaecology, Mercy Perinatal Research Centre, The University of Queensland, Brisbane, Queensland, Australia

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. 2010 ). Obesity in pregnancy is associated with substantially increased risks for both mother and infant ( Heslehurst et al . 2008 ). Gestational diabetes, pre-eclampsia, Caesarean section, instrumental vaginal delivery, birth trauma and pelvic floor

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-11-0123
Volume/Issue:
Volume 48: Issue 2
Free access
Yingchun Li Department of Obstetrics and Gynecology, Division of Reproductive Sciences, University of Colorado School of Medicine, Aurora, Colorado, USA

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Ramón A Lorca Department of Obstetrics and Gynecology, Division of Reproductive Sciences, University of Colorado School of Medicine, Aurora, Colorado, USA

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Emily J Su Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine/Division of Reproductive Sciences, University of Colorado School of Medicine, Aurora, Colorado, USA

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10.1053/j.semperi.2007.11.004 Bartsch E Medcalf KE Park AL Ray JG & High Risk of Pre-eclampsia Identification G 2016 Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-17-0139
Volume/Issue:
Volume 60: Issue 1
Free access
Jonathan Pham Department of Pathology, University of California San Diego, La Jolla, California, USA
Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA

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Kanaga Arul Nambi Rajan Department of Pathology, University of California San Diego, La Jolla, California, USA
Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA

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Ping Li Department of Pathology, Medical School of Jinan University, Guangzhou, China

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Mana M Parast Department of Pathology, University of California San Diego, La Jolla, California, USA
Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA

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direct targets of placental Sirt1. Sirt1-PPAR γ signaling in placental disease Alterations in trophoblast differentiation and placental development are associated with numerous pregnancy complications, including miscarriage, pre-eclampsia

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-17-0315
Volume/Issue:
Volume 60: Issue 4
Free access