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Zhiyu Ma College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China
College of Veterinary Medicine, Yangzhou University, Yangzhou, People’s Republic of China

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Ying Zhang College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Juan Su College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Sheng Yang College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Wenna Qiao College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Xiang Li College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Zhihai Lei College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Ling Cheng College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Na An College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Wenshao Wang College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Yanyan Feng College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People’s Republic of China

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Jinlong Zhang College of Veterinary Medicine, Yangzhou University, Yangzhou, People’s Republic of China

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stimulate the proliferation of porcine Leydig cells. Pigs play not only an important role in animal husbandry but are also one of the most commonly used animals experimental studies, especially as an application-appropriate model for studies related to

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G Schuler Veterinary Clinic for Obstetrics, Gynecology and Andrology, Faculty of Veterinary Medicine, Justus-Liebig-University, Giessen, Germany

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Y Dezhkam Veterinary Clinic for Obstetrics, Gynecology and Andrology, Faculty of Veterinary Medicine, Justus-Liebig-University, Giessen, Germany

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L Tenbusch Veterinary Clinic for Obstetrics, Gynecology and Andrology, Faculty of Veterinary Medicine, Justus-Liebig-University, Giessen, Germany

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MC Klymiuk Veterinary Clinic for Obstetrics, Gynecology and Andrology, Faculty of Veterinary Medicine, Justus-Liebig-University, Giessen, Germany

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B Zimmer Veterinary Clinic for Obstetrics, Gynecology and Andrology, Faculty of Veterinary Medicine, Justus-Liebig-University, Giessen, Germany

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B Hoffmann Veterinary Clinic for Obstetrics, Gynecology and Andrology, Faculty of Veterinary Medicine, Justus-Liebig-University, Giessen, Germany

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porcine Leydig cells ( Hobkirk et al . 1989 ) provided clear evidence that in boars testicular estrogens are sulfonated in Leydig cells immediately after their production from aromatizable precursors. However, the concept of the Leydig cell as the only

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P A Sinclair Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada N1G 2W1

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W J Gilmore Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada N1G 2W1

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Z Lin Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada N1G 2W1

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Y Lou Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada N1G 2W1

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E J Squires Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada N1G 2W1

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activity in porcine Leydig cells. Primary porcine Leydig cells were isolated from mature Yorkshire boars and the SULT2A1 activity was determined. Leydig cells were cultured in the presence of CITCO (1 μM), TCPOBOP (250 nM), phenobarbital (2 mM), phenytoin

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B Zimmer Veterinary Clinic for Obstetrics, Gynecology and Andrology, Justus-Liebig-University, Giessen, Germany

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L Tenbusch Veterinary Clinic for Obstetrics, Gynecology and Andrology, Justus-Liebig-University, Giessen, Germany

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M C Klymiuk Veterinary Clinic for Obstetrics, Gynecology and Andrology, Justus-Liebig-University, Giessen, Germany

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Y Dezhkam Veterinary Clinic for Obstetrics, Gynecology and Andrology, Justus-Liebig-University, Giessen, Germany

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G Schuler Veterinary Clinic for Obstetrics, Gynecology and Andrology, Justus-Liebig-University, Giessen, Germany

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in porcine testicular cytosol ( Cooke et al . 1983 , Sinclair et al . 2006 ) or preparations obtained after chromatography of cytosol prepared from purified porcine Leydig cells ( Hobkirk et al . 1989 ). However, 3 H-activities associated with

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Gabriela Silva Monteiro de Paula Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Marianna Wilieman Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Karina Ribeiro Silva Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Post-Graduation Program of Biotechnology, National Institute of Metrology, Quality and Technology – INMETRO, Rio de Janeiro, Brazil
Multidisciplinary Center for Biological Research (Numpex-Bio), Federal University of Rio de Janeiro – Campus of Duque de Caxias, Rio de Janeiro, Brazil

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Leandra Santos Baptista Post-Graduation Program of Biotechnology, National Institute of Metrology, Quality and Technology – INMETRO, Rio de Janeiro, Brazil
Multidisciplinary Center for Biological Research (Numpex-Bio), Federal University of Rio de Janeiro – Campus of Duque de Caxias, Rio de Janeiro, Brazil

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Sihem Boudina Department of Nutrition and Integrative Physiology, University of Utah School of Medicine, Salt Lake City, Utah, USA

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Luana Lopes de Souza Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Thais Bento-Bernardes Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Karina Dutra Asensi Cellular and Molecular Cardiology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
National Center of Structural Biology and Bioimage – CENABIO, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Regina Coeli dos Santos Goldenberg Cellular and Molecular Cardiology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Carmen Cabanelas Pazos-Moura Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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neuromedin B on steroidogenesis, cell proliferation and apoptosis in porcine Leydig cells . Journal of Molecular Endocrinology 61 . ( https://doi.org/10.1530/JME-17-0242 ) 29632025 McDonald TJ Jörnvall H Nilsson G Vagne M Ghatei M Bloom SR

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Pulak R Manna Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA

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Syam P Chandrala Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA

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Youngah Jo Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA

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Douglas M Stocco Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA

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. Mauduit C , Chauvin MA, Hartmann DJ, Revol A, Morera AM & Benahmed M 1992 Interleukin-1 alpha as a potent inhibitor of gonadotropin action in porcine Leydig cells: site(s) of action. Biology of Reproduction 46 1119 –1126

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