Search Results

You are looking at 1 - 10 of 16 items for :

  • "microbiota" x
Clear All
Restricted access

Mohamed H Noureldein, Sara Bitar, Natalie Youssef, Sami Azar and Assaad A Eid

healthy microbiota ( Mejía-León & Barca 2015 , Haro et al. 2016 ), a condition known as diabetic dysbiosis. Evidence from literature suggests that gut microbiota plays a central role in the pathogenesis of T2DM ( Manco et al. 2010 , Musso et al

Free access

Pierre Poinsot, Martin Schwarzer, Noël Peretti and François Leulier

& Klibanski 2014 ). For several years, the functional links between the nutritional status and the gut microbiota have been established. In humans, undernutrition has been associated with major gut microbiota alterations, which correlate with poor growth

Free access

Shaoqian Zhao, Wen Liu, Jiqiu Wang, Juan Shi, Yingkai Sun, Weiqing Wang, Guang Ning, Ruixin Liu and Jie Hong

development of metabolic diseases is affected by genetics and environmental factors ( Ussar et al . 2015 ). Gut microbiota, acting as an environmental factor, is linked to the development and progression of obesity and T2DM ( Cani et al . 2012 ). A

Free access

Ana Luísa Neves, João Coelho, Luciana Couto, Adelino Leite-Moreira and Roberto Roncon-Albuquerque Jr

epithelium is an efficient barrier that prevents absorption of LPS derived from Gram-negative gut microbiota. Obesity, high-fat diet, diabetes, and NAFLD are associated with higher gut permeability leading to metabolic endotoxemia. Probiotics, prebiotics, and

Free access

Sufang Chen, Wei Wei, Minjie Chen, Xiaobo Qin, Lianglin Qiu, Li Zhang, Yuhao Zhang, Qi Cao and Zhekang Ying

homeostatic regulation of glucose metabolism by the gut microbiota ( Everard & Cani 2014 , Zhao et al . 2018 ). Given the well-established role of TNF signaling in inflammation ( Vinay & Kwon 2012 ) and the latter in the regulation of glucose homeostasis by

Free access

Jinghua Peng and Ling He

. Endotoxemia-mediated P300 induction through the activation of the IRE1-XBP1s pathway A high-fat, western-style diet is an important predisposing factor for the onset of diabetes and obesity. HFD feeding results in changes in gut microbiota that initiate

Free access

Guojun Shi, Chen Sun, Weiqiong Gu, Minglan Yang, Xiaofang Zhang, Nan Zhai, Yan Lu, Zhijian Zhang, Peishun Shou, Zhiguo Zhang and Guang Ning

Gut microbiota-derived propionate reduces cancer cell proliferation in the liver . British Journal of Cancer 107 1337 – 1344 . ( doi:10.1038/bjc.2012.409 ). Bindels LB Dewulf EM Delzenne NM 2013 GPR43/FFA2: physiopathological relevance

Free access

Emily Tubbs and Jennifer Rieusset

importance of the gut–liver axis in the adaptation to nutritional environment changes ( Chassaing et al . 2014 ). However, excess of nutrients or intestinal microbiota modifications (i.e. altered microbiota population and/or altered gut permeability) could

Free access

Yu-Guang Ma, Liang Liang, Yin-Bin Zhang, Bao-Feng Wang, Yun-Gang Bai, Zhi-Jun Dai, Man-Jiang Xie and Zhong-Wei Wang

). The berberine treatment reduced blood pressure and improved dilation in diabetic rats by direct activation of BK Ca channel in VSMCs After oral administration, berberine can be absorbed through the gastrointestinal tract, where the gut microbiota

Free access

Qin He, Dan Mei, Sha Sha, Shanshan Fan, Lin Wang and Ming Dong

Pang X Xu J Kang C Li M Zhang C Zhang Z Zhang Y 2012 Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats . PLoS ONE 7 e42529 . ( doi:10