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L B James-Allan Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK

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G S Whitley Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK

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K Leslie Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK
Fetal Medicine Unit, St. George’s Hospital, London, UK

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A E Wallace Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK

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J E Cartwright Molecular and Clinical Sciences Research Institute, St. George’s, University of London, London, UK

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. 1999 , Ashton et al. 2005 ). Chemotaxis assay SGHPL-4 cell chemotaxis toward rDSC CM was measured using the μ-Slide Chemotaxis 2D assay (Ibidi, Martinsried, Germany), according to the manufacturer’s instructions and a previously described

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-17-0243
Volume/Issue:
Volume 60: Issue 3
Open access
Xiao-Qiu Wang Laboratory for Reproductive Immunology, Department of Obstetrics and Gynecology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, Shanghai 200011, People's Republic of China

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Jing Yu Laboratory for Reproductive Immunology, Department of Obstetrics and Gynecology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, Shanghai 200011, People's Republic of China

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Xue-Zhen Luo Laboratory for Reproductive Immunology, Department of Obstetrics and Gynecology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, Shanghai 200011, People's Republic of China

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Ying-Li Shi Laboratory for Reproductive Immunology, Department of Obstetrics and Gynecology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, Shanghai 200011, People's Republic of China

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Yun Wang Laboratory for Reproductive Immunology, Department of Obstetrics and Gynecology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, Shanghai 200011, People's Republic of China

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Ling Wang Laboratory for Reproductive Immunology, Department of Obstetrics and Gynecology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, Shanghai 200011, People's Republic of China

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Da-Jin Li Laboratory for Reproductive Immunology, Department of Obstetrics and Gynecology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, Shanghai 200011, People's Republic of China
Laboratory for Reproductive Immunology, Department of Obstetrics and Gynecology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, Shanghai 200011, People's Republic of China

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, and U937 cells (2×10 5 cells/well) were put into the upper chamber after incubation for 48 h. Anti-RANTES-neutralizing antibody (R&D Systems) at 2.5 μg/ml was added to several lower chambers half an hour before chemotaxis assay. After 3 h of

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-09-0177
Volume/Issue:
Volume 45: Issue 5
Free access
Huixia Li Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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Zhuanmin Zhang Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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Dongxu Feng Hong Hui Hospital, Xi’an Jiaotong University School of Medicine, Xi’an, Shaanxi, China
Center for Translational Medicine, The First Affiliated Hospital of Medical School of Xi’an Jiaotong University, Xi’an, Shaanxi, China

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Lin Xu Department of Endocrinology, The Affiliated Guangren Hospital, Medical School of Xi’an Jiaotong University, Xi’an, Shaanxi, China

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Fang Li Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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Jiali Liu Department of Clinical Laboratory, Xi’an Jiaotong University Second Affiliated Hospital, Xi’an, Shaanxi, China

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Xinxin Jin Hong Hui Hospital, Xi’an Jiaotong University School of Medicine, Xi’an, Shaanxi, China

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Zhuang Qian Hong Hui Hospital, Xi’an Jiaotong University School of Medicine, Xi’an, Shaanxi, China

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Xiaomin Kang Hong Hui Hospital, Xi’an Jiaotong University School of Medicine, Xi’an, Shaanxi, China

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Hongzhi Sun Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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et al . 2013 ). Accordingly, we also found PGRN could function as a chemotactic protein for Raw 264.7 cells. The extent of in vitro PGRN-mediated chemotaxis is similar to that of MCP-1. Moreover, multivariable linear regression analyses revealed CRP

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-19-0211
Volume/Issue:
Volume 64: Issue 3
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Mirel-Adrian Popa Institute of Cellular Biology and Pathology ‘Nicolae Simionescu’ of the Romanian Academy, Bucharest, Romania

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Maria-Cristina Mihai Institute of Cellular Biology and Pathology ‘Nicolae Simionescu’ of the Romanian Academy, Bucharest, Romania

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Alina Constantin Institute of Cellular Biology and Pathology ‘Nicolae Simionescu’ of the Romanian Academy, Bucharest, Romania

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Viorel Şuică Institute of Cellular Biology and Pathology ‘Nicolae Simionescu’ of the Romanian Academy, Bucharest, Romania

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Cătălin Ţucureanu Infection and Immunity Laboratory, National Institute for Research and Development in Microbiology and Immunology ‘I. Cantacuzino’, Bucharest, Romania

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Raluca Costache Department of Obstetrics and Gynecology, Clinical Hospital ‘Dr. Ioan Cantacuzino’, Bucharest, Romania

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Felicia Antohe Institute of Cellular Biology and Pathology ‘Nicolae Simionescu’ of the Romanian Academy, Bucharest, Romania

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Raghvendra K Dubey Department for Reproductive Endocrinology, University Hospital Zurich, Schlieren, Switzerland
Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland

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Maya Simionescu Institute of Cellular Biology and Pathology ‘Nicolae Simionescu’ of the Romanian Academy, Bucharest, Romania

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process such as proteolysis of fibrotic/scar tissue to promote MSC adhesion, angiogenesis/growth (proliferation, migration) and tissue repair. We report here that stimulation of MSC with DHT induces increased cell proliferation, migration and chemotaxis

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-17-0185
Volume/Issue:
Volume 60: Issue 1
Free access
Yihong Wan Department of Pharmacology, Gene Expression Laboratory, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Room ND8.502B, Dallas, Texas 75390-9041, USA
Department of Pharmacology, Gene Expression Laboratory, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Room ND8.502B, Dallas, Texas 75390-9041, USA

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Ronald M Evans Department of Pharmacology, Gene Expression Laboratory, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Room ND8.502B, Dallas, Texas 75390-9041, USA

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likely due to impaired monocyte chemotaxis ( Combadiere et al . 2007 ). Furthermore, the T280M mutation was independently associated with a lower risk of cardiovascular disease, possibly as the result of reduced cell–cell adhesion under physiological

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-09-0090
Volume/Issue:
Volume 44: Issue 2
Open access
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S Sivagurunathan
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C N Pagel
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L H Loh
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L C Wijeyewickrema Faculty of Veterinary Science, Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia

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R N Pike Faculty of Veterinary Science, Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia

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E J Mackie
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-independent responses of cells to thrombin have also previously been described. For example, proteolytically inactive thrombin induces chemotaxis of neutrophils and PBMCs and a non-proteolytic thrombin peptide induces cytokine release from PBMCs ( Bar-Shavit et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-12-0177
Volume/Issue:
Volume 50: Issue 3
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Feng Fang Breast Cancer Program, Division of Rheumatology, Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center and Departments of Pathology

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Jiamao Zheng Breast Cancer Program, Division of Rheumatology, Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center and Departments of Pathology

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Traci L Galbaugh Breast Cancer Program, Division of Rheumatology, Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center and Departments of Pathology

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Alyson A Fiorillo Breast Cancer Program, Division of Rheumatology, Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center and Departments of Pathology

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Elizabeth E Hjort Breast Cancer Program, Division of Rheumatology, Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center and Departments of Pathology

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Xianke Zeng Breast Cancer Program, Division of Rheumatology, Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center and Departments of Pathology

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Charles V Clevenger Breast Cancer Program, Division of Rheumatology, Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center and Departments of Pathology

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breast carcinoma cell line MDA-MB231 promoted chemotaxis of bone marrow-derived mesenchymal stromal cells ( Lin et al . 2008 ). However, despite these insights into CypB action, the function of CypB during PRL-induced gene expression and action in breast

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https://doi.org/10.1677/JME-09-0140
Volume/Issue:
Volume 44: Issue 6
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Guojun Shi Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China
Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Chen Sun Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China
Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Weiqiong Gu Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Minglan Yang Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Xiaofang Zhang Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Nan Zhai Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Yan Lu Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Zhijian Zhang Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Peishun Shou Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Zhiguo Zhang Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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Guang Ning Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China
Shanghai Institute of Endocrinology and Metabolism, Laboratory of Endocrinology and Metabolism, Key Laboratory of Stem Cell Biology, Endocrine and Metabolic E-Institutes of Shanghai Universities (EISU), Shanghai Clinical Center for Endocrine and Metabolic Diseases and Key Laboratory for Endocrinology and Metabolism of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197th Ruijin 2nd Road, Shanghai 200025, China

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between the natural ligands and synthetic ligands provides the possibility for us to develop our study further to clarify the model. The role of PA1 itself in the chemotaxis response of neutrophils ( Vinolo et al . 2011 ) and Gα i/o -mediated

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-14-0065
Volume/Issue:
Volume 53: Issue 3
Free access
Ralf Stumm Institute of Pharmacology and Toxicology, Otto-von-Guericke-University Magdeburg, Leipziger Strasse 44, 39120 Magdeburg, Germany

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Volker Höllt Institute of Pharmacology and Toxicology, Otto-von-Guericke-University Magdeburg, Leipziger Strasse 44, 39120 Magdeburg, Germany

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Experimental Neurology 63 84 –96. Klein RS , Rubin JB, Gibson HD, DeHaan EN, Alvarez-Hernandez X, Segal RA & Luster AD 2001 SDF-1 alpha induces chemotaxis and enhances Sonic hedgehog-induced proliferation of cerebellar granule

Article Type:
Review Article
DOI:
https://doi.org/10.1677/JME-06-0032
Volume/Issue:
Volume 38: Issue 3
Free access
H Roger Lijnen Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, KU Leuven, Campus Gasthuisberg, Onderwijs & Navorsing 1, Herestraat 49, Box 911, B-3000 Leuven, Belgium

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Ilse Scroyen Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, KU Leuven, Campus Gasthuisberg, Onderwijs & Navorsing 1, Herestraat 49, Box 911, B-3000 Leuven, Belgium

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1982 Differentiation-dependent stimulation of neovascularization and endothelial cell chemotaxis by 3T3 adipocytes . PNAS 79 5597 – 5601 . ( doi:10.1073/pnas.79.18.5597 ). Donato MT Gomez-Lechon MJ 2012 Drug-induced liver steatosis and

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Research Article
DOI:
https://doi.org/10.1530/JME-12-0244
Volume/Issue:
Volume 50: Issue 3
Free access