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Rafaela Fadoni Alponti, Luciana Godoy Viana, Norma Yamanouye and Paulo Flavio Silveira

et al . 2010 , Dimitriadis et al . 2011 ). This vesicle contains glucose transporter type 4 (GLUT4) and insulin-regulated aminopeptidase (IRAP, EC 3.4.11.3) ( Keller et al . 1995 , Keller 2004 , Jordens et al . 2010 ). Hydrolytic activity on

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Anthony L Albiston, Mauricio Cacador, Puspha Sinnayah, Peta Burns and Siew Yeen Chai

Introduction Insulin-regulated aminopeptidase (IRAP) is a marker protein for specialized vesicles containing the insulin-responsive glucose transporter 4 (GLUT4) ( Keller et al . 1995 ). IRAP is localized in distinct organelles within insulin

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D G Smyth

leucine aminopeptidase, an enzyme that removes amino acids from the NH 2 terminus. We also digested the two peptides with a membrane-bound aminopeptidase from rat brain. In both cases, under conditions where the enkephalin was rapidly degraded, β

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Kamran Ullah, Tanzil Ur Rahman, Hai-Tao Pan, Meng-Xi Guo, Xin-Yan Dong, Juan Liu, Lu-Yang Jin, Yi Cheng, Zhang-Hong Ke, Jun Ren, Xian-Hua Lin, Xiao-Xiao Qiu, Ting-Ting Wang, He-Feng Huang and Jian-Zhong Sheng

/MRP protein subunit POP1 2.8711 10.4 20.7 2 POP1 3.27E-02 −1.34 Q9Y6K0 Choline/ethanolaminephosphotransferase 1 3.1822 4.8 46.553 2 CEPT1 3.59E-02 1.3 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 12.72 5.2 107

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Yoo Mee Kim, Juan Ji An, Yong-Jun Jin, Yumie Rhee, Bong Soo Cha, Hyun Chul Lee and Sung-Kil Lim

neovascularization via endothelial cell cycle arrest in the late G1 phase ( Abe et al. 1994 ). Methionine aminopeptidase-2 (MetAP2) has been identified as a molecular target. However, the link between MetAP2 inhibition and endothelial cell cycle arrest by

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Niamh X Cawley, Zhaojin Li and Y Peng Loh

-POMC, ACTH, and β-LPH. A more comprehensive processing pattern is seen in the IL and hypothalamus, yielding α-MSH and β-endorphin. APB, aminopeptidase B-like; AACE, acidic ACTH-converting enzyme; CPE, carboxypeptidase E; NAT, N -acetyltransferase; PAM

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Ahmed A Hasan and Berthold Hocher

B Lazarevic G Vlahovic P Rajic M Stefanovic V 2008 Diagnostic value of the aminopeptidase N,N-acetyl-beta-D-glucosaminidase and dipeptidylpeptidase IV in evaluating tubular dysfunction in patients with glomerulopathies . Renal

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Xun Cao, Xiao Zhou, Xiao-Min Liu and Li-Hong Zhou

-surface aminopeptidase with serine protease activity, belonging to the S9B family of serine proteases ( Röhrborn et al. 2015 ). It is expressed on the apical surfaces of epithelial and acinar cells and in endothelial cells, fibroblasts, and lymphocytes ( Dinjens et al

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Lena Espelage, Hadi Al-Hasani and Alexandra Chadt

-mediated impairments in glucose transport are mainly based on the reduction in GLUT4 abundance and only secondary on defects in transporter trafficking. Both RabGAPs interact physically with the GLUT4 vesicle-resident protein insulin-regulated aminopeptidase (IRAP

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Seung-Chul Kim, Jae-Eon Lee, Seong Soo Kang, Hoe-Saeng Yang, Sun Suk Kim and Beum-Soo An

-time PCR (Q-PCR) was performed with cDNA template (2 μL) and 2 × Power SYBR Green (6 μL; TOYOBO Co., Osaka, Japan)-containing specific primers. Primer sequences for β-actin (control gene), OXT, OXTR and placental leucine aminopeptidase (P-LAP) are shown in