cardiomyopathy, which will lead to explore novel therapeutic approaches for alleviating cardiac injuries and preventing detrimental outcomes. Adipose tissue, mainly comprising neutral lipid, is closely correlated with amounts of clinical parameters such as
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Yousheng Xu, Yongshun Wang, Jingjin Liu, Wei Cao, Lili Li, Hongwei Du, Enbo Zhan, Ruoxi Zhang, Huimin Liu, Maoen Xu, Tao Chen, Yilin Qu, and Bo Yu
Maria J Salazar, Adriana R Rodrigues, Mafalda Sousa, José Magalhães, Delminda Neves, Henrique Almeida, and Alexandra M Gouveia
. Consequence of insulin resistance and ectopic deposition of lipids, several diseases stem from obesity, such as stroke and other cardiovascular conditions, type 2 diabetes, osteoarthritis and some types of cancer ( Goossens 2017 ). White adipose tissue (WAT
Janne Lebeck
Glycerol metabolism The metabolic switching between feeding and fasting is central to everyday life and involves tight hormonal control with effects on muscle, adipose tissue, and liver that maintains an adequate handling of metabolic precursors to
Jacqueline M Wallace, John S Milne, Raymond P Aitken, Dale A Redmer, Lawrence P Reynolds, Justin S Luther, Graham W Horgan, and Clare L Adam
content, which result in decreased financial returns for the producer ( Greenwood et al . 2010 , Nissen & Oksbjerg 2010 ). In precocial mammals, appropriate prenatal adipose tissue development is essential for adequate thermoregulation at birth to ensure
Susan M van den Berg, Andrea D van Dam, Pascal J H Kusters, Linda Beckers, Myrthe den Toom, Saskia van der Velden, Jan Van den Bossche, Irma van Die, Mariëtte R Boon, Patrick C N Rensen, Esther Lutgens, and Menno P J de Winther
Introduction Brown adipose tissue (BAT) contributes to the control of body temperature by the production of heat in response to cold. Brown adipocytes have numerous mitochondria that contain uncoupling protein 1 (UCP1). Activation of brown
Jacqueline M Wallace, John S Milne, Raymond P Aitken, and Clare L Adam
gender on offspring outcomes ( Aiken & Ozanne 2013 ). Alterations in the genes regulating adipose tissue proliferation, differentiation, metabolism and signalling are likely to be integral to the development of an obese phenotype, while circulating lipid
Thomas Svava Nielsen, Niels Jessen, Jens Otto L Jørgensen, Niels Møller, and Sten Lund
Introduction The major energy reserve in mammals consists of fat stored in adipose tissue (AT). In periods of excess energy intake, dietary lipids are taken up by fat cells (adipocytes) in AT and esterified into triglycerides (TGs), which are stored
Karen Fjeldborg, Holger J Møller, Bjørn Richelsen, and Steen B Pedersen
Introduction In obesity, there is an increased amount of macrophages in the adipose tissue (AT), which is associated with low-grade inflammation and insulin resistance ( Weisberg et al . 2003 , Dandona et al . 2004 ). CD163 is a membrane
Lingyun Zhang, Takashi Sugiyama, Nao Murabayashi, Takashi Umekawa, Ning Ma, Yuki Kamimoto, Yoshihiro Ogawa, and Norimasa Sagawa
Introduction A chronic low-grade inflammatory state of adipose tissue has been implicated in the development of insulin resistance in non-pregnant (NP) obese subjects ( Weisberg et al . 2003 , Xu et al . 2003 ). Adipocytes in obesity increase
Yuanyuan Huang, Hanlin Zhang, Meng Dong, Lei Zhang, Jun Lin, Rongcai Ye, Huiqiao Zhou, Xiaomeng Liu, and Wanzhu Jin
et al. 2020 ). Measurement of the mitochondrial DNA copy number Total DNA was isolated from BAT and SUB adipose tissue from the WT and TG mice at 21 weeks of age according to the manufacturer’s instructions (Tiangen). The COX II gene was used