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Yousheng Xu, Yongshun Wang, Jingjin Liu, Wei Cao, Lili Li, Hongwei Du, Enbo Zhan, Ruoxi Zhang, Huimin Liu, Maoen Xu, Tao Chen, Yilin Qu and Bo Yu

cardiomyopathy, which will lead to explore novel therapeutic approaches for alleviating cardiac injuries and preventing detrimental outcomes. Adipose tissue, mainly comprising neutral lipid, is closely correlated with amounts of clinical parameters such as

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Janne Lebeck

Glycerol metabolism The metabolic switching between feeding and fasting is central to everyday life and involves tight hormonal control with effects on muscle, adipose tissue, and liver that maintains an adequate handling of metabolic precursors to

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Jacqueline M Wallace, John S Milne, Raymond P Aitken, Dale A Redmer, Lawrence P Reynolds, Justin S Luther, Graham W Horgan and Clare L Adam

content, which result in decreased financial returns for the producer ( Greenwood et al . 2010 , Nissen & Oksbjerg 2010 ). In precocial mammals, appropriate prenatal adipose tissue development is essential for adequate thermoregulation at birth to ensure

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Susan M van den Berg, Andrea D van Dam, Pascal J H Kusters, Linda Beckers, Myrthe den Toom, Saskia van der Velden, Jan Van den Bossche, Irma van Die, Mariëtte R Boon, Patrick C N Rensen, Esther Lutgens and Menno P J de Winther

Introduction Brown adipose tissue (BAT) contributes to the control of body temperature by the production of heat in response to cold. Brown adipocytes have numerous mitochondria that contain uncoupling protein 1 (UCP1). Activation of brown

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Jacqueline M Wallace, John S Milne, Raymond P Aitken and Clare L Adam

gender on offspring outcomes ( Aiken & Ozanne 2013 ). Alterations in the genes regulating adipose tissue proliferation, differentiation, metabolism and signalling are likely to be integral to the development of an obese phenotype, while circulating lipid

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Thomas Svava Nielsen, Niels Jessen, Jens Otto L Jørgensen, Niels Møller and Sten Lund

Introduction The major energy reserve in mammals consists of fat stored in adipose tissue (AT). In periods of excess energy intake, dietary lipids are taken up by fat cells (adipocytes) in AT and esterified into triglycerides (TGs), which are stored

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Karen Fjeldborg, Holger J Møller, Bjørn Richelsen and Steen B Pedersen

Introduction In obesity, there is an increased amount of macrophages in the adipose tissue (AT), which is associated with low-grade inflammation and insulin resistance ( Weisberg et al . 2003 , Dandona et al . 2004 ). CD163 is a membrane

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Lingyun Zhang, Takashi Sugiyama, Nao Murabayashi, Takashi Umekawa, Ning Ma, Yuki Kamimoto, Yoshihiro Ogawa and Norimasa Sagawa

Introduction A chronic low-grade inflammatory state of adipose tissue has been implicated in the development of insulin resistance in non-pregnant (NP) obese subjects ( Weisberg et al . 2003 , Xu et al . 2003 ). Adipocytes in obesity increase

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Stefania Carobbio, Barry Rosen and Antonio Vidal-Puig

Introduction The brown adipose tissue (BAT) is the main site of non-shivering thermogenesis in mammals and it responds to environmental stimuli such as cold and increased lipid-rich hypercaloric caloric intake, a process referred to as adaptive

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N Hoggard, M Cruickshank, K M Moar, P Barrett, S Bashir and J D B Miller

and developmental processes. Recently, INHBB was identified in human white adipose tissue, while INBBA, INBBC and INBBE were expressed at very low levels suggesting that INHBB is the predominant activin in human adipose tissue ( Sjoholm et al . 2006