Filter

Refine by collections

Refine by access

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 1 - 10 of 1,624 items for :

  • "signaling" x
  • Refine by access: All content x
Clear All
Michela Zamboni Institute of Biochemistry and Cell Biology, National Council of Research, Monterotondo, Rome, Italy

Search for other papers by Michela Zamboni in
Google Scholar
PubMed Close
,
Georgios Strimpakos Institute of Biochemistry and Cell Biology, National Council of Research, Monterotondo, Rome, Italy

Search for other papers by Georgios Strimpakos in
Google Scholar
PubMed Close
,
Eleonora Poggiogalle Department of Experimental Medicine – Medical Pathophysiology, Food Science and Endocrinology Section, Sapienza University of Rome, Rome, Italy

Search for other papers by Eleonora Poggiogalle in
Google Scholar
PubMed Close
,
Lorenzo M Donini Department of Experimental Medicine – Medical Pathophysiology, Food Science and Endocrinology Section, Sapienza University of Rome, Rome, Italy

Search for other papers by Lorenzo M Donini in
Google Scholar
PubMed Close
, and
Donato Civitareale Institute of Biochemistry and Cell Biology, National Council of Research, Monterotondo, Rome, Italy

Search for other papers by Donato Civitareale in
Google Scholar
PubMed Close

mechanisms behind this correlation are not fully understood. Since TTF-2 plays a critical role as mediator between extracellular inputs in the maintenance of thyroid-specific gene expression, we hypothesized that it could play a role in adipocyte signaling on

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-22-0129
Volume/Issue:
Volume 70: Issue 1
Free access
Marina C Muñoz Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Marina C Muñoz in
Google Scholar
PubMed Close
,
Verónica G Piazza Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Verónica G Piazza in
Google Scholar
PubMed Close
,
Valeria Burghi Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Valeria Burghi in
Google Scholar
PubMed Close
,
Jorge F Giani Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Jorge F Giani in
Google Scholar
PubMed Close
,
Carolina S Martinez Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Carolina S Martinez in
Google Scholar
PubMed Close
,
Nadia S Cicconi Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Nadia S Cicconi in
Google Scholar
PubMed Close
,
Nadia V Muia Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Nadia V Muia in
Google Scholar
PubMed Close
,
Yimin Fang Department of Internal Medicine, Geriatrics Research, Southern Illinois University School of Medicine, Springfield, Illinois, USA

Search for other papers by Yimin Fang in
Google Scholar
PubMed Close
,
Sergio Lavandero Advanced Center of Chronic Diseases (ACCDiS), Facultad de Ciencias Químicas y Farmacéuticas y Facultad de Medicina, Universidad de Chile, Santiago, Chile
Cardiology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA

Search for other papers by Sergio Lavandero in
Google Scholar
PubMed Close
,
Ana I Sotelo Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Ana I Sotelo in
Google Scholar
PubMed Close
,
Andrzej Bartke Department of Internal Medicine, Geriatrics Research, Southern Illinois University School of Medicine, Springfield, Illinois, USA

Search for other papers by Andrzej Bartke in
Google Scholar
PubMed Close
,
Patricia A Pennisi Centro de Investigaciones Endocrinológicas ‘Dr. César Bergadá’ (CEDIE), CONICET – FEI – División de Endocrinología, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina

Search for other papers by Patricia A Pennisi in
Google Scholar
PubMed Close
,
Fernando P Dominici Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Fernando P Dominici in
Google Scholar
PubMed Close
, and
Johanna G Miquet Departamento de Química Biológica, Facultad de Farmacia y Bioquímica, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Universidad de Buenos Aires, Buenos Aires, Argentina

Search for other papers by Johanna G Miquet in
Google Scholar
PubMed Close

signaling at the post-receptor level plays a crucial role in GH-induced insulin resistance ( Dominici et al. 2005 , Olarescu & Bollerslev 2016 , Kim & Park 2017 ). Changes in the myocardial sensitivity to insulin action affect cardiac metabolism and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-21-0242
Volume/Issue:
Volume 69: Issue 2
Restricted access
I Robertshaw Department of Obstetrics and Gynecology, University of Cincinnati, West Chester, Ohio, USA
Division of Reproductive Sciences, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

Search for other papers by I Robertshaw in
Google Scholar
PubMed Close
,
F Bian Division of Reproductive Sciences, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

Search for other papers by F Bian in
Google Scholar
PubMed Close
, and
S K Das Division of Reproductive Sciences, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
Perinatal Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

Search for other papers by S K Das in
Google Scholar
PubMed Close

of implantation. The mechanisms by which estrogen transforms a progesterone-primed uterus to the receptive state, activates blastocysts, and initiates implantation are not clearly delineated. The classical estrogen signaling pathway is through

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-15-0300
Volume/Issue:
Volume 56: Issue 3
Free access
Custodia García-Jiménez
Search for other papers by Custodia García-Jiménez in
Google Scholar
PubMed Close
,
Jose Manuel García-Martínez
Search for other papers by Jose Manuel García-Martínez in
Google Scholar
PubMed Close
,
Ana Chocarro-Calvo
Search for other papers by Ana Chocarro-Calvo in
Google Scholar
PubMed Close
, and
Antonio De la Vieja Departamento de Fisiología y Bioquímica, Unidad Funcional de Investigación en Enfermedades Crónicas (UFIEC), Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, 28922 Alcorcon, Madrid, Spain

Search for other papers by Antonio De la Vieja in
Google Scholar
PubMed Close

exogenous), and subsequent increase in insulin-like growth factor 1 (IGF1) signaling. Altered balances of some adipokines may also contribute to an inflammatory state and increased proliferation; iii) chronic inflammation characterized by increased

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-13-0152
Volume/Issue:
Volume 52: Issue 1
Free access
Yefei Pang Marine Science Institute, University of Texas at Austin, Port Aransas, Texas, USA

Search for other papers by Yefei Pang in
Google Scholar
PubMed Close
and
Peter Thomas Marine Science Institute, University of Texas at Austin, Port Aransas, Texas, USA

Search for other papers by Peter Thomas in
Google Scholar
PubMed Close

that multiple mPRs are expressed on the cell membranes of human VSMCs and that both progesterone and 02-0, a selective mPR agonist, but not R5020, a selective PR agonist, rapidly activated MAP kinase and Akt signaling pathways and caused muscle

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-19-0019
Volume/Issue:
Volume 63: Issue 3
Free access
Márcia Faria Serviço de Endocrinologia, Diabetes e Metabolismo do Centro Hospitalar Universitário de Lisboa Norte-Hospital Santa Maria, Lisboa, Portugal
BioISI – Biosystems and Integrative Sciences Institute, Faculdade de Ciências da Universidade de Lisboa, Lisboa, Portugal
Departamento de Genética Humana, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisboa, Portugal

Search for other papers by Márcia Faria in
Google Scholar
PubMed Close
,
Daniela Félix Serviço de Endocrinologia, Diabetes e Metabolismo do Centro Hospitalar Universitário de Lisboa Norte-Hospital Santa Maria, Lisboa, Portugal
ISAMB – Instituto de Saúde Ambiental, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal

Search for other papers by Daniela Félix in
Google Scholar
PubMed Close
,
Rita Domingues Serviço de Endocrinologia, Diabetes e Metabolismo do Centro Hospitalar Universitário de Lisboa Norte-Hospital Santa Maria, Lisboa, Portugal
ISAMB – Instituto de Saúde Ambiental, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal

Search for other papers by Rita Domingues in
Google Scholar
PubMed Close
,
Maria João Bugalho Serviço de Endocrinologia, Diabetes e Metabolismo do Centro Hospitalar Universitário de Lisboa Norte-Hospital Santa Maria, Lisboa, Portugal
Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal

Search for other papers by Maria João Bugalho in
Google Scholar
PubMed Close
,
Paulo Matos BioISI – Biosystems and Integrative Sciences Institute, Faculdade de Ciências da Universidade de Lisboa, Lisboa, Portugal
Departamento de Genética Humana, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisboa, Portugal

Search for other papers by Paulo Matos in
Google Scholar
PubMed Close
, and
Ana Luísa Silva Serviço de Endocrinologia, Diabetes e Metabolismo do Centro Hospitalar Universitário de Lisboa Norte-Hospital Santa Maria, Lisboa, Portugal
ISAMB – Instituto de Saúde Ambiental, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal

Search for other papers by Ana Luísa Silva in
Google Scholar
PubMed Close

molecular ‘switches’ that regulate signaling pathways involved in processes such as gene expression, cell proliferation and cell migration ( Heasman & Ridley 2008 ). An alternative splicing event leads to the generation of RAC1b, a fast activating splice

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-19-0195
Volume/Issue:
Volume 63: Issue 4
Restricted access
I K Lund Signal Transduction, Novo Nordisk A/S, DK-2880 Bagsværd, Denmark
MedChem Research II, Novo Nordisk A/S, DK-2760 Måløv, Denmark
Steno Diabetes Center, Niels Steensens Vej 6, DK-2820 Gentofte, Denmark

Search for other papers by I K Lund in
Google Scholar
PubMed Close
,
J A Hansen Signal Transduction, Novo Nordisk A/S, DK-2880 Bagsværd, Denmark
MedChem Research II, Novo Nordisk A/S, DK-2760 Måløv, Denmark
Steno Diabetes Center, Niels Steensens Vej 6, DK-2820 Gentofte, Denmark

Search for other papers by J A Hansen in
Google Scholar
PubMed Close
,
H S Andersen Signal Transduction, Novo Nordisk A/S, DK-2880 Bagsværd, Denmark
MedChem Research II, Novo Nordisk A/S, DK-2760 Måløv, Denmark
Steno Diabetes Center, Niels Steensens Vej 6, DK-2820 Gentofte, Denmark

Search for other papers by H S Andersen in
Google Scholar
PubMed Close
,
N P H Møller Signal Transduction, Novo Nordisk A/S, DK-2880 Bagsværd, Denmark
MedChem Research II, Novo Nordisk A/S, DK-2760 Måløv, Denmark
Steno Diabetes Center, Niels Steensens Vej 6, DK-2820 Gentofte, Denmark

Search for other papers by N P H Møller in
Google Scholar
PubMed Close
, and
N Billestrup Signal Transduction, Novo Nordisk A/S, DK-2880 Bagsværd, Denmark
MedChem Research II, Novo Nordisk A/S, DK-2760 Måløv, Denmark
Steno Diabetes Center, Niels Steensens Vej 6, DK-2820 Gentofte, Denmark

Search for other papers by N Billestrup in
Google Scholar
PubMed Close

hypothalamus, through which it exerts its key regulatory role by controlling the overall energy homeostasis, i.e. induction of reduced food intake and promotion of weight loss ( Ahima & Flier 2000 , Korner & Aronne 2003 ). Defective leptin signalling due to

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.01694
Volume/Issue:
Volume 34: Issue 2
Free access
Gunnar Kleinau Institute of Experimental Pediatric Endocrinology (IEPE), Charité-Universitätsmedizin, Berlin, Germany

Search for other papers by Gunnar Kleinau in
Google Scholar
PubMed Close
,
Anne Müller Institute of Experimental Pediatric Endocrinology (IEPE), Charité-Universitätsmedizin, Berlin, Germany

Search for other papers by Anne Müller in
Google Scholar
PubMed Close
, and
Heike Biebermann Institute of Experimental Pediatric Endocrinology (IEPE), Charité-Universitätsmedizin, Berlin, Germany

Search for other papers by Heike Biebermann in
Google Scholar
PubMed Close

G-protein-coupled receptors The importance of GPCRs Physiological functions such as development, growth, behavior, learning, emotions, senses and aging are strongly dependent on the control of endocrine circuits. Hormonal signals exert

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-16-0049
Volume/Issue:
Volume 57: Issue 1
Free access
Dhivya Kumar Departments of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, Connecticut, USA

Search for other papers by Dhivya Kumar in
Google Scholar
PubMed Close
,
Richard E Mains Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut, USA

Search for other papers by Richard E Mains in
Google Scholar
PubMed Close
, and
Betty A Eipper Departments of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, Connecticut, USA
Department of Neuroscience, University of Connecticut Health Center, Farmington, Connecticut, USA

Search for other papers by Betty A Eipper in
Google Scholar
PubMed Close

, cloning, and structural/mechanistic studies focused on PAM and then expanded to include cell biological studies on secretory granule biogenesis, retrograde signaling from the granule lumen to the nucleus, and the delivery of essential cofactors (ascorbate

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-15-0266
Volume/Issue:
Volume 56: Issue 4
Free access
Antara A Banerjee Division of Structural Biology, National Institute for Research in Reproductive Health (Indian Council of Medical Research), National Institute for Research in Reproductive Health (Indian Council of Medical Research), Jehangir Merwanji Street, Parel, Mumbai 400 012, India

Search for other papers by Antara A Banerjee in
Google Scholar
PubMed Close
,
Madhavi Dupakuntla Division of Structural Biology, National Institute for Research in Reproductive Health (Indian Council of Medical Research), National Institute for Research in Reproductive Health (Indian Council of Medical Research), Jehangir Merwanji Street, Parel, Mumbai 400 012, India

Search for other papers by Madhavi Dupakuntla in
Google Scholar
PubMed Close
,
Bhakti R Pathak Division of Structural Biology, National Institute for Research in Reproductive Health (Indian Council of Medical Research), National Institute for Research in Reproductive Health (Indian Council of Medical Research), Jehangir Merwanji Street, Parel, Mumbai 400 012, India

Search for other papers by Bhakti R Pathak in
Google Scholar
PubMed Close
, and
Smita D Mahale Division of Structural Biology, National Institute for Research in Reproductive Health (Indian Council of Medical Research), National Institute for Research in Reproductive Health (Indian Council of Medical Research), Jehangir Merwanji Street, Parel, Mumbai 400 012, India
Division of Structural Biology, National Institute for Research in Reproductive Health (Indian Council of Medical Research), National Institute for Research in Reproductive Health (Indian Council of Medical Research), Jehangir Merwanji Street, Parel, Mumbai 400 012, India

Search for other papers by Smita D Mahale in
Google Scholar
PubMed Close

downstream signaling pathways, but the exact molecular mechanism remains elusive. The recently solved crystal structure of FSH in complex with the entire ECD of FSHR including the hinge region provides some explanation. FSH interacts with FSHR in a two

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-14-0275
Volume/Issue:
Volume 54: Issue 3
Free access