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Qin He, Dan Mei, Sha Sha, Shanshan Fan, Lin Wang and Ming Dong

regarded as statistically significant (* P  < 0.05; ** P  < 0.01). Results BBR reduces BW, improves glucose tolerance and promotes insulin sensitivity in HFD-fed mice The BW and food intake (kcal/kg/h) of mice fed with HFD were both

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Hongjie Zhang, Jing Li, Xiangying Liang, Yun Luo, Ke Zen and Chen-Yu Zhang

N Holdsworth CD Turner DS 1964 New interpretation of oral glucose tolerance . Lancet 41 20 – 21 . doi:10.1016/S0140-6736(64)90011-X . McIntyre N Holdsworth CD Turner DS 1965 Intestinal factors in the control of insulin

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Jae Hoon Moon, Hyung Jun Kim, Hyun Min Kim, Ae Hee Yang, Byung-Wan Lee, Eun Seok Kang, Hyun Chul Lee and Bong Soo Cha

until analysis. Blood was collected by cardiac puncture and stored at −20 °C for biochemical tests. Oral glucose tolerance test All the rats underwent an OGTT after an overnight fast using 20% glucose solution (2 g/kg). Blood samples were obtained by

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Guoqing Lei, Linxi Chen, Miao Peng, Bolin Zeng, Qiaoxi Yang, Hening Zhai and Geyang Xu

( Madhumitha et al. 2018 , Yan et al. 2018 ). After treatment with streptozotocin (STZ) for induction of diabetes, mice deficient in IL-27 subunit (EBI3 −/− ) or IL-27 receptor subunit (WSX-1 −/− ) showed worsening glucose tolerance and increased immune

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Fabio Malavasi, Silvia Deaglio, Gianluca Zaccarello, Alberto L Horenstein, Antonella Chillemi, Valentina Audrito, Sara Serra, Marina Gandione, Andrea Zitella and Alessandro Tizzani

interplay between NAD + , PARP, CD38 and cADPR ( Okamoto & Takasawa 2002 ). Mice overexpressing CD38 showed higher insulin levels than controls in glucose-tolerance tests, suggesting enhanced release ( Kato et al . 1995 ). The inference was that Ca 2

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Guoying Chang, Rui Yang, Yanan Cao, Aifang Nie, Xuefan Gu and Huiwen Zhang

levels and impaired glucose tolerance ( Gao et al . 2013 ). Islets from Sidt2 −/− mice cultured in vitro produced less insulin when stimulated with a high concentration of glucose or a depolarizing concentration of KCl. Under physiological

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Jan Christiansen, Astrid M Kolte, Thomas v O Hansen and Finn C Nielsen

4402960 is only associated to decreased disposition index in Hispanics. c Impaired glucose tolerance. d Normal glucose tolerance. e T2D. f Increased fasting glucose. g Normal fasting glucose. h Population-based study. i Non-signifcant after Bonferroni

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Ting Xiao, Xiuci Liang, Hailan Liu, Feng Zhang, Wen Meng and Fang Hu

sensitivity and mitochondrial HSP60 level, which resulted in improved glucose tolerance in the adipocytes of ob/ob mice ( Wilson-Fritch et al . 2004 ), suggesting that mitochondrial HSP60, in the UPR mt pathway, may have distinct functions in different

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R Serrano, M Villar, C Martínez, J M Carrascosa, N Gallardo and A Andrés

classically associated with impaired glucose tolerance and/or peripheral insulin resistance ( De Fronzo 1981 , Narimiya et al. 1984 ). Aged Wistar rats are characterized by fasting normoglycemia and normoinsulinemia and show overall insulin resistance as

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Talitha van der Meulen and Mark O Huising

partially compensate for the loss of MAFA ( Artner et al . 2010 ). Nevertheless, these mice display reduced expression of several genes involved in glucose-stimulated insulin secretion and have reduced glucose tolerance ( Zhang et al . 2005 , Artner et