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Chan Soo Shin, Min Jae Jeon, Jae-Yeon Yang, Sun-Ju Her, Dohee Kim, Sang Wan Kim and Seong Yeon Kim

regarding the regulatory element, they exhibit differences in some aspects of gene regulation. For example, 1,25-dihydroxyvitamin D3 inhibits mouse osteocalcin I and II promoters (OG1, OG2) ( Zhang et al. 1997 ), whereas it activates transcription from rat

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Xiaoyang Yang, Yan Jin and Peter A Cattini

-specific gene regulation. The expression of the GH/CS genes is largely under the control of a remote locus control region (LCR), located 14–32 kb upstream of the GH-N promoter and encompassing a total of five hypersensitive sites (HS I–V; Jones et al . 1995

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Michael Wöltje, Beate Tschöke, Verena von Bülow, Ralf Westenfeld, Bernd Denecke, Steffen Gräber and Willi Jahnen-Dechent

% liver-derived. Thus, Ahsg is a major hepatic serum protein. A thorough understanding of Ahsg gene regulation during inflammation and recovery is important for several reasons. A well-documented physiological function of Ahsg is the systemic inhibition of

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P A Sinclair, W J Gilmore, Z Lin, Y Lou and E J Squires

and Disposition 30 997 –1004. Echchgadda I , Song CS, Oh TS, Cho SH, Rivera OJ & Chatterjee B 2004 Gene regulation for the senescence marker protein DHEA-sulfotransferase by the xenobiotic-activated nuclear pregnane X

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F M Fioretti, A Sita-Lumsden, C L Bevan and G N Brooke

.2005.05821.x ). Beato M 1989 Gene regulation by steroid hormones . Cell 56 335 – 344 . ( doi:10.1016/0092-8674(89)90237-7 ). Birrell SN Bentel JM Hickey TE Ricciardelli C Weger MA Horsfall DJ Tilley WD 1995 Androgens induce

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Christer M Bäck, Stefanie Stohr, Eva A M Schäfer, Heike Biebermann, Ingrid Boekhoff, Andreas Breit, Thomas Gudermann and Thomas R H Büch

TSHR is largely unknown. A well-established mechanism of TSHR-induced gene regulation comprises G s - and cAMP-dependent activation of PKA and subsequent cAMP-responsive element-binding protein (CREB) binding to cAMP-responsive promoter elements. Of

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Laure Quignodon, Carmen Grijota-Martinez, Emmanuel Compe, Romain Guyot, Nathalie Allioli, David Laperrière, Robert Walker, Paul Meltzer, Sylvie Mader, Jacques Samarut and Frédéric Flamant

in cerebellum, the present study strongly suggests that the actual number of direct transcriptional TH targets is much more limited than in other tissues. It seems therefore that gene regulation by TH in the developing cerebellum has to be tightly

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Lykke Blaabjerg, Gitte L Christensen, Masahito Matsumoto, Talitha van der Meulen, Mark O Huising, Nils Billestrup and Wylie W Vale

NFκB-mediated gene regulation. As expected, both IL1β and TNFα significantly increased NFκB promoter activity in INS-1 cells ( Fig. 4 b). The cells pre-treated with oCRF exhibited lesser cytokine-mediated increases in promoter activity, indicating that

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Alison L Hagemeister, Jeffrey D Kittilson, Heather E Bergan and Mark A Sheridan

development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation . Pharmacological Reviews 56 291 – 330 . doi:10.1124/pr.56

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Changxue Lu and Sheue-Yann Cheng

mechanisms that may account for the crosstalk at the gene regulation level ( Fig. 3 ). Several lines of evidence support the notion that there is direct competition between PPARs and TRs for HRE binding and/or partnership with RXR. Moreover, the differential