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William J Stanley, Prerak M Trivedi, Andrew P Sutherland, Helen E Thomas and Esteban N Gurzov

M Cardozo AK Eizirik DL 2009 Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis . Cell Death and Differentiation 16 1539 – 1550 . ( doi:10.1038/cdd.2009

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Ciro Menale, Maria Teresa Piccolo, Grazia Cirillo, Raffaele A Calogero, Alfonso Papparella, Luigi Mita, Emanuele Miraglia Del Giudice, Nadia Diano, Stefania Crispi and Damiano Gustavo Mita

.1161/CIRCULATIONAHA.106.647503 ). Yang R Barouch LA 2007 Leptin signaling and obesity: cardiovascular consequences . Circulation Research 101 545 – 559 . ( doi:10.1161/CIRCRESAHA.107.156596 ). Zha BS Zhou H 2012 ER stress and lipid metabolism in

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Laura Marroquí, Alejandro Gonzalez, Patricia Ñeco, Ernesto Caballero-Garrido, Elaine Vieira, Cristina Ripoll, Angel Nadal and Ivan Quesada

-deficient type 1 diabetic rodents thrive without insulin . PNAS 105 14070 – 14075 . doi:10.1073/pnas.0806993105 . Zhang X Zhang G Zhang H Karin M Bai H Cai D 2008 Hypothalamic IKKβ/NF-kappaB and ER stress link overnutrition to energy

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Sehee Kim, Chanyang Kim and Seungjoon Park

Y Li J Li S Li Y Wang X Liu B Fu Q Ma S 2015 Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK

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Björn Hansson, Sebastian Wasserstrom, Björn Morén, Vipul Periwal, Petter Vikman, Samuel W Cushman, Olga Göransson, Petter Storm and Karin G Stenkula

215) Yang L Li P Fu SN Calay ES Hotamisligil GS 2010 Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance . Cell Metabolism 11 467 – 478 . ( https://doi.org/10.1016/j.cmet.2010.04.005 ) 10.1016/j

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Edward T Bagu and Manuela M Santos

Montosi G Zhang K Lamberti I Duncan SA Kaufman RJ Pietrangelo A 2009 ER stress controls iron metabolism through induction of hepcidin . Science 325 877 – 880 . doi:10.1126/science.1176639 . Veljkovic J Hansen U 2004 Lineage

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Ting-Ting Zhou, Fei Ma, Xiao-Fan Shi, Xin Xu, Te Du, Xiao-Dan Guo, Gai-Hong Wang, Liang Yu, Vatcharin Rukachaisirikul, Li-Hong Hu, Jing Chen and Xu Shen

– R106 . ( doi:10.1530/JOE-15-0447 ) 10.1530/JOE-15-0447) Ansari N Hadi-Alijanvand H Sabbaghian M Kiaei M Khodagholi F 2014 Interaction of 2-APB, dantrolene, and TDMT with IP3R and RyR modulates ER stress-induced programmed

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Pilar Argente-Arizón, Santiago Guerra-Cantera, Luis Miguel Garcia-Segura, Jesús Argente and Julie A Chowen

al . 2010 ) in addition to endoplasmic reticulum (ER) stress ( Gregor & Hotamisligil 2007 ). The effects of long-chain saturated FAs are seen in both astrocytes and microglia, where they induce the release of inflammatory molecules. In contrast, this

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Carla Caruso, Lila Carniglia, Daniela Durand, Teresa N Scimonelli and Mercedes Lasaga

-gut-adipose-tissue communication pathways at a glance . Disease Models & Mechanisms 5 583 – 587 . ( doi:10.1242/dmm.009902 ). Zhang X Zhang G Zhang H Karin M Bai H Cai D 2008 Hypothalamic IKKβ/NF-kappaB and ER stress link overnutrition to energy imbalance and

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G A Martens, E Motté, G Kramer, G Stangé, L W Gaarn, K Hellemans, J H Nielsen, J M Aerts, Z Ling and D Pipeleers

mRNA expression by ER stress imposed during lengthy isolation procedures ( Marselli et al . 2009 ). We confirmed this but also reported that LCM significantly increases bias by contaminating exocrine acinar cells ( Martens et al . 2011 ); evidently