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Matthew L Rise, Susan E Douglas, Dionne Sakhrani, Jason Williams, K Vanya Ewart, Marlies Rise, William S Davidson, Ben F Koop and Robert H Devlin

B ). GRPs are endoplasmic reticulum stress-associated proteins that protect cells against damage during changing environmental conditions ( Ko et al. 2002 ). GRP genes are induced by various stresses that disrupt endoplasmic reticulum (ER) function

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Alessandro Peri and Mario Serio

et al . 2000 ). With regard to its biological effects, seladin-1 was originally found to confer resistance against β-amyloid and oxidative stress-induced apoptosis and to effectively inhibit the activation of caspase-3, a key mediator of the apoptotic

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Edwin J W Geven, Folkert Verkaar, Gert Flik and Peter H M Klaren

avian pituitary thyrotropes (reviewed by De Groef et al. (2006 )). The principal action of hypothalamic CRH in teleosts is the regulation of the stress response ( Huising et al. 2004 , Flik et al. 2006 ). In teleostean fishes, that lack a

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Bo Zhou, Huixia Li, Jiali Liu, Lin Xu, Qinyue Guo, Hongzhi Sun and Shufang Wu

-mediated activation of Erk1/2 and Akt signaling and protection against apoptosis in response to ER-stress ( Li et al . 2014 ). Autophagy induction is an indirect message that protein synthesis is in suspended state, and it is possible that it could benefit in

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Qingling Huang, Elena Timofeeva and Denis Richard

1995 , Buwalda et al. 1997 ). Homeostasis-threatening (stressful) conditions strongly affect the expression of CRF in the PVN. The pattern of CRF activation in the PVN depends on the nature of the applied stresses. Psychological or

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Sehee Kim, Chanyang Kim and Seungjoon Park

Y Li J Li S Li Y Wang X Liu B Fu Q Ma S 2015 Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK

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Yohann Mérot, François Ferrière, Edith Debroas, Gilles Flouriot, Dominique Duval and Christian Saligaut

corresponding expression vectors. Using this approach, we demonstrated that ERα-mediated effects of estrogens on the transcriptional activity of estrogen target reporter genes, on the NGF-induced neurite sprouting or on cell survival to oxidative stress require

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Chanchal Gupta and Kulbhushan Tikoo

of ER ( Tamir et al . 2002 ) and induces its phosphorylation at serine 118 and 167 ( Weitsman et al . 2009 ). Earlier, Chakrabarti & Davidge (2009) had demonstrated that high glucose-induced oxidative stress alters estrogen-mediated regulation of

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Tarlliza R Nardelli, Emerielle C Vanzela, Keli C Benedicto, Flora Brozzi, André Fujita, Alessandra K Cardozo, Décio L Eizirik, Antonio C Boschero and Fernanda Ortis

reticulum (ER) stress (via NO production in the case of rat beta cells) and cell death ( Cardozo et al . 2001 a , Darville et al . 2004 ). The canonical process of NFκB activation is initiated by the phosphorylation of the inhibitor of kappa B ( IkB

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Agua Sobrino, Pilar J Oviedo, Susana Novella, Andrés Laguna-Fernandez, Carlos Bueno, Miguel Angel García-Pérez, Juan J Tarín, Antonio Cano and Carlos Hermenegildo

(MPP), or the ER antagonist (ICI 182 780), all of them from Tocris Bioscience (Ellisville, MI, USA), were obtained by successive dilutions of a stock solution with DMSO. Control cells were exposed to the same vehicles (<0.1% ethanol or 0.1% DMSO