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Gerald Thiel, Isabelle Müller and Oliver G Rössler

impaired glucose tolerance ( Uchida et al . 2011 ). TRPM5 channels are important constituents of Ca 2 + -activated cation current in β-cells. Correspondingly, reduced channel activity could be measured in β-cells of TRPM5-deficient mice ( Colsoul et al

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Huixia Li, Zhuanmin Zhang, Dongxu Feng, Lin Xu, Fang Li, Jiali Liu, Xinxin Jin, Zhuang Qian, Xiaomin Kang and Hongzhi Sun

. Metabolic tests Glucose tolerance testing (GTT) was performed after the mice were fasted overnight. A total of 2 g/kg glucose was administrated through an ip injection, and blood glucose was measured at the indicated time points. Insulin tolerance testing

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L J Moran, P A Mundra, H J Teede and P J Meikle

intima media wall thickness, presence of carotid plaque and increased coronary artery calcification ( Meyer et al . 2005 a , b , Toulis et al . 2011 ). They also have an increased prevalence of impaired glucose tolerance (IGT) and type 2 diabetes

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Ciro Menale, Maria Teresa Piccolo, Grazia Cirillo, Raffaele A Calogero, Alfonso Papparella, Luigi Mita, Emanuele Miraglia Del Giudice, Nadia Diano, Stefania Crispi and Damiano Gustavo Mita

hypothesize that BPA could influence PI3K/Akt signaling. The data of this study agrees well with previous studies that show that GPR30 knockout mice displayed impaired glucose tolerance, reduced body growth, and increased body weight ( Martensson et al . 2009

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Marloes Dekker Nitert, Cecilia L F Nagorny, Anna Wendt, Lena Eliasson and Hindrik Mulder

secretion is defective in the pre-diabetic stage of impaired glucose tolerance ( Hosker et al . 1989 , Tripathy et al . 2000 , Abdul-Ghani et al . 2006 ), and an absolute decompensation of β-cell function characterises the transition to mild diabetes

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H Roger Lijnen and Ilse Scroyen

, several studies have suggested a link between the VEGF/VEGF-R2 pathway and insulin sensitivity and glucose tolerance ( Elias et al . 2012 , Wada et al . 2010 ). In this study, we have investigated whether DC101, a VEGF-R2 blocking MAB ( Bocci et al

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Isadora C Furigo, Pryscila D S Teixeira, Paula G F Quaresma, Naira S Mansano, Renata Frazão and Jose Donato Jr

glucose tolerance and hyperinsulinemia in a glucose tolerance test ( Landgraf et al. 1977 , Tuzcu et al. 2009 ). Bromocriptine, which suppresses PRL, improves glucose tolerance and decreases insulin levels in humans ( Landgraf et al. 1977

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Hyon-Seung Yi, Joon Young Chang and Minho Shong

diabetic nephropathy ( Huang et al . 2006 ). Muscle- or liver-specific deletion of mitochondrial flavoprotein apoptosis inducing factor results in OxPhos deficiency, but leads to the improvement of glucose tolerance and insulin sensitivity in mice

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Liping Luo, Wanxiang Jiang, Hui Liu, Jicheng Bu, Ping Tang, Chongyangzi Du, Zhipeng Xu, Hairong Luo, Bilian Liu, Bo Xiao, Zhiguang Zhou and Feng Liu

control, mice were injected with vehicle (1% DMSO in 150 mM dextrose). For glucose tolerance tests (GTT) and insulin tolerance tests (ITT), 8-week-old male mice were used directly, or were fed a normal diet (ND) or a HFD (60% fat, 20% carbohydrate, 20

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Edra London, Maria Nesterova and Constantine A Stratakis

protein, fat and carbohydrate. Weight gain, adiposity and glucose tolerance Mice were weighed at baseline and then weekly at 09:00 h during the experimental period and at time of killing. Body composition was measured at the conclusion of the 14