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Gioia Altobelli

149 . doi:10.1093/bioinformatics/btl223 . Fraser P Bickmore W 2007 Nuclear organization of the genome and the potential for gene regulation . Nature 447 413 – 417 . doi:10.1038/nature05916 . Gazdag E Santenard A Ziegler-Birling C

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Diego Russo, Giuseppe Damante, Efisio Puxeddu, Cosimo Durante and Sebastiano Filetti

points of this review, however, are the roles played by epigenetic changes in controlling the differentiation and proliferation of transformed thyrocytes and the anticancer treatment strategies that target these changes. Epigenetic gene regulation Gene

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Magdalena I Suszko and Teresa K Woodruff

not necessary for TGFβ-mediated FSHβ gene regulation. In fact, the siRNA results suggest that Smad3 is important for mediating the TGFβ signal that leads to FSHβ transcription. These data suggest that the gonadotrope cell cannot discriminate between

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Masanori Ito, Tomohiko Urano, Hisahiko Hiroi, Mikio Momoeda, Mayuko Saito, Yumi Hosokawa, Ryo Tsutsumi, Fumiko Zenri, Minako Koizumi, Hanako Nakae, Kuniko Horie-Inoue, Tomoyuki Fujii, Tetsu Yano, Shiro Kozuma, Satoshi Inoue and Yuji Taketani

promoter ( Liang et al . 2006 ). A database search (Match-1.0 Public,, sponsored by BIOBASE) enabled the identification of ten P 4 -responsive elements (PREs) within 3000 bp upstream of the gene, one PRE within 405 bp of intron 1 of the

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D T Furuya, A C Poletto, H S Freitas and U F Machado

2a4 gene regulation, as well as potentially involved mechanisms, are completely obscure. We hypothesize that to modulate glycemic homeostasis the ECS could regulate Slc2a4 gene expression. To address this issue, the present study investigated in 3

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Martien J H Kas, Adrie W Bruijnzeel, Jurgen R Haanstra, Victor M Wiegant and Roger A H Adan

NPY mRNA levels in arcuate nucleus neurons of the hypothalamus, indicating that these highly co-localised neuropeptide systems are also highly co-regulated following fasting. However, we have now provided evidence that NPY and AgRP gene regulation in

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G Pelletier, V Luu-The, S Li, L Ren and F Labrie

R , Müller G & Adamski J 2004 The role of 17 beta-hydroxysteroid dehydrogenases. Molecular and Cellular Endocrinology 218 7 –20. Mitchner NA , Garlick C & Ben-Jonathan N 1998 Cellular distribution and gene

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Tram B Doan, J Dinny Graham and Christine L Clarke

chromatin, co-occurrence of other transcription factor binding, and correspond to cell type-specific gene regulation, whereas ESR1-binding sites shared by multiple cell types are characterized by inaccessible chromatin containing high-affinity estrogen

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Francis Bergeron, Edward T Bagu and Jacques J Tremblay

.1093/nar/17.7.2639 . Li L He S Sun JM Davie JR 2004 Gene regulation by Sp1 and Sp3 . Biochemistry and Cell Biology 82 460 – 471 . doi:10.1139/o04-045 . Lobo MV Arenas MI Alonso FJ Gomez G Bazan E Paino CL Fernandez E Fraile

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Elisabeth Presul, Stefan Schmidt, Reinhard Kofler and Arno Helmberg

Endocrinology 35 283 –292. Wallace AD , Wheeler TT & Young DA 1997 Inducibility of E4BP4 suggests a novel mechanism of negative gene regulation by glucocorticoids. Biochemical and Biophysical Research communications 232 403