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Rebecca H Ritchie, Eser J Zerenturk, Darnel Prakoso and Anna C Calkin

acid substitution, C96Y. This mutation is associated with impaired folding of proinsulin leading to endoplasmic reticulum (ER) stress in pancreatic islets such that Akita mice exhibit progressive loss of beta-cells, which correlates with diabetes

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Xinxin Xiang, Wenjiao An, Changtao Jiang, Jing Zhao, Xian Wang, Guang Sun, Yin Li and Weizhen Zhang

signaling. Inhibition of JNK phosphorylation blocks the effect of LPS on resistin expression. Transcriptional factors such as C/EBP-α, PPAR-γ and CHOP-10 are well-known regulators of resistin and have been implicated in the mediation of ER stress on resistin

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Lai Jin, Chuanhua Li, Rong Li, Zongxing Sun, Xianjun Fang and Shengnan Li

during ER stress-induced insulin-secreting cell apoptosis . Journal of Biological Chemistry 283 34819 – 34832 . ( doi:10.1074/jbc.M807409200 ). Lewis K Li C Perrin MH Blount A Kunitake K Donaldson C Vaughan J Reyes TM Gulyas J

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Ji Chen, Chao Li, Wenjie Liu, Bin Yan, Xiaoling Hu and Fengrui Yang

Research 1090287 . ( https://doi.org/10.1155/2018/1090287 ) Yang ZB Chen WW Chen HP Cai SX Lin JD Qiu LZ 2018b MiR-155 aggravated septic liver injury by oxidative stress-mediated ER stress and mitochondrial dysfunction via targeting Nrf

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Ulas Ozkurede, Rishabh Kala, Cameron Johnson, Ziqian Shen, Richard A Miller and Gonzalo G Garcia

2016 Anti-cancer effect of cap-translation inhibitor 4EGI-1 in human glioma U87 cells: involvement of mitochondrial dysfunction and ER stress . Cellular Physiology and Biochemistry 40 . ( https://doi.org/10.1159/000453158 ) Yi T Kabha E

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Yuumi Ishizuka, Kazuhiro Nakayama, Ayumi Ogawa, Saho Makishima, Supichaya Boonvisut, Atsushi Hirao, Yusaku Iwasaki, Toshihiko Yada, Yoshiko Yanagisawa, Hiroshi Miyashita, Masafumi Takahashi, Sadahiko Iwamoto and Jichi Medical University Promotion Team of a Large-Scale Human Genome Bank for All over Japan

T Onozaki K Hayashi H 2005 TRB3, a novel ER stress-inducible gene, is induced via ATF4–CHOP pathway and is involved in cell death . EMBO Journal 24 1243 – 1255 . ( doi:10.1038/sj.emboj.7600596 ). Ostertag A Jones A Rose AJ Liebert

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Lan Xu, Wenting Wang, Xinyue Zhang, Hanni Ke, Yingying Qin, Li You, Weiping Li, Gang Lu, Wai-Yee Chan, Peter C K Leung, Shidou Zhao and Zi-Jiang Chen

954 – 965 . ( https://doi.org/10.1016/S0015-0282(03)01007-0 ) 14556818 10.1016/S0015-0282(03)01007-0 Wu LL Russell DL Norman RJ Robker RL 2012 Endoplasmic reticulum (ER) stress in cumulus-oocyte complexes impairs pentraxin-3 secretion

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Irene I Lee, Nane C Kuznik, Jaice T Rottenberg, Myles Brown and Andrew C B Cato

Lehmusvaara S Visakorpi T Klocker H Cato ACB Maddalo D 2013 Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis . BMC Cancer 13 96 . ( https://doi.org/10.1186/1471-2407-13-96 ) 23448667 10

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Huan Zhang, Xiuxia Liu, Shanshan Zhou, Ye Jia, Ying Li, Yuguo Song, Junnan Wang and Hao Wu

Shaerzadeh F 2013 Inhibition of phosphorylation of JNK suppresses Abeta-induced ER stress and upregulates prosurvival mitochondrial proteins in rat hippocampus . Journal of Molecular Neuroscience 49 262 – 269 . ( https://doi.org/10.1007/s12031

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Huixia Li, Zhuanmin Zhang, Dongxu Feng, Lin Xu, Fang Li, Jiali Liu, Xinxin Jin, Zhuang Qian, Xiaomin Kang and Hongzhi Sun

Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2alpha-dependent manner . Cell Cycle 14 1893 – 1907 . ( https://doi.org/10.1080/15384101.2015.1041686 ) Liu JL Li HX Zhou B Xu L Kang XM Yang W