Search Results

You are looking at 31 - 40 of 212 items for :

  • glucose tolerance x
Clear All
Free access

James Paterson, Ian R Kelsall and Patricia T W Cohen

. Immunoblot analysis of ACC was performed according to Sakamoto et al . (2005), except that lysates were prepared with the addition of 1 μM microcystin. Glucose and insulin tolerance testing Blood glucose levels were assessed using the AccuChek Blood Glucose

Open access

Yan Zheng and Kevin D Houston

impaired glucose tolerance within 6 months of age ( Martensson et al. 2009 ). Of note, both classical and non-classical estrogen signaling regulates glucose uptake, glucose storage, insulin secretion and has a role in insulin sensitivity ( Brown & Clegg

Free access

Haihua Yang and Linghai Yang

cells show greatly enhanced glucose-stimulated insulin secretion and increased glucose tolerance ( Song et al . 2011 , Hussain et al . 2012 ). More importantly, human patients with heterozygous RIα-inactivating mutation (Carney’s complex) also showed

Free access

Jacques-Antoine Haefliger, Françoise Rohner-Jeanrenaud, Dorothée Caille, Anne Charollais, Paolo Meda and Florent Allagnat

Satin LS Piston DW Benninger RK 2012 Connexin-36 gap junctions regulate in vivo first- and second-phase insulin secretion dynamics and glucose tolerance in the conscious mouse . Diabetes 61 1700 – 1707 . ( doi:10.2337/db11-1312 ). Inada

Free access

Hongjie Zhang, Jing Li, Xiangying Liang, Yun Luo, Ke Zen and Chen-Yu Zhang

N Holdsworth CD Turner DS 1964 New interpretation of oral glucose tolerance . Lancet 41 20 – 21 . doi:10.1016/S0140-6736(64)90011-X . McIntyre N Holdsworth CD Turner DS 1965 Intestinal factors in the control of insulin

Free access

Kayla A Boortz, Kristen E Syring, Lynley D Pound, Huan Mo, Lisa Bastarache, James K Oeser, Owen P McGuinness, Joshua C Denny and Richard M O’Brien

interbreeding of heterozygous (HET) mice. Intraperitoneal glucose tolerance tests Intraperitoneal glucose tolerance tests (IPGTTs) were performed on ~22-week-old male mice as previously described ( Pound et al . 2012 ). Phenotypic analysis of

Free access

Ping Li, Yan Hao, Feng-Hui Pan, Min Zhang, Jian-Qiang Ma and Da-Long Zhu

, USA). Systolic blood pressure was measured in conscious animals using a tail-cuff blood pressure analyzer (BP-98A; Softron Corporation, Japan) every 2 weeks. To estimate glucose tolerance, at 17 weeks of age, mice were fasted for 16 h, and a basal

Free access

Darren S D Martin, Siobhán Leonard, Robert Devine, Clara Redondo, Gemma K Kinsella, Conor J Breen, Victoria McEneaney, Mary F Rooney, Tim S Munsey, Richard K Porter, Asipu Sivaprasadarao, John C Stephens and John B C Findlay

. The mice then underwent a glucose tolerance test which indicated that those on the high-fat diet indeed had impaired glucose handling abilities (mean AUC values – normal chow 17.64±3.7, high-fat diet 36.08±2.9). This latter HFD group was then sub

Free access

Maria Sörhede Winzell and Bo Ahrén

. Journal of Biological Chemistry 272 21201 – 21206 . Pacini G Thomaseth K Ahrén B 2001 Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice . American Journal of Physiology Endocrinology and Metabolism 281

Free access

Patrizia Morera, Loredana Basiricò, Kenji Hosoda and Umberto Bernabucci

rectal temperature (RT) were recorded daily. On 0 and 5 days, six animals from each group were used to perform a glucose tolerance test (GTT). At the beginning (day 0) and after 2 and 5 days of the experimental period, six animals from each group were