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Eva Tudurí, Monica Imbernon, Rene Javier Hernández-Bautista, Marta Tojo, Johan Fernø, Carlos Diéguez and Rubén Nogueiras

.1 µmol/kg, i.p. Increased GSIS and improved glucose tolerance McKillop et al . (2016) GLP-1 −/− mice Abn-CBD Agonist 2.5, >30, >30 μM 0.1 µmol/kg, i.p. No effects on GSIS or glucose tolerance McKillop et al . (2016) GPR

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Ahter D Sanlioglu, Bahri Karacay, Mustafa Kemal Balci, Thomas S Griffith and Salih Sanlioglu

Obesity and inflammation Diabetes is the third most common disease and fourth leading cause of death in the world ( Tabak et al . 2012 ). Insulin resistance, impaired glucose tolerance, and excessive glucagon secretion are the prominent features of

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James Paterson, Ian R Kelsall and Patricia T W Cohen

Monitoring System (Roche Diagnostics). Glucose tolerance tests were performed on mice after a 12–14 h overnight fast. Mice were injected intraperitoneally with 2 mg d -glucose/g, and blood glucose levels were determined immediately before and at 15, 30, 60

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Kayla A Boortz, Kristen E Syring, Lynley D Pound, Huan Mo, Lisa Bastarache, James K Oeser, Owen P McGuinness, Joshua C Denny and Richard M O’Brien

interbreeding of heterozygous (HET) mice. Intraperitoneal glucose tolerance tests Intraperitoneal glucose tolerance tests (IPGTTs) were performed on ~22-week-old male mice as previously described ( Pound et al . 2012 ). Phenotypic analysis of

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J Bian, X M Bai, Y L Zhao, L Zhang and Z J Liu

food intake was measured daily. The BW was recorded daily for 4 weeks, after which it was measured weekly. After 8 weeks of the diet, glucose tolerance tests were performed. The animals were fasted overnight and glucose was administered

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Jian-Hua Chen, Maria Segni, Felicity Payne, Isabel Huang-Doran, Alison Sleigh, Claire Adams, UK10K Consortium, David B Savage, Stephen O'Rahilly, Robert K Semple and Inês Barroso

. 2006 ). Other analytes were determined in accredited clinical diagnostic laboratories of the referring hospital. For oral glucose tolerance testing, 1.75 g glucose/kg was administered after a 10 h fast and blood samples taken at the times indicated for

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Xinxin Xiang, Wenjiao An, Changtao Jiang, Jing Zhao, Xian Wang, Guang Sun, Yin Li and Weizhen Zhang

Cell Signaling Technology (Beverly, MA, USA). IRDye-conjugated affinity purified anti-rabbit, anti-mouse and anti-goat IgGs were purchased from Rockland (Gilbertsville, PA, USA). Glucose tolerance test For the oral glucose tolerance tests (OGTTs), mice

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Haoyong Yu, Mingliang Zhang, Yunqin Ma, Junxi Lu, Jiemin Pan, Pan Pan, Haibing Chen and Weiping Jia

). Serum glucose levels were subsequently measured at 0, 15, 30, 60 and 90 min after insulin injection using the ACCU-CHEK glucometer. Glucose tolerance test (GTT) was performed on the 9th week of treatment 0, 30, 60, and 90 min after 1 g/kg glucose

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Haihua Yang and Linghai Yang

cells show greatly enhanced glucose-stimulated insulin secretion and increased glucose tolerance ( Song et al . 2011 , Hussain et al . 2012 ). More importantly, human patients with heterozygous RIα-inactivating mutation (Carney’s complex) also showed

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Anthony L Albiston, Mauricio Cacador, Puspha Sinnayah, Peta Burns and Siew Yeen Chai

et al . 2008 ). Glucose handling after an oral glucose challenge The effect of IRAP inhibitor HFI-419 on whole animal glucose handling was evaluated after an oral glucose tolerance test (OGTT) in male Sprague–Dawley rats. Twelve rats were