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Andrea Armani, Vincenzo Marzolla, Andrea Fabbri and Massimiliano Caprio

and pathophysiology. Pharmacological MR antagonism has been shown to counteract dysfunctional metabolism of adipose tissue ( Guo et al . 2008 , Hirata et al . 2009 , Wada et al . 2010 ). Remarkably, conversion of white into brown adipose tissue, a

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J Bian, X M Bai, Y L Zhao, L Zhang and Z J Liu

149 1049 – 1055 . ( doi:10.1210/en.2007-1018 ). Baile CA Bella-Fera M Martin RJ 2000 Regulation of metabolism and body fat mass by leptin . Annual Review of Nutrition 20 105 – 127 . ( doi:10.1146/annurev.nutr.20.1.105 ). Bjorbaek C

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Karin J Bosma, Mohsin Rahim, Kritika Singh, Slavina B Goleva, Martha L Wall, Jing Xia, Kristen E Syring, James K Oeser, Greg Poffenberger, Owen P McGuinness, Anna L Means, Alvin C Powers, Wen-hong Li, Lea K Davis, Jamey D Young and Richard M O’Brien

unlikely to directly affect metabolism in these tissues. Figure 1 Comparison of tissue-specific G6pc isoform expression in male mice. Comparison of G6pc1 (Panel A), G6pc2 (Panel B), G6pc3 (Panel C) and Slc37a4 (Panel D) expression in brain

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Ulrich Schweizer and Clemens Steegborn

Introduction Thyroid hormones (THs) are essential for developmental processes, growth, and the regulation of energy metabolism ( Tata 1968 , Bianco & Kim 2006 , Mullur et al . 2014 ). In the thyroid gland, tyrosine residues within thyroglobulin

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Luis Varela, María J Vázquez, Fernando Cordido, Rubén Nogueiras, Antonio Vidal-Puig, Carlos Diéguez and Miguel López

investigation. Hypothalamic fatty acid metabolism: a housekeeping pathway modulating whole-body energy balance Fatty acids are derived either from the diet or by de novo synthesis. The basic pathway for de novo fatty acid synthesis is summarized in Fig. 2

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Yan Zheng and Kevin D Houston

.18632/oncotarget.22552 ) 29312586 Barton M Prossnitz ER 2015 Emerging roles of GPER in diabetes and atherosclerosis . Trends in Endocrinology and Metabolism 26 . ( https://doi.org/10.1016/j.tem.2015.02.003 ) Brown LM Clegg DJ 2010 Central

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Fabien Duval, Esther Dos Santos, Benoît Maury, Valérie Serazin, Khadija Fathallah, François Vialard and Marie-Noëlle Dieudonné

in human EnSCs ( Duval et al. 2017 ). Considering the importance of adiponectin in the control of glucose metabolism, we aimed to study the in vitro effect of human recombinant adiponectin on glycogen synthesis and trafficking at the human fetal

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Eva Tudurí, Monica Imbernon, Rene Javier Hernández-Bautista, Marta Tojo, Johan Fernø, Carlos Diéguez and Rubén Nogueiras

attracted more attention over the last years is undoubtedly its ability to modulate energy metabolism. The best-characterized endocannabinoids are N-arachidonoylethanolamide (anandamide, AEA) and 2-arachidonoylglycerol (2-AG), which exert their effects by

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Philip A Gruppuso and Jennifer A Sanders

administration of thyroxine, but not by growth hormone. Similar results were obtained for tyrosine aminotransferase, a critical enzyme in amino acid metabolism. These studies were interpreted at the time as indicating that cAMP-mediated hormones are responsible

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Tram B Doan, J Dinny Graham and Christine L Clarke

tumorigenesis and progression including regulation of the circadian clock, metabolism, migration and metastasis. In this review, we will discuss evidence for these emerging functional roles of NRs in breast cancer, as well as new insights into the molecular