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Qin He, Dan Mei, Sha Sha, Shanshan Fan, Lin Wang and Ming Dong

isoquinoline alkaloid isolated from Berberis vulgaris L, has been widely used in traditional Chinese medicine to treat diarrhoea, insulin resistance, inflammation and gastrointestinal disorders. Recently, there is fast-growing concerns in exploring its

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Rihua Zhang, Dongming Su, Weidong Zhu, Qiong Huang, Menglan Liu, Yi Xue, Yuanyuan Zhang, Dong li, Allan Zhao and Yun Liu

models have shown that oophorectomy results in obesity, altered fat distribution, adipose tissue inflammation, and development of fatty liver ( Rogers et al . 2009 , Stubbins et al . 2012 ). Estrogen therapy is believed to have beneficial effects on

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Ashley A Able, Allison J Richard and Jacqueline M Stephens

protein 1 (MCP1) and tumor necrosis factor-alpha (TNFα), indicating that DBC1 may influence adipocyte inflammation ( Moreno-Navarrete et al. 2015 b ). DBC1 has also been implicated in senescence of preadipocytes as loss of DBC1 protects again cellular

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Michael Welsh, Maria Jamalpour, Guangxiang Zang and Björn Åkerblom

detected as selectively present in focal adhesions ( Winograd-Katz et al . 2014 ). SHB and inflammation A characteristic feature of SHB based on data obtained from the Shb knockout mouse is its involvement in inflammatory processes ( Arbiser 2015 ). An

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Ying Chen, Hua Ni, Xing-Hong Ma, Shi-Jun Hu, Li-Ming Luan, Gang Ren, Yue-Chao Zhao, Shi-Jie Li, Hong-Lu Diao, Xiu Xu, Zhen-Ao Zhao and Zeng-Ming Yang

-implantation site on day 5 of pregnancy (Fig. 3K ), and on day 5 of pseudopregnancy (Fig. 3L ). T-cell immunoglobulin and mucin domain containing 2 ( Timd2 ) is critical for the regulation of Th2 responses during autoimmune inflammation ( Chakravarti et al. 2005

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Lai Jin, Chuanhua Li, Rong Li, Zongxing Sun, Xianjun Fang and Shengnan Li

mediators including TNFα and IL1β are natural stimulators of cPLA 2 gene expression ( Dolan-O'Keefe et al . 2000 ). CRH family peptides are closely associated with inflammation ( Webster et al . 1998 ). In order to investigate whether CRH family peptides

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Isabel Castro, Leah Quisenberry, Rosa-Maria Calvo, Maria-Jesus Obregon and Joaquin Lado-Abeal

responsible for the decrease in TH receptor β1 ( THRB1 ) expression during inflammation in rodents ( Kwakkel et al . 2006 ). Limited access to human tissues is an obstacle for understanding the effects of NTIS on patients and uncovering the molecular

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Andrea Armani, Vincenzo Marzolla, Andrea Fabbri and Massimiliano Caprio

pathophysiological contexts, including metabolic syndrome, oxidative stress, stress adaptability, inflammation and more. In this context, several research groups identified the adipocyte as a novel cellular model for investigating the function of MR in the

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Zhao Yang, Zhi-Li Huang and Ya-Xiong Tao

cardiovascular function ( Versteeg et al . 1998 , Mioni et al . 2003 ), natriuresis ( Ni et al . 2006 , Chandramohan et al . 2009 ), and inflammation ( Catania et al . 2004 , Getting et al . 2006 , Getting et al . 2008 ). The MC3R, together with MC4R

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Marc Simard, Caroline Underhill and Geoffrey L Hammond

thought to promote the delivery of cortisol to sites of inflammation ( Hammond et al . 1990 , Lin et al . 2009 ). A metalloprotease (LasB), secreted by the pathogen Pseudomonas aeruginosa, may also contribute to the localized release of cortisol from