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S Najib and V Sánchez-Margalet

. Current Biology 8 69 –81. Avruch J 1998 Insulin signal transduction through protein kinase cascades. Molecular and Cell Biochemistry 182 31 –48. Bhalla US , Ram PT & Iyengar R 2002 MAP

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M R Silver and S A Sower

. Arora KK , Sakai A & Catt KJ 1995 Effects of second intracellular loop mutations on signal transduction and internalization of the gonadotropin-releasing hormone receptor. Journal of Biological Chemistry 270 22820 –22826

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M Blumenstein, J A Keelan, J M Bowen-Shauver and M D Mitchell

parturition, both at term and preterm, has been likened to an inflammatory reaction/process ( Bowen et al. 2002 ). SOCS proteins regulate signal transduction by several cytokines that have been reported to be present and affect human gestational tissues

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J H Li, F Sicard, M A Salam, M Baek, J LePrince, H Vaudry, K Kim, H B Kwon and J Y Seong

, Richard et al. 2001 ). The signal transduction pathways associated with NTRs have been studied in various cell lines. Activation of rat NTR1 (rNTR1) induces an increase in inositol trisphosphate (IP 3 ) and Ca 2+ mobilization through an

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T Zhang and M S Roberson

-specific JNK and MEK1/2 antibodies were purchased from Cell Signaling (Beverly, MA, USA). The MEK1 antibody was from Transduction Laboratories (Lexington, KY, USA). Phorbol 12-myristate 13-acetate (PMA) and the GnRH agonist (GnRHa) buserelin were purchased from

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J Jason Collier, Tim E Sparer, Michael D Karlstad and Susan J Burke

binding have not been fully elucidated, there are some clues about CXCR3 signal transduction cascades that are informative. For example, the differential downstream signaling is due, at least in part, to differential Gα subunit usage ( Kouroumalis et al

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D Hanson, P G Murray, T Coulson, A Sud, A Omokanye, E Stratta, F Sakhinia, C Bonshek, L C Wilson, E Wakeling, S A Temtamy, M Aglan, E M Rosser, S Mansour, A Carcavilla, S Nampoothiri, W I Khan, I Banerjee, K E Chandler, G C M Black and P E Clayton

determine relative expression of IGFBPs between 3-M cell lines and control fibroblasts. We were unable to detect secreted IGFBP5, so intracellular levels were assessed by immunoblotting. Signal transduction assays We first evaluated the basal protein levels

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Marcio A Figueiredo, Robert T Boyle, Juliana Z Sandrini, Antonio S Varela Junior and Luis F Marins

physiochemical characterization . Journal of Biological Chemistry 266 22645 – 22652 . Lobie PE Wood TJ Sliva D Billestrup N Waters MJ Enberg B Norstedt G 1994 The cellular mechanism of growth hormone signal transduction . Acta Paediatrica

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Yanyan Cao, Yunsheng Li, Jaekyung Kim, Yulin Ren, Klaus Himmeldirk, Yi Liu, Yanrong Qian, Fengming Liu and Xiaozhuo Chen

supporting a passive role for the insulin receptor transmembrane domain in insulin-dependent signal transduction . Journal of Biological Chemistry 266 9829 – 9834 . Gin H Rigalleau V Caubet O Masquelier J Aubertin J 1999 Effects of red wine

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Zhi Zhang, Fang Wang, Bing-jian Wang, Guang Chu, Qunan Cao, Bao-Gui Sun and Qiu-Yan Dai

-antagonist function of adiponectin in our 3D vessel model in order to elucidate the effects of receptors and the underlying signal transduction pathways of adiponectin. Materials and methods Preparation of HUVECs and HUASMCs The present study was approved by the