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Karen Jesus Oliveira, Maria Isabel Chiamolera, Gisele Giannocco, Carmen Cabanelas Pazos-Moura and Tania Maria Ortiga-Carvalho

inhibits the peripheral metabolism of THs mediated by the D1 in the liver. Coffee and caffeine Coffee contains over a thousand components, including many with biological activity, such as caffeine, diterpene alcohols and chlorogenic acid, which are

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Thomas Svava Nielsen, Niels Jessen, Jens Otto L Jørgensen, Niels Møller and Sten Lund

deleterious effects of an excessive daily influx of dietary lipids ( Manolopoulos et al . 2010 ). The regulation and implications of these gender- and depot-specific differences in terms of AT metabolism and signaling has been covered in great detail in a

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Douglas A Gibson, Paul A Foster, Ioannis Simitsidellis, Hilary O D Critchley, Olympia Kelepouri, Frances Collins and Philippa T K Saunders

of oestrogen-primed human endometrial stromal fibroblast (hESF) (reviewed in Gellersen & Brosens 2014 ), we have demonstrated an important role for local (intracrine) steroid metabolism in fine-tuning the cellular differentiation of hESFs ( Gibson

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Elin Swedenborg, Joëlle Rüegg, Sari Mäkelä and Ingemar Pongratz

signaling or by activating other signaling pathways, in particular that of the aryl hydrocarbon receptor (AhR), a receptor involved in the metabolism of many xenobiotic substances. This review focuses on the molecular mechanisms by which EDCs can affect NR

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Patrizia Morera, Loredana Basiricò, Kenji Hosoda and Umberto Bernabucci

cellular functions and reprogramming of cellular metabolism ( Lindquist 1986 ). In contrast to acute HS, the effects of chronic HS on gene expression and cellular metabolism have been studied only to a limited extent ( Zhang et al . 2002 , Bhusari et al

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Lacey M Litchfield and Carolyn M Klinge

Metabolism 23 83 – 89 . ( doi:10.1016/j.tem.2011.10.003 ). Calonge MJ Seoane J Massague J 2004 Opposite Smad and chicken ovalbumin upstream promoter transcription factor inputs in the regulation of the collagen VII gene promoter by transforming

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Umberto Bernabucci, Loredana Basiricò, Patrizia Morera, Nicola Lacetera, Bruno Ronchi and Alessandro Nardone

Introduction Future climate scenarios suggest that higher global mean temperatures could result in marked changes in the frequency of heat waves ( Kattenberg et al . 1996 ). In farm animals, the alteration of energy metabolism and immune response

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I J Bujalska, M Quinkler, J W Tomlinson, C T Montague, D M Smith and P M Stewart

preadipocytes treated with F versus control and OM preadipocytes treated with F versus control. Genes were analysed according to their metabolic function, such as glucocorticoid metabolism, transcription factors, genes involved in growth arrest, extracellular

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Edward T Bagu and Manuela M Santos

GATA (FOG) modulate the tissue-specific transcription of other genes involved in the metabolism of iron, in particular: GATA-1 is a transcriptional enhancer of hemochromatosis ( HFE ; Mura et al . 2004 ) and erythropoietin receptor ( EPOR ; Chiba et

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Amanda M Ackermann and Maureen Gannon

2004 Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice. American Journal of Physiology. Endocrinology and Metabolism 287 E405 –E413. Lu Y