Search Results

You are looking at 1 - 1 of 1 items for

  • Author: Yamil Boo Irizarry x
  • Refine by access: All content x
Clear All Modify Search
Qilin Cao Functional Immunogenomics Unit, Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA

Search for other papers by Qilin Cao in
Google Scholar
PubMed
Close
,
Yamil Boo Irizarry Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA

Search for other papers by Yamil Boo Irizarry in
Google Scholar
PubMed
Close
,
Svetlana Yazhuk Operations and Engineering Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA

Search for other papers by Svetlana Yazhuk in
Google Scholar
PubMed
Close
,
Thai Tran Functional Immunogenomics Unit, Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA

Search for other papers by Thai Tran in
Google Scholar
PubMed
Close
,
Manasi Gadkari Functional Immunogenomics Unit, Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA

Search for other papers by Manasi Gadkari in
Google Scholar
PubMed
Close
, and
Luis Miguel Franco Functional Immunogenomics Unit, Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA

Search for other papers by Luis Miguel Franco in
Google Scholar
PubMed
Close

Glucocorticoids are the cornerstone of immunosuppressive and anti-inflammatory therapy in humans, yet the mechanisms of glucocorticoid immunoregulation and toxicity remain unclear. The response to glucocorticoids is highly cell type-dependent, so translating results from different experimental systems into a better understanding of glucocorticoid effects in humans would benefit from rapid access to high-quality data on the response to glucocorticoids by different cell types. We introduce GCgx, a web application that allows investigators to quickly visualize changes in transcript abundance in response to glucocorticoids in a variety of cells and species. The tool is designed to grow by the addition of datasets based on input from the user community. GCgx is implemented in R and HTML and packaged as a Docker image. The tool and its source code are publicly available.

Restricted access