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D T Furuya, A C Poletto, H S Freitas, and U F Machado

the regulation of lipolysis and energy balance . Journal of the Federation of American Societies for Experimental Biology 19 1 – 27 . doi:10.1096/fj.04-2370com . Kim JB Sarraf P Wright M Yao KM Mueller E Solanes G Lowell BB

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Elin Swedenborg, Joëlle Rüegg, Sari Mäkelä, and Ingemar Pongratz

increased lipolysis and decreased glucose oxidation, both symptoms characteristic of diabetes and obesity ( Hoppe & Carey 2007 ). Yet another example is bisphenol A (BPA), a monomer with strong estrogenic properties, used in its polymeric form as lining of

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M J Watt, R J Southgate, A G Holmes, and M A Febbraio

attenuated, suggesting that mechanisms other than FFA are important for their gene expression. Despite total suppression of lipolysis, NA ingestion at rest increased the mRNA content of PGC1α and PPARα/δ, which was associated with elevated plasma epinephrine

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R Serrano, M Villar, C Martínez, J M Carrascosa, N Gallardo, and A Andrés

lipolysis. Journal of Biological Chemistry 239 375 –385. Ruiz P , Pulido JA, Martinez C, Carrascosa JM, Satrustegui J & Andres A 1992 Effect of aging on the kinetic characteristics of the insulin receptor

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Penny Ahlstrom, Esther Rai, Suharto Chakma, Hee Ho Cho, Palanivel Rengasamy, and Gary Sweeney

Yan W Xia Y Chen X Wang W Zhang J Gao C Peng C Yan F 2016 Branched chain amino acids cause liver injury in obese/diabetic mice by promoting adipocyte lipolysis and inhibiting hepatic autophagy . EBioMedicine 13 157 – 167 . ( doi

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Jae Hoon Moon, Hyung Jun Kim, Hyun Min Kim, Ae Hee Yang, Byung-Wan Lee, Eun Seok Kang, Hyun Chul Lee, and Bong Soo Cha

serum triglycerides by increasing their clearance from the circulation, most likely through increased lipoprotein lipase-mediated lipolysis of VLDLs ( Hanefeld 2009 ). One in vitro study reported that LRP1 is regulated by PPARγ and that rosiglitazone

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Anke Gutgesell, Robert Ringseis, Eileen Schmidt, Corinna Brandsch, Gabriele I Stangl, and Klaus Eder

the mammary gland due to the enhanced expression of Lpl ( Farid et al . 1978 , Grigor et al . 1982 ). Simultaneously, the uptake of NEFA derived mainly from lipolysis in white adipose tissue by fatty acid transporters into the mammary gland as

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Viral Chikani and Ken K Y Ho

availability of metabolic fuels and its capacity to synthesise ATP. The energy synthesis from substrate utilisation in exercising muscle is regulated by nutritional, genetic and hormonal factors as well as physical training. GH stimulates lipolysis during

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Hyon-Seung Yi, Joon Young Chang, and Minho Shong

-sucrose diet-fed mice by sirtuin-mediated UPR mt , triggering an adaptive mitohormesis in the liver of mice ( Gariani et al . 2016 ). The UPR mt induced by skeletal muscle-specific OxPhos deficiency is also associated with enhanced lipolysis and fatty acid

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Yanxia Tang and GuoDong Li

increased plasma levels of free fatty acids (FFAs) resulting from lack of appropriate suppression of adipocyte lipolysis due to insulin resistance and deficiency ( Reaven 1988 , Imrie et al . 2010 ). Furthermore, circulating levels of FFAs are usually