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Yuan Pan, Chong Han, Chunlin Wang, Guohan Hu, Chun Luo, Xiaoqiang Gan, Fenglin Zhang, Yicheng Lu, and Xuehua Ding

, Mochizuki & Okada 2007 , Moss et al . 2008 , Parkin & Harris 2009 ). The proteinase activity of ADAM10 contributes to Alzheimer's disease ( Lammich et al . 1999 , Allinson et al . 2003 ), inflammation, and cancer ( Crawford et al . 2009 , Pruessmeyer

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Yuxiao Tang, Xingjian Cai, Hongwei Zhang, Hui Shen, Wanyin Wang, Zhilei Shen, Wei Gu, Changquan Ling, and Min Li

, that overactivity of the HPA axis is accompanied by impaired physical functions, including growth, metabolism, circulation, reproduction, inflammation and immunity ( Charmandari et al . 2005 , Chrousos & Kino 2007 , Nicolaides et al . 2015 ). The

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Evgeny Weinberg, Tal Maymon, and Miron Weinreb

. International Immunopharmacology 8 679 – 687 . ( doi:10.1016/j.intimp.2008.01.013 ). Graves DT Liu R Alikhani M Al-Mashat H Trackman PC 2006 Diabetes-enhanced inflammation and apoptosis – impact on periodontal pathology . Journal of Dental Research 85 15 – 21

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Chanchal Gupta and Kulbhushan Tikoo

.01, and *** P <0.001 where a vs NG-C, b vs NG-Ins, and c vs HG-C. NG-C, normal glucose control; NG-Ins, normal glucose+insulin; HG-C, high glucose; and HG-Ins, high glucose+insulin. NF-κB is a transcription factor, playing vital role in inflammation, cell

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Shan Song, Duojun Qiu, Fengwei Luo, Jinying Wei, Ming Wu, Haijiang Wu, Chunyang Du, Yunxia Du, Yunzhuo Ren, Nan Chen, Huijun Duan, and Yonghong Shi

to mitigate renal inflammation and fibrosis in a model of renal tubular injury ( Iyer et al . 2009 , Zhuang et al . 2014 ). Existing research demonstrated that NLRP3 protein expression, cleavage of Caspase-1, along with the maturation of IL1B and

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Laura Marroquí, Alejandro Gonzalez, Patricia Ñeco, Ernesto Caballero-Garrido, Elaine Vieira, Cristina Ripoll, Angel Nadal, and Ivan Quesada

islets ↓ IL1 receptor antagonist expression Maedler et al . (2004) Proapoptotic RINm5F ↑ Caspase activity, ↑ expression of  inflammation-related genes Hekerman et al . (2007) Both protective and deleterious effects have been attributed to leptin

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Cheryl A Conover and Claus Oxvig

2012 ). Inflammation is prevalent in tumor tissues ( Szebeni et al . 2017 ). Figure 2 Regulation of PAPP-A in cancer STC inhibits PAPP-A activity, Bikunin inhibits PAPP-A expression, wild-type p53 inhibits PAPP-A expression, mAb-PA inhibits PAPP

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Philippe Huber, Christine Mallet, Elodie Faure, Christine Rampon, Marie-Hélène Prandini, Olivier Féraud, Stéphanie Bouillot, and Isabelle Vilgrain

inflammation, hyperplasia, and neoplasia ( Katoh 2003 ). Of interest, carcinomas and adenomas in human adrenal cortex differ in their angiogenic patterns as visualised by CD34 labelling ( Bernini et al. 2002 ). As VE-cadherin is an important

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Dong Zhao, Jinhua Jia, and Hong Shao

plays an important part in many different physiological and pathological processes, including the growth and differentiation of organism, cell proliferation and tumor, inflammation and endocrine diseases ( Jackson & Levin 2012 ). To date, a great number

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Tristan M Lovell, Russell J Woods, David J Butlin, Kerensa J Brayley, Isaac T Manyonda, Jackie Jarvis, Steve Howell, and Philip J Lowry

proCRF in the plasma contain PC as a PTM suggests that PC plays an important function during pregnancy and may be the reason for the elevated levels of C-reactive protein ( Tjoa 2003 ) and the accompanying inflammation seen in this condition ( Redman et