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Marc Simard, Caroline Underhill, and Geoffrey L Hammond

thought to promote the delivery of cortisol to sites of inflammation ( Hammond et al . 1990 , Lin et al . 2009 ). A metalloprotease (LasB), secreted by the pathogen Pseudomonas aeruginosa, may also contribute to the localized release of cortisol from

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Tarlliza R Nardelli, Emerielle C Vanzela, Keli C Benedicto, Flora Brozzi, André Fujita, Alessandra K Cardozo, Décio L Eizirik, Antonio C Boschero, and Fernanda Ortis

beta cells in the context of inflammation. The findings obtained indicate that PRL exerts an anti-apoptotic role in rat beta cells exposed to pro-inflammatory cytokines potentially through STAT3. PRL induces AKT phosphorylation and consequentially

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Gregory S Y Ong and Morag J Young

basal cardiac MR occupancy by endogenous glucocorticoid is protective against activation. However, in situations of intracellular oxidative stress, such as with inflammation or ischaemia, glucocorticoids can activate the MR ( Rossier et al . 2008

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Shannon E Mullican, Joanna R DiSpirito, and Mitchell A Lazar ) from which this information was collated Receptor Embryonic lethal Whole body mutants Tissue-specific mutants DAX1 (NR0B1) No KO: fertility (males) NR SHP (NR0B2) No KO: fertility; energy expenditure, cholesterol metabolism, hepatic inflammation (diet

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Zhipeng Li, Zhaoshui Shangguan, Yijie Liu, Jihua Wang, Xuejun Li, Shuyu Yang, and Suhuan Liu

. 2012 ), anti-inflammation ( Huang et al . 2012 , Jin et al . 2012 ), and anti-apoptosis ( Liang et al . 2012 , Zhang et al . 2012 ) properties. It has been reported that puerarin improved insulin resistance and glucose tolerance ( Prasain et al

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Dimitrios Doultsinos and Ian Mills

involved in intestinal inflammation and promotes the development of inflammatory disorders when disrupted, as it causes imbalances in the ER homeostatic microenvironment through autophagy or secretion of AGR2 itself ( Maurel et al. 2019 ). Its little

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Ye Zhou, Eric C Bolton, and Jeremy O Jones

prostate inflammation, which causes damage that requires prostate lobe regeneration (and the increased presence of stem cells), are at a greater risk for prostate cancer ( Haverkamp et al . 2008 , Klein & Silverman 2008 , Bardia et al . 2009

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Zodwa Dlamini, Fortunate Mokoena, and Rodney Hull

). Diabetes, alternate splicing and apoptosis Type 1 diabetes is an autoimmune disease, where the immune system carries out an assault on the β-cells of the pancreas, resulting in pancreatic islet inflammation (insulitis) and β-cell apoptosis ( Santin

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Christopher E Wall, Ruth T Yu, Anne R Atkins, Michael Downes, and Ronald M Evans

Introduction Lifestyle interventions such as improving diet and exercise habits can effectively combat many disease symptoms associated with metabolic syndrome, including obesity, hyperglycemia, insulin resistance, inflammation

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Lijuan Yin, Fang Fang, Xinglei Song, Yan Wang, Gaoxiang Huang, Jie Su, Ning Hui, and Jian Lu

cancer therapy of solid malignant tumors because of their beneficial effectiveness in treatment-related edema, inflammation, pain, and electrolyte imbalance ( Rutz 2002 , Rutz & Herr 2004 ). GCs are also given before, during, and after chemotherapy of