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Zhao Yang, Zhi-Li Huang, and Ya-Xiong Tao

cardiovascular function ( Versteeg et al . 1998 , Mioni et al . 2003 ), natriuresis ( Ni et al . 2006 , Chandramohan et al . 2009 ), and inflammation ( Catania et al . 2004 , Getting et al . 2006 , Getting et al . 2008 ). The MC3R, together with MC4R

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Michael Welsh, Maria Jamalpour, Guangxiang Zang, and Björn Åkerblom

detected as selectively present in focal adhesions ( Winograd-Katz et al . 2014 ). SHB and inflammation A characteristic feature of SHB based on data obtained from the Shb knockout mouse is its involvement in inflammatory processes ( Arbiser 2015 ). An

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Ying Chen, Hua Ni, Xing-Hong Ma, Shi-Jun Hu, Li-Ming Luan, Gang Ren, Yue-Chao Zhao, Shi-Jie Li, Hong-Lu Diao, Xiu Xu, Zhen-Ao Zhao, and Zeng-Ming Yang

-implantation site on day 5 of pregnancy (Fig. 3K ), and on day 5 of pseudopregnancy (Fig. 3L ). T-cell immunoglobulin and mucin domain containing 2 ( Timd2 ) is critical for the regulation of Th2 responses during autoimmune inflammation ( Chakravarti et al. 2005

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Marc Simard, Caroline Underhill, and Geoffrey L Hammond

thought to promote the delivery of cortisol to sites of inflammation ( Hammond et al . 1990 , Lin et al . 2009 ). A metalloprotease (LasB), secreted by the pathogen Pseudomonas aeruginosa, may also contribute to the localized release of cortisol from

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Gregory S Y Ong and Morag J Young

basal cardiac MR occupancy by endogenous glucocorticoid is protective against activation. However, in situations of intracellular oxidative stress, such as with inflammation or ischaemia, glucocorticoids can activate the MR ( Rossier et al . 2008

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Shannon E Mullican, Joanna R DiSpirito, and Mitchell A Lazar ) from which this information was collated Receptor Embryonic lethal Whole body mutants Tissue-specific mutants DAX1 (NR0B1) No KO: fertility (males) NR SHP (NR0B2) No KO: fertility; energy expenditure, cholesterol metabolism, hepatic inflammation (diet

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Zhipeng Li, Zhaoshui Shangguan, Yijie Liu, Jihua Wang, Xuejun Li, Shuyu Yang, and Suhuan Liu

. 2012 ), anti-inflammation ( Huang et al . 2012 , Jin et al . 2012 ), and anti-apoptosis ( Liang et al . 2012 , Zhang et al . 2012 ) properties. It has been reported that puerarin improved insulin resistance and glucose tolerance ( Prasain et al

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Dimitrios Doultsinos and Ian Mills

involved in intestinal inflammation and promotes the development of inflammatory disorders when disrupted, as it causes imbalances in the ER homeostatic microenvironment through autophagy or secretion of AGR2 itself ( Maurel et al. 2019 ). Its little

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Ye Zhou, Eric C Bolton, and Jeremy O Jones

prostate inflammation, which causes damage that requires prostate lobe regeneration (and the increased presence of stem cells), are at a greater risk for prostate cancer ( Haverkamp et al . 2008 , Klein & Silverman 2008 , Bardia et al . 2009

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Zodwa Dlamini, Fortunate Mokoena, and Rodney Hull

). Diabetes, alternate splicing and apoptosis Type 1 diabetes is an autoimmune disease, where the immune system carries out an assault on the β-cells of the pancreas, resulting in pancreatic islet inflammation (insulitis) and β-cell apoptosis ( Santin