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Ting Qi, Yanming Chen, Honggui Li, Ya Pei, Shih-Lung Woo, Xin Guo, Jiajia Zhao, Xiaoxian Qian, Joseph Awika, Yuqing Huo, and Chaodong Wu

and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue . Cell Signal 28 1401 – 1411 . ( doi:10.1016/j.cellsig.2016.06.018 ) Zheng J Woo S-L Hu X Botchlett R

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Fumihiko Hakuno and Shin-Ichiro Takahashi

, lipolysis and protein degradation. IGFs predominantly mediate long-term action to determine the cell fates, whereas insulin mainly possesses metabolic activity. Despite the profuseness and diversity of these effects of IGFs, the in vitro biological

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Weiwei Fan, Annette R Atkins, Ruth T Yu, Michael Downes, and Ronald M Evans

Journal 27 4004 – 4016 . ( doi:10.1096/fj.13-228296 ). Maxwell MA Cleasby ME Harding A Stark A Cooney GJ Muscat GE 2005 Nur77 regulates lipolysis in skeletal muscle cells – evidence for cross-talk between the β-adrenergic and an orphan

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Zhigang Hu, Wen-Jun Shen, Fredric B Kraemer, and Salman Azhar

Kraemer FB 2001 Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway . Journal of Biological Chemistry 276 45456 – 45461 . ( doi:10.1074/jbc.M104436200 ) 10.1074/jbc.M104436200 Hiort O

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Raghunath Chatterjee, Paramita Bhattacharya, Oksana Gavrilova, Kimberly Glass, Jaideep Moitra, Max Myakishev, Stephanie Pack, William Jou, Lionel Feigenbaum, Michael Eckhaus, and Charles Vinson

thermogenic capacity of the aP2-A-C/EBP male mice, we stimulated them with the β3-adrenergic agonist, CL316243, which induces lipolysis in WAT and thermogenesis in BAT ( Himms-Hagen et al . 1994 ). In response to CL316243, the wild-type mice doubled their

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Junye Chen, Yi Lu, Mengyuan Tian, and Qiren Huang

Karki S Qiang L Tao R Kim J Luo Z Farmer SR Kandror KV 2011 SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL . Journal of Lipid Research 52 1693 – 1701 . ( https://doi.org/10.1194/jlr.M014647 ) 10.1194/jlr.M014647

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Keir Menzies and Johan Auwerx

reliant on substrates that drive OXPHOS activity. Lipids, which can be oxidized by mitochondria, are provided by lipolysis in adipose tissue and of intramuscular triacylglycerols. Carbohydrates, in the form of glucose, can be sequestered from the

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Rebecca H Ritchie, Eser J Zerenturk, Darnel Prakoso, and Anna C Calkin

al . 2008 ). Plasma TAG levels were increased by ~70% and cardiac TAG and DAG levels were both significantly elevated in diabetic mice. Interestingly, key genes involved in the regulation of lipid uptake, oxidation, FA release, lipolysis and uptake

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Shambhunath Bose, M Abul Farah, Ho-Chul Jung, Jeong-Heon Lee, and Yangsun Kim

oxidation, glycogen synthesis, and lipogenesis in addition to the inhibition of lipolysis and gluconeogenesis (reviewed by Srivastava & Mehdi 2005 ). Cumulative reports suggest that vanadium can trigger the activation of many components of insulin signaling

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Chunmei Wang and Yong Xu

Spranger J Foryst-Ludwig A Kintscher U 2012 Sexual dimorphic regulation of body weight dynamics and adipose tissue lipolysis . PLoS ONE 7 e37794 . ( https://doi.org/10.1371/journal.pone.0037794 ) Berglund ED Liu C Sohn JW Liu T Kim MH Lee CE