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J H Duncan Bassett and Graham R Williams

hormone receptors . Bone 36 607 – 616 . Liu YY Schultz JJ Brent GA 2003 A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice . Journal of

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Fumihiko Hakuno and Shin-Ichiro Takahashi

, lipolysis and protein degradation. IGFs predominantly mediate long-term action to determine the cell fates, whereas insulin mainly possesses metabolic activity. Despite the profuseness and diversity of these effects of IGFs, the in vitro biological

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Raghunath Chatterjee, Paramita Bhattacharya, Oksana Gavrilova, Kimberly Glass, Jaideep Moitra, Max Myakishev, Stephanie Pack, William Jou, Lionel Feigenbaum, Michael Eckhaus, and Charles Vinson

thermogenic capacity of the aP2-A-C/EBP male mice, we stimulated them with the β3-adrenergic agonist, CL316243, which induces lipolysis in WAT and thermogenesis in BAT ( Himms-Hagen et al . 1994 ). In response to CL316243, the wild-type mice doubled their

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Junye Chen, Yi Lu, Mengyuan Tian, and Qiren Huang

Karki S Qiang L Tao R Kim J Luo Z Farmer SR Kandror KV 2011 SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL . Journal of Lipid Research 52 1693 – 1701 . ( https://doi.org/10.1194/jlr.M014647 ) 10.1194/jlr.M014647

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Rebecca H Ritchie, Eser J Zerenturk, Darnel Prakoso, and Anna C Calkin

al . 2008 ). Plasma TAG levels were increased by ~70% and cardiac TAG and DAG levels were both significantly elevated in diabetic mice. Interestingly, key genes involved in the regulation of lipid uptake, oxidation, FA release, lipolysis and uptake

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Shambhunath Bose, M Abul Farah, Ho-Chul Jung, Jeong-Heon Lee, and Yangsun Kim

oxidation, glycogen synthesis, and lipogenesis in addition to the inhibition of lipolysis and gluconeogenesis (reviewed by Srivastava & Mehdi 2005 ). Cumulative reports suggest that vanadium can trigger the activation of many components of insulin signaling

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Chunmei Wang and Yong Xu

Spranger J Foryst-Ludwig A Kintscher U 2012 Sexual dimorphic regulation of body weight dynamics and adipose tissue lipolysis . PLoS ONE 7 e37794 . ( https://doi.org/10.1371/journal.pone.0037794 ) Berglund ED Liu C Sohn JW Liu T Kim MH Lee CE

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Cristina Velasco, Cristina Otero-Rodiño, Sara Comesaña, Jesús M Míguez, and José L Soengas

-inhibited adipocyte lipolysis . Comparative Biochemistry and Physiology A 204 76 – 84 . ( doi:10.1016/j.cbpa.2016.11.011 ) 10.1016/j.cbpa.2016.11.011 Tang Z Sun C Yan A Wu S Qin C Zhang Y Li W 2013 Genes involved in fatty acid

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Young Ho Suh, Younyoung Kim, Jeong Hyun Bang, Kyoung Suk Choi, June Woo Lee, Won-Ho Kim, Tae Jeong Oh, Sungwhan An, and Myeong Ho Jung

insulin to stimulate muscle glucose uptake and to inhibit hepatic glucose production ( Lewis et al. 2002 ). Lipolysis in adipose tissue is mediated, in part, via interaction of fatty acid binding protein (FABP) with hormone sensitive lipase ( Lewis et

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Keir Menzies and Johan Auwerx

reliant on substrates that drive OXPHOS activity. Lipids, which can be oxidized by mitochondria, are provided by lipolysis in adipose tissue and of intramuscular triacylglycerols. Carbohydrates, in the form of glucose, can be sequestered from the