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Ashley A Able, Allison J Richard, and Jacqueline M Stephens

revealed that DBC1 does not have a profound effect on the ability of GH to regulate STAT5 target genes. In studies to observe an impact of DBC1 loss in adipocytes, we found that DBC1 can impact TNFα-mediated lipolysis in mature 3T3-L1 adipocytes. Although

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Thomas Svava Nielsen, Niels Jessen, Jens Otto L Jørgensen, Niels Møller, and Sten Lund

in cytosolic lipid droplets (LDs). In conditions like fasting and exercise, when mobilization of endogenous energy stores is required, TG is hydrolyzed through the process of lipolysis and released to the circulation as free fatty acids (FFAs). These

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Heather E Bergan, Jeffrey D Kittilson, and Mark A Sheridan

Introduction Lipids play many roles in animals, but their most significant use is as an energy reserve; therefore, the breakdown of stored lipids (lipolysis) is a critical aspect of their metabolism ( Sheridan 1988 ). The main lipolytic enzyme is

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Tae Woo Jung, Hyoung-Chun Kim, Yong Kyoo Shin, Hyeyoung Min, Seong-Wan Cho, Zi Soo Kim, Su Mi Han, A M Abd El-Aty, Ahmet Hacımüftüoğlu, and Ji Hoon Jeong

in adipocytes have not yet been reported. Thus, in this study, we aimed to evaluate the effects of AH on stimulation of BAT-like phenotype in 3T3-L1 adipocytes. We further investigated the effects of AH on lipogenesis, lipolysis and oxidative stress

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Tingting Ren, Jinhan He, Hongfeng Jiang, Luxia Zu, Shenshen Pu, Xiaohui Guo, and Guoheng Xu

flux of FFA and glycerol from adipose tissue to the blood stream primarily depends on the lipolysis of triacylglycerols in adipocytes. Under physiological conditions, adipocyte lipolysis is stimulated by catecholamine hormones by elevating cellular cAMP

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C Attané, D Daviaud, C Dray, R Dusaulcy, M Masseboeuf, D Prévot, C Carpéné, I Castan-Laurell, and P Valet

triglyceride breakdown (lipolysis) into fatty acids and glycerol ( Lafontan 2008 ). Thus, we measured lipolysis and glucose uptake in AT (subcutaneous abdominal fat depot) from healthy subjects in response to increasing concentrations of apelin-13. The

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Irit Hochberg, Innocence Harvey, Quynh T Tran, Erin J Stephenson, Ariel L Barkan, Alan R Saltiel, William F Chandler, and Dave Bridges

leads to similar clinical manifestations. Numerous studies have shown that glucocorticoids have profound effects on adipose tissue metabolism, including the promotion of adipocyte differentiation ( Hauner et al . 1987 ) and induction of lipolysis and

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Tingting Zhang, Jinhan He, Chong Xu, Luxia Zu, Hongfeng Jiang, Shenshen Pu, Xiaohui Guo, and Guoheng Xu

concentration of serum FFA primarily depends on the lipolysis of adipose triacylglycerols that releases FFA and glycerol from adipocytes. Catecholamines are the most important hormones that govern lipolysis through elevating cellular cAMP production and

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Jiung-Pang Huang, Sheng-Chieh Hsu, Yaa-Jyuhn James Meir, Po-Shiuan Hsieh, Chih-Chun Chang, Kuan-Hsing Chen, Jan-Kan Chen, and Li-Man Hung

( Guilherme et al . 2008 ). Therefore, the balance between stored and released lipids is exquisitely controlled by adipose tissue. Dysfunctional adipose tissue loses the function of a metabolic homeostasis regulator and promotes lipolysis. Increased

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Yueting Dong, Zhiye Xu, Ziyi Zhang, Xueyao Yin, Xihua Lin, Hong Li, and Fenping Zheng

, whereas adipocyte number increases as a result of increased proliferation and differentiation ( Roncari et al . 1981 ). Decreases in adipose tissue mass may involve the loss of lipids through lipolysis and the loss of mature fat cells through apoptosis