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Thomas Svava Nielsen, Niels Jessen, Jens Otto L Jørgensen, Niels Møller and Sten Lund

by hormone-sensitive lipase (HSL; Haemmerle et al . 2002 ), and monoglyceride lipase (MGL) cleaves MG into glycerol and FFA ( Fredrikson et al . 1986 ). The major positive regulators of human lipolysis are catecholamines and natriuretic peptides

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Heather E Bergan, Jeffrey D Kittilson and Mark A Sheridan

hormone-sensitive lipase (HSL; Watt & Spriet 2010 ). HSL has been characterized in the adipose tissue of mammals ( Lafontan & Langin 2009 ) and in the adipose tissue and liver of fish ( Sheridan 1994 ). Interestingly, fish possess two HSL -encoding mRNAs

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M Hołysz, N Derebecka-Hołysz and W H Trzeciak

-sensitive lipase/cholesteryl esterase (HSL) EC 3.1.1.79 ( Rodrigueza et al . 1999 ). In the cytosol, free cholesterol is esterified with activated fatty acids by acyl-CoA cholesterol acyl transferase (ACAT) (EC 2.3.1.26). Cholesteryl esters formed are stored in

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Giulia Cantini, Martina Trabucco, Alessandra Di Franco, Edoardo Mannucci and Michaela Luconi

-time RT-PCR (qRT-PCR) was carried out using primers and probes for FABP4 , HSL , PPARγ and GAPDH genes (Taqman Gene Expression Assay, Life Technologies, respective codes: HS00609791_m1, Hs00193510_m1, Hs00234592_m1, FAM-MGB 4325934-1301038). The

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Hui Juan Zhu, Hui Pan, Xu Zhe Zhang, Nai Shi Li, Lin Jie Wang, Hong Bo Yang and Feng Ying Gong

accumulation, including fatty acid synthase ( Fas ), acetyl-CoA carboxylase ( Acc ), diacylglycerol O -acyltransferase ( Dgat ), and hormone-sensitive lipase ( Hsl ). Altered gene expression of these key enzymes during preadipocyte differentiation has been

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M J Watt, R J Southgate, A G Holmes and M A Febbraio

after exercise. Lipid regulatory genes FAT/CD36, HSL, CPT1 and PDK4 mRNA content were not different between trials at rest, whereas UCP3 was 3-fold greater ( P <0.05) in NA compared with CON (Table 3

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Amélie Gormand, Christine Berggreen, Lahouari Amar, Emma Henriksson, Ingrid Lund, Sebastian Albinsson and Olga Göransson

2), hormone-sensitive lipase ( Lipe /HSL) and fatty acid synthase ( Fasn /FAS) ( Cornelius et al . 1994 ). Signalling pathways that induce the adipogenic transcriptional machinery remain poorly characterised. It is generally accepted that this

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Tingting Zhang, Jinhan He, Chong Xu, Luxia Zu, Hongfeng Jiang, Shenshen Pu, Xiaohui Guo and Guoheng Xu

activating cAMP-dependent protein kinase, cAMP dependent, catalytic, alpha (PKA; Londos et al . 1999 ). PKA then phosphorylates two proteins, hormone-sensitive lipase (HSL) and perilipin, in adipocytes and causes translocation of HSL from the cytosol to the

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Jacqueline M Wallace, John S Milne, Raymond P Aitken, Dale A Redmer, Lawrence P Reynolds, Justin S Luther, Graham W Horgan and Clare L Adam

), which is involved in glyceroneogenesis, as well as lipolytic genes, such as hormone sensitive lipase ( HSL ), which is involved in the hydrolysis of stored triglycerides to release non-esterified fatty acids (NEFAs). We also measured gene expression for

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Jacqueline M Wallace, John S Milne, Raymond P Aitken and Clare L Adam

, fatty acid synthase ( FASN ), which catalyses fatty acid synthesis, and glycerol-3-phosphate dehydrogenase ( G3PDH ), which is involved in glyceroneogenesis, and lipolytic genes such as hormone-sensitive lipase ( HSL ), which is involved in the