Search Results

You are looking at 71 - 80 of 115 items for :

  • User-accessible content x
Clear All
Free access

M J Watt, R J Southgate, A G Holmes, and M A Febbraio

attenuated, suggesting that mechanisms other than FFA are important for their gene expression. Despite total suppression of lipolysis, NA ingestion at rest increased the mRNA content of PGC1α and PPARα/δ, which was associated with elevated plasma epinephrine

Free access

Penny Ahlstrom, Esther Rai, Suharto Chakma, Hee Ho Cho, Palanivel Rengasamy, and Gary Sweeney

Yan W Xia Y Chen X Wang W Zhang J Gao C Peng C Yan F 2016 Branched chain amino acids cause liver injury in obese/diabetic mice by promoting adipocyte lipolysis and inhibiting hepatic autophagy . EBioMedicine 13 157 – 167 . ( doi

Free access

Diana Vargas, Noriaki Shimokawa, Ryosuke Kaneko, Wendy Rosales, Adriana Parra, Ángela Castellanos, Noriyuki Koibuchi, and Fernando Lizcano

adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor α mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes . PNAS 98 224 – 228 . ( doi:10.1073/pnas.011528898 ). Khidr L Chen PL

Free access

R Serrano, M Villar, C Martínez, J M Carrascosa, N Gallardo, and A Andrés

lipolysis. Journal of Biological Chemistry 239 375 –385. Ruiz P , Pulido JA, Martinez C, Carrascosa JM, Satrustegui J & Andres A 1992 Effect of aging on the kinetic characteristics of the insulin receptor

Free access

Gabriela Silva Monteiro de Paula, Marianna Wilieman, Karina Ribeiro Silva, Leandra Santos Baptista, Sihem Boudina, Luana Lopes de Souza, Thais Bento-Bernardes, Karina Dutra Asensi, Regina Coeli dos Santos Goldenberg, and Carmen Cabanelas Pazos-Moura

. Regardless of the mechanism, the modulation of NB receptor activity may represent a promising target for limiting the gain weight associated with cell hyperplasia that occurs in the genesis of obesity, but not to induce loss of adiposity through lipolysis

Free access

Viral Chikani and Ken K Y Ho

availability of metabolic fuels and its capacity to synthesise ATP. The energy synthesis from substrate utilisation in exercising muscle is regulated by nutritional, genetic and hormonal factors as well as physical training. GH stimulates lipolysis during

Open access

Hyon-Seung Yi, Joon Young Chang, and Minho Shong

-sucrose diet-fed mice by sirtuin-mediated UPR mt , triggering an adaptive mitohormesis in the liver of mice ( Gariani et al . 2016 ). The UPR mt induced by skeletal muscle-specific OxPhos deficiency is also associated with enhanced lipolysis and fatty acid

Free access

Changxue Lu and Sheue-Yann Cheng

H-mutated TRα1 manifest visceral obesity, hyperleptinemia, reduced catecholamine-stimulated lipolysis in WAT, and hepatic steatosis ( Liu et al . 2007 ). In the absence of T 3 , wild-type TRα1 and P398H mutant significantly reduce PPARα

Free access

Yanxia Tang and GuoDong Li

increased plasma levels of free fatty acids (FFAs) resulting from lack of appropriate suppression of adipocyte lipolysis due to insulin resistance and deficiency ( Reaven 1988 , Imrie et al . 2010 ). Furthermore, circulating levels of FFAs are usually

Free access

L J Moran, P A Mundra, H J Teede, and P J Meikle

metabolic effects including suppression of lipogenesis and enhancement of lipolysis ( Shirouchi et al . 2007 ). Elevated lysophosphatidylcholine may indicate an increase in phospholipase activity which is highly expressed in the atherogenic plaque and