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Open access

Yali Ling, Feng Xu, Xuedi Xia, Dexing Dai, Ruoman Sun, and Zhongjian Xie

human vitamin D receptor gene associated with hypocalcemic rickets . Science 242 1702 – 1705 . ( ) 2849209 Ito Y Nikiforov YE Schlumberger M Vigneri R 2013 Increasing incidence of thyroid cancer

Open access

Ricardo Núñez Miguel, Paul Sanders, Lloyd Allen, Michele Evans, Matthew Holly, William Johnson, Andrew Sullivan, Jane Sanders, Jadwiga Furmaniak, and Bernard Rees Smith

Introduction The G-protein coupled receptor (GPCR) for thyroid-stimulating hormone (TSH) receptor (TSHR) has a key role in the regulation of thyroid function and is a major thyroid autoantigen ( Rees Smith et al. 1988 , Rapoport et al

Open access

Seema Kumar, Sarah Nadeem, Marius N Stan, Michael Coenen, and Rebecca S Bahn

Graves' hyperthyroidism, a condition in which overproduction of thyroid hormones by thyroid follicular cells is stimulated by TSH receptor (TSHR) autoantibodies (TRAb). TSHR mRNA and protein are detectable in both normal and GO orbital adipose tissues

Open access

Yoshihiro Suzuki, Keiko Nakahara, Keisuke Maruyama, Rieko Okame, Takuya Ensho, Yoshiyuki Inoue, and Noboru Murakami

.87±0.09 0.85±0.01 – Somatostatin receptor 1 0.82±0.08 0.77±0.08 – Thyroid hormone receptor β 0.89±0.04 0.90±0.07 – Tumor necrosis factor 1.06±1.06 1.01±0.21 – Thyrotropin-releasing hormone 0.94±0.94 0.89±0.04 – Thyrotropin-releasing hormone receptor 0

Open access

Stuart Baker, Ricardo Núñez Miguel, Daniel Thomas, Michael Powell, Jadwiga Furmaniak, and Bernard Rees Smith

thyroid-stimulating hormone receptor ( Rees Smith & Hall 1974 ). The TPO molecule is a glycosylated, transmembrane protein expressed predominantly on the apical surface of thyroid follicular cells facing the thyroid lumen. It is a multi-domain protein

Open access

Elizabeth M Pritchett, Susan J Lamont, and Carl J Schmidt

change in enriched genes could be in preparation for reproduction. In addition to receptors for releasing hormones from the hypothalamus, and beta subunits of follicle-stimulating hormone ( FSH ) and thyroid-stimulating hormone ( TSH ), two other genes of

Open access

Ross S Thomas, Naveed Sarwar, Fladia Phoenix, R Charles Coombes, and Simak Ali

transcriptional enhancement by the cyclin A/Cdk2 complex . PNAS 94 10132 – 10137 . Tsai MJ O'Malley BW 1994 Molecular mechanisms of action of steroid/thyroid receptor superfamily members . Annual Review of Biochemistry 63 451 – 486

Open access

Jo E Lewis, John M Brameld, Phil Hill, Dana Wilson, Perry Barrett, Francis J P Ebling, and Preeti H Jethwa

also explain why in SD there is a local upregulation of VGF expression in the dmpARC. In the hamster, this region has a much higher level of expression of thyroid hormone receptor b1 than the surrounding hypothalamus ( Barrett et al . 2007 ), and our

Open access

Emma J Agnew, Jessica R Ivy, Sarah J Stock, and Karen E Chapman

glucocorticoids act, via glucocorticoid receptor (GR), to mature the fetal lungs ( Jobe & Ikegami 2000 , Bird et al . 2015 ) and other organs, in order to survive in the extra-uterine environment after birth. Mice with global knockout of GR die shortly after

Open access

Karine Rizzoti

endocrine cells comprise lactotrophs (producing prolactin, Prl), gonadotrophs (producing luteinizing hormone, LH; and follicle stimulating hormone, FSH), thyrotrophs (producing thyroid stimulating hormone, TSH), corticotrophs (producing adrenocorticotrophic