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Open access

Rodolfo Niño Fong, Zahra Fatehi-Hassanabad, Simon C Lee, Hongfang Lu, Michael B Wheeler and Catherine B Chan

is still unclear. In pancreatic β-cells, increased UCP2 expression is associated with suppression of glucose-stimulated insulin secretion ( Chan et al . 1999 , 2001 ) and mediates the negative effects of superoxide on insulin secretion ( Krauss et

Open access

Ying Ying, Huazhang Zhu, Zhen Liang, Xiaosong Ma and Shiwei Li

Myers MG Jr Rhodes CJ 2001 Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic β-cell line INS-1 . Endocrinology 142 229 – 240 . ( doi:10.1210/endo.142

Open access

Gemma Tan, Andrew G Elefanty and Edouard G Stanley

-derived insulin-positive cells compared with adult pancreatic β cells . Diabetologia 55 358 – 371 . ( doi:10.1007/s00125-011-2335-x ). Bhushan A Itoh N Kato S Thiery JP Czernichow P Bellusci S

Open access

Daniela Nasteska and David J Hodson

-dependent periodic activation of a Ca2+-activated K+ conductance in glucose-stimulated pancreatic β-cells . Nature 353 849 – 852 . 10.1038/353849a0 Anisimova M García-Ortega LF Martínez O 2015 How many genes are expressed in a transcriptome

Open access

Tingyuan Ren, Yuping Zhu, Xuejuan Xia, Yongbo Ding, Jing Guo and Jianquan Kan

PI3K/PTEN/AKT/mTOR pathway in treatment of sarcoma cell lines . Anticancer Research 36 5765 – 5771 . ( doi:10.21873/anticanres.11160 ) Lin Y Sun Z 2015 Antiaging gene klotho attenuates pancreatic β-cell apoptosis in type 1 diabetes