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Aqfan Jamaluddin Institute of Metabolism and Systems Research (IMSR) and Centre for Diabetes, Endocrinology and Metabolism (CEDAM), University of Birmingham, Birmingham, UK
Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham, UK

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Caroline M Gorvin Institute of Metabolism and Systems Research (IMSR) and Centre for Diabetes, Endocrinology and Metabolism (CEDAM), University of Birmingham, Birmingham, UK
Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham, UK

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-coupled receptor (GPCR), calcium-sensing receptor, and its role in calcium homeostasis. Caroline moved to the IMSR in 2018 to establish her research group investigating metabolic GPCRs. Her current research focusses on how metabolic GPCRs cross-talk and interact to

Article Type:
Review Article
Collections:
Rising Stars special collection
DOI:
https://doi.org/10.1530/JME-23-0014
Volume/Issue:
Volume 70: Issue 4
Open access
Sarah Theresa Boyle Centre for Cancer Biology, SA Pathology and the University of South Australia, Adelaide, South Australia, Australia

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chemokine receptors in mammary gland biology and breast cancer, before joining the Tumour Microenvironment Laboratory at the Centre for Cancer Biology (an alliance between The University of South Australia and SA Pathology). Sarah’s research focusses on the

Article Type:
Review Article
Collections:
Rising Stars special collection
DOI:
https://doi.org/10.1530/JME-22-0174
Volume/Issue:
Volume 70: Issue 3
Free access
Hiroshi Ishikawa Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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Tatsuya Kobayashi Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan
Evolution and Reproductive Medicine, Medical Mycology Research Center, Chiba University, Chiba, Japan
Fujita Medical Innovation Center Tokyo, Reproduction Center, Tokyo, Japan

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Meika Kaneko Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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Yoshiko Saito Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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Makio Shozu Evolution and Reproductive Medicine, Medical Mycology Research Center, Chiba University, Chiba, Japan

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Kaori Koga Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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for UFs. MED12-UFs became smaller in response to ulipristal acetate, a selective progesterone receptor (PR) modulator that shrinks UFs, as compared to HMGA2 overexpressing UFs. ChIP-seq revealed that PR-binding sites were less methylated in MED12-UFs

Article Type:
Review Article
Collections:
Rising Stars special collection
DOI:
https://doi.org/10.1530/JME-23-0039
Volume/Issue:
Volume 71: Issue 4
Free access
Dorka Nagy Department of Metabolism, Digestion and Reproduction, Section of Genetics and Genomics, Imperial College London, London, UK
National Heart and Lung Institute, Imperial College London, London, UK

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Hannah Maude Department of Metabolism, Digestion and Reproduction, Section of Genetics and Genomics, Imperial College London, London, UK

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Graeme M Birdsey National Heart and Lung Institute, Imperial College London, London, UK

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Anna M Randi National Heart and Lung Institute, Imperial College London, London, UK

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Inês Cebola Department of Metabolism, Digestion and Reproduction, Section of Genetics and Genomics, Imperial College London, London, UK

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, canonical Wnt signalling, as well as the binding and uptake of ligands by scavenger receptors ( Paris & Henderson 2022 ). Notably, pericentral LSECs secrete Wnt morphogens, which play an important role in zonation ( Preziosi et al. 2018 ). Zonation may be

Article Type:
Review Article
Collections:
Rising Stars special collection
DOI:
https://doi.org/10.1530/JME-23-0026
Volume/Issue:
Volume 71: Issue 2
Open access