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Sarah Theresa Boyle Centre for Cancer Biology, SA Pathology and the University of South Australia, Adelaide, South Australia, Australia

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Invited Author’s profile Sarah Boyle is an Australian Research Council DECRA Research Fellow at the Centre for Cancer Biology in Adelaide, South Australia. Sarah completed her PhD at the University of Adelaide, investigating the roles of

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Hiroshi Ishikawa Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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Tatsuya Kobayashi Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan
Evolution and Reproductive Medicine, Medical Mycology Research Center, Chiba University, Chiba, Japan
Fujita Medical Innovation Center Tokyo, Reproduction Center, Tokyo, Japan

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Meika Kaneko Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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Yoshiko Saito Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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Makio Shozu Evolution and Reproductive Medicine, Medical Mycology Research Center, Chiba University, Chiba, Japan

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Kaori Koga Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan

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Hereditary leiomyomatosis and renal cell cancer COL4A5/COL4A6 Collagen type 4 alpha 5 chain/collagen type 4 alpha 6 chain Deletions Less than 1% Unknown Alport syndrome Driver gene mutations in UFs MED12 mutations are

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Dorka Nagy Department of Metabolism, Digestion and Reproduction, Section of Genetics and Genomics, Imperial College London, London, UK
National Heart and Lung Institute, Imperial College London, London, UK

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Hannah Maude Department of Metabolism, Digestion and Reproduction, Section of Genetics and Genomics, Imperial College London, London, UK

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Graeme M Birdsey National Heart and Lung Institute, Imperial College London, London, UK

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Anna M Randi National Heart and Lung Institute, Imperial College London, London, UK

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Inês Cebola Department of Metabolism, Digestion and Reproduction, Section of Genetics and Genomics, Imperial College London, London, UK

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and in epithelial-to-mesenchymal transition in cancer ( Fardi et al. 2019 ). ZEB2 was recently shown to be enriched in liver microvascular ECs ( de Haan et al. 2020 ). However, experimental follow-up for the role of ZEB2 in LSECs showed uniform

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Aqfan Jamaluddin Institute of Metabolism and Systems Research (IMSR) and Centre for Diabetes, Endocrinology and Metabolism (CEDAM), University of Birmingham, Birmingham, UK
Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham, UK

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Caroline M Gorvin Institute of Metabolism and Systems Research (IMSR) and Centre for Diabetes, Endocrinology and Metabolism (CEDAM), University of Birmingham, Birmingham, UK
Centre of Membrane Proteins and Receptors (COMPARE), Universities of Birmingham and Nottingham, Birmingham, UK

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feeding, which led to the development of the selective 5-HT 2C R agonist lorcaserin. Although lorcaserin was clinically approved to improve weight loss, it was withdrawn in 2020 due to a possible increased occurrence of cancer. An improved understanding of

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