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Tae Woo Jung Research Administration Team, Seoul National University Bundang Hospital, Gyeonggi, Republic of Korea

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Yoon Hee Chung Department of Anatomy, College of Medicine, Chung-Ang University, Seoul, Republic of Korea

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Hyoung-Chun Kim Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea

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A M Abd El-Aty Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
Department of Medical Pharmacology, Medical Faculty, Ataturk University, Erzurum, Turkey

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Ji Hoon Jeong Department of Pharmacology, College of Medicine, Chung-Ang University, Seoul, Republic of Korea

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inflammation and insulin resistance in differentiated 3T3-L1 cells and (2) the mechanisms of LECT2-mediated stimulation of inflammation and insulin resistance through CD209/P38/NF-κB-dependent signaling. Materials and methods Cell culture, reagents

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-17-0267
Volume/Issue:
Volume 61: Issue 1
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Lingxia Pang Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China
Institute of Pediatrics, Nanjing Medical University, Nanjing, China

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Lianghui You Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China

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Chenbo Ji Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China

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Chunmei Shi Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China

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Ling Chen Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China

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Lei Yang Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China
Institute of Pediatrics, Nanjing Medical University, Nanjing, China

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Fangyan Huang Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China
Institute of Pediatrics, Nanjing Medical University, Nanjing, China

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Yahui Zhou Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China
Institute of Pediatrics, Nanjing Medical University, Nanjing, China

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Jun Zhang Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China

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Xiaohui Chen Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China

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Xirong Guo Department of Children Health Care, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing, China
Institute of Pediatrics, Nanjing Medical University, Nanjing, China

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differentiation ( Yeh et al . 1995 , ­ Lefterova et al . 2008 ). Many other transcriptional ­cofactors serve as molecular scaffolds to link the basal transcription machinery with either active or inactive complexes; examples include early adipogenic factors such

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-16-0007
Volume/Issue:
Volume 57: Issue 1
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Laure Quignodon Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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Carmen Grijota-Martinez Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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Emmanuel Compe Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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Romain Guyot Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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Nathalie Allioli Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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David Laperrière Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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Robert Walker Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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Paul Meltzer Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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Sylvie Mader Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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Jacques Samarut Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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Frédéric Flamant Institut de Génomique Fonctionnelle de Lyon, Ecole Normale Supérieure de Lyon, Université de Lyon, UMR INRA CNRS 5242, IFR128 46 allée d’Italie, 69364 Lyon Cedex 07, France
Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) and Center for Biomedical Research on Rare Diseases (CIBERER), 28029 Madrid, Spain
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France
Cancer Genetics Branch, NHGRI, Bethesda, Maryland, USA
Institut de recherche en Immunologie et Cancer, Université de Montréal, Montréal H3C3J7, Quebec, Canada

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birth. The EGL cells are capable of self-renewal or migration toward the inner granular layer, where they undergo terminal differentiation. Hypothyroidism results in delayed proliferation, reduced migration, and increased rate of apoptosis of EGL cells

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-06-0054
Volume/Issue:
Volume 39: Issue 1
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Amanda M Ackermann Departments of Medicine,
Molecular Physiology and Biophysics and
Program in Developmental Biology, Vanderbilt University Medical Center, 2220 Pierce Avenue 746 PRB, Nashville, Tennessee 37232, USA

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Maureen Gannon Departments of Medicine,
Molecular Physiology and Biophysics and
Program in Developmental Biology, Vanderbilt University Medical Center, 2220 Pierce Avenue 746 PRB, Nashville, Tennessee 37232, USA

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, efforts are being made to differentiate β-cells from precursor populations and to expand β-cells in vitro to generate an unlimited supply of β-cells for transplantation. Theoretically, the same could be done in vivo to expand a patient’s existing or

Article Type:
Review Article
DOI:
https://doi.org/10.1677/JME-06-0053
Volume/Issue:
Volume 38: Issue 2
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Mitsushige Ando Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

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Masanori Goto Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

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Masato Hojo Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
Department of Neurosurgery, Shiga Medical Center for Adults, Shiga, Japan

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Aya Kita Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

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Masashi Kitagawa Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

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Toshiyuki Ohtsuka Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

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Ryoichiro Kageyama Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan

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Susumu Miyamoto Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

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). Pit1 is required for terminal differentiation of endocrine cells such as thyrotropes, somatotropes and lactotropes ( Lin et al . 1994 ). Differentiation of corticotropes is dependent on Tpit / Tbx19 ( Liu et al . 2001 , Lamolet et al . 2004

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-18-0090
Volume/Issue:
Volume 61: Issue 3
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Denise Vizziano-Cantonnet Facultad de Ciencias, INRA, Oceanología, Iguá 4225, Montevideo 11400, Uruguay
Facultad de Ciencias, INRA, Oceanología, Iguá 4225, Montevideo 11400, Uruguay

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Daniel Baron Facultad de Ciencias, INRA, Oceanología, Iguá 4225, Montevideo 11400, Uruguay

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Sophie Mahè Facultad de Ciencias, INRA, Oceanología, Iguá 4225, Montevideo 11400, Uruguay

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Chantal Cauty Facultad de Ciencias, INRA, Oceanología, Iguá 4225, Montevideo 11400, Uruguay

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Alexis Fostier Facultad de Ciencias, INRA, Oceanología, Iguá 4225, Montevideo 11400, Uruguay

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Yann Guiguen Facultad de Ciencias, INRA, Oceanología, Iguá 4225, Montevideo 11400, Uruguay

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receptivity has been shown to affect ovarian differentiation in most vertebrate species. In contrast to the important effects of estrogens on ovarian differentiation in non-mammalian vertebrates, the gonads in eutherian mammals appear quite insensitive to

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-08-0039
Volume/Issue:
Volume 41: Issue 5
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Jin-Seung Choung College of Pharmacy and Gachon Institute of Pharmaceutical Science, Gachon University, Incheon, Republic of Korea
Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea

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Young-Sun Lee Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea

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Hee-Sook Jun College of Pharmacy and Gachon Institute of Pharmaceutical Science, Gachon University, Incheon, Republic of Korea
Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea
Gachon Medical Research Institute, Gil Hospital, Incheon, Republic of Korea

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/mL streptomycin at 37°C in a humidified atmosphere containing 95% (v/v) air and 5% (v/v) CO 2 . The cells were seeded at a density of 5.0 × 10 5 /well in 6-well plates. To induce the myogenic differentiation of C2C12 cells, the cells were cultured to 85% (v

Article Type:
Research Article
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https://doi.org/10.1530/JME-16-0078
Volume/Issue:
Volume 58: Issue 2
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K Raghuveer Department of Animal Sciences, School of Life Sciences, University of Hyderabad, PO Central University, Gachibowli, Hyderabad 500 046, Andhra Pradesh, India

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B Senthilkumaran Department of Animal Sciences, School of Life Sciences, University of Hyderabad, PO Central University, Gachibowli, Hyderabad 500 046, Andhra Pradesh, India

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Introduction Several transcription factors like sry , dmy , sox9 , ad4BP/SF-1 , dmrt1 , dax1 and wt1 have been identified to play an important role in sex determination and differentiation of vertebrates including teleosts ( Swain & Lovell

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-09-0011
Volume/Issue:
Volume 42: Issue 5
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Ana P Irazoqui INBIOSUR – CONICET, Departamento de Biología, Bioquímica and Farmacia, Universidad Nacional del Sur, San Juan 670, 8000 Bahía Blanca, Argentina

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Ricardo L Boland INBIOSUR – CONICET, Departamento de Biología, Bioquímica and Farmacia, Universidad Nacional del Sur, San Juan 670, 8000 Bahía Blanca, Argentina

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Claudia G Buitrago INBIOSUR – CONICET, Departamento de Biología, Bioquímica and Farmacia, Universidad Nacional del Sur, San Juan 670, 8000 Bahía Blanca, Argentina

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Introduction Recruitment of cells in G0/G1 stage is a pre- and pro-differentiation arrest of skeletal muscle myoblasts, necessary to the subsequent development of myotubes ( Mercer et al . 2005 ). For cell cycle progression, the cellular exit from

Article Type:
Research Article
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https://doi.org/10.1530/JME-14-0102
Volume/Issue:
Volume 53: Issue 3
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Maurizio Longo
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Barbara Peruzzi
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Dario Fortunati
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Veronica De Luca
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Stefanie Denger
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Gianfranco Caselli
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Silvia Migliaccio
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Anna Teti
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in ERα F-promoter modulation has been studied in proliferating and resting osteoblast-like cells, in the light of the well-known involvement of these kinases in osteoblast differentiation ( Migliaccio et al. 1993 , Davis et al. 1994 ) and their

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.02055
Volume/Issue:
Volume 37: Issue 3
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