Search Results

You are looking at 61 - 70 of 1,100 items for :

  • "differentiation" x
  • Refine by access: All content x
Clear All
E Anastasi Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by E Anastasi in
Google Scholar
PubMed
Close
,
C Santangelo Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by C Santangelo in
Google Scholar
PubMed
Close
,
A Bulotta Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by A Bulotta in
Google Scholar
PubMed
Close
,
F Dotta Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by F Dotta in
Google Scholar
PubMed
Close
,
B Argenti Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by B Argenti in
Google Scholar
PubMed
Close
,
C Mincione Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by C Mincione in
Google Scholar
PubMed
Close
,
A Gulino Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by A Gulino in
Google Scholar
PubMed
Close
,
M Maroder Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by M Maroder in
Google Scholar
PubMed
Close
,
R Perfetti Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by R Perfetti in
Google Scholar
PubMed
Close
, and
U Di Mario Department of Clinical Sciences, University ‘La Sapienza’, Rome, Italy
National Centre for Food Quality and Risk Assessment, Section of Nutrition, Istituto Superiore di Sanità, Rome, Italy
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, University of California, Los Angeles, CA, USA
Department of Experimental Medicine and Pathology, University ‘La Sapienza’, Rome, Italy

Search for other papers by U Di Mario in
Google Scholar
PubMed
Close

). The process of islet cell regeneration leads, after an initial phase of cell replication, to the acquisition of a number of phenotypic features that are characteristic of differentiated insulin-producing cells ( Hardikar 2004 ). However, whether such a

Free access
Jonathan Pham Department of Pathology, University of California San Diego, La Jolla, California, USA
Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA

Search for other papers by Jonathan Pham in
Google Scholar
PubMed
Close
,
Kanaga Arul Nambi Rajan Department of Pathology, University of California San Diego, La Jolla, California, USA
Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA

Search for other papers by Kanaga Arul Nambi Rajan in
Google Scholar
PubMed
Close
,
Ping Li Department of Pathology, Medical School of Jinan University, Guangzhou, China

Search for other papers by Ping Li in
Google Scholar
PubMed
Close
, and
Mana M Parast Department of Pathology, University of California San Diego, La Jolla, California, USA
Sanford Consortium for Regenerative Medicine, University of California San Diego, La Jolla, California, USA

Search for other papers by Mana M Parast in
Google Scholar
PubMed
Close

to the mesenchymal portions of the placenta, including the fetal vasculature, the TE differentiates into two major trophoblast subtypes: villous trophoblast (labyrinthine trophoblast in mouse), involved in gas and nutrient exchange, and extravillous

Free access
Gabriela Silva Monteiro de Paula Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Gabriela Silva Monteiro de Paula in
Google Scholar
PubMed
Close
,
Marianna Wilieman Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Marianna Wilieman in
Google Scholar
PubMed
Close
,
Karina Ribeiro Silva Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Post-Graduation Program of Biotechnology, National Institute of Metrology, Quality and Technology – INMETRO, Rio de Janeiro, Brazil
Multidisciplinary Center for Biological Research (Numpex-Bio), Federal University of Rio de Janeiro – Campus of Duque de Caxias, Rio de Janeiro, Brazil

Search for other papers by Karina Ribeiro Silva in
Google Scholar
PubMed
Close
,
Leandra Santos Baptista Post-Graduation Program of Biotechnology, National Institute of Metrology, Quality and Technology – INMETRO, Rio de Janeiro, Brazil
Multidisciplinary Center for Biological Research (Numpex-Bio), Federal University of Rio de Janeiro – Campus of Duque de Caxias, Rio de Janeiro, Brazil

Search for other papers by Leandra Santos Baptista in
Google Scholar
PubMed
Close
,
Sihem Boudina Department of Nutrition and Integrative Physiology, University of Utah School of Medicine, Salt Lake City, Utah, USA

Search for other papers by Sihem Boudina in
Google Scholar
PubMed
Close
,
Luana Lopes de Souza Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Luana Lopes de Souza in
Google Scholar
PubMed
Close
,
Thais Bento-Bernardes Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Thais Bento-Bernardes in
Google Scholar
PubMed
Close
,
Karina Dutra Asensi Cellular and Molecular Cardiology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
National Center of Structural Biology and Bioimage – CENABIO, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Karina Dutra Asensi in
Google Scholar
PubMed
Close
,
Regina Coeli dos Santos Goldenberg Cellular and Molecular Cardiology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Regina Coeli dos Santos Goldenberg in
Google Scholar
PubMed
Close
, and
Carmen Cabanelas Pazos-Moura Molecular Endocrinology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Carmen Cabanelas Pazos-Moura in
Google Scholar
PubMed
Close

perigonadal region of female NB-RKO mice to differentiate under adipogenic stimuli in vitro . In addition, to further explore mechanisms, we tested the effect of blocking the NB-R, employing a pharmacology antagonist, on the ability of the committed

Free access
N Salma Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA

Search for other papers by N Salma in
Google Scholar
PubMed
Close
,
H Xiao Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA

Search for other papers by H Xiao in
Google Scholar
PubMed
Close
, and
A N Imbalzano Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA

Search for other papers by A N Imbalzano in
Google Scholar
PubMed
Close

Introduction The major transcription factor families involved as key regulators of adipocyte differentiation include the nuclear hormone receptor peroxisome proliferator activated receptor (PPAR) γ and the CCAAT

Free access
Chen Chen Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry and Key Laboratory of Agricultural Animal Genetics, Hunan Institute of Animal and Veterinary Science, Department of Animal Nutrition and Feed Science, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, People's Republic of China
Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry and Key Laboratory of Agricultural Animal Genetics, Hunan Institute of Animal and Veterinary Science, Department of Animal Nutrition and Feed Science, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, People's Republic of China

Search for other papers by Chen Chen in
Google Scholar
PubMed
Close
,
Yongdong Peng Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry and Key Laboratory of Agricultural Animal Genetics, Hunan Institute of Animal and Veterinary Science, Department of Animal Nutrition and Feed Science, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, People's Republic of China

Search for other papers by Yongdong Peng in
Google Scholar
PubMed
Close
,
Yinglin Peng Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry and Key Laboratory of Agricultural Animal Genetics, Hunan Institute of Animal and Veterinary Science, Department of Animal Nutrition and Feed Science, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, People's Republic of China

Search for other papers by Yinglin Peng in
Google Scholar
PubMed
Close
,
Jian Peng Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry and Key Laboratory of Agricultural Animal Genetics, Hunan Institute of Animal and Veterinary Science, Department of Animal Nutrition and Feed Science, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, People's Republic of China

Search for other papers by Jian Peng in
Google Scholar
PubMed
Close
, and
Siwen Jiang Key Laboratory of Swine Genetics and Breeding of Agricultural Ministry and Key Laboratory of Agricultural Animal Genetics, Hunan Institute of Animal and Veterinary Science, Department of Animal Nutrition and Feed Science, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, People's Republic of China

Search for other papers by Siwen Jiang in
Google Scholar
PubMed
Close

lineage and terminal differentiation, and finally differentiate into mature adipocytes ( Lefterova & Lazar 2009 ). Adipose tissue development is a complex process involving a cascade of multiple adipogenic transcription factors C/EBPβ, C/EBPδ, ADD1/SREBP1c

Free access
Beatriz Gámez Departament de Ciències Fisiològiques II, Universitat de Barcelona, IDIBELL, C/Feixa Llarga s/n, E-08907 L'Hospitalet de Llobregat, Spain

Search for other papers by Beatriz Gámez in
Google Scholar
PubMed
Close
,
Edgardo Rodriguez-Carballo Departament de Ciències Fisiològiques II, Universitat de Barcelona, IDIBELL, C/Feixa Llarga s/n, E-08907 L'Hospitalet de Llobregat, Spain

Search for other papers by Edgardo Rodriguez-Carballo in
Google Scholar
PubMed
Close
, and
Francesc Ventura Departament de Ciències Fisiològiques II, Universitat de Barcelona, IDIBELL, C/Feixa Llarga s/n, E-08907 L'Hospitalet de Llobregat, Spain

Search for other papers by Francesc Ventura in
Google Scholar
PubMed
Close

crosstalk between them: osteoblasts are involved in the regulation of osteoclast differentiation through the receptor activator of nuclear factor κB ligand (RANKL)–RANK pathway, essential for a satisfactory balance between bone deposition and bone resorption

Free access
J J Brosens Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London W12 ONN, United Kingdom
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

Search for other papers by J J Brosens in
Google Scholar
PubMed
Close
and
B Gellersen Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London W12 ONN, United Kingdom
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

Search for other papers by B Gellersen in
Google Scholar
PubMed
Close

postovulatory rise in progesterone levels controls differentiation of this tissue in preparation for an implanting embryo. In the absence of pregnancy, ovarian hormone levels fall and the endometrial epithelial cells regress. At least this is the scenario in

Free access
Amélie Gormand
Search for other papers by Amélie Gormand in
Google Scholar
PubMed
Close
,
Christine Berggreen
Search for other papers by Christine Berggreen in
Google Scholar
PubMed
Close
,
Lahouari Amar
Search for other papers by Lahouari Amar in
Google Scholar
PubMed
Close
,
Emma Henriksson
Search for other papers by Emma Henriksson in
Google Scholar
PubMed
Close
,
Ingrid Lund Department of Experimental Medical Science, Department of Biomedicine, Lund University, BMC C11, 221 84 Lund, Sweden

Search for other papers by Ingrid Lund in
Google Scholar
PubMed
Close
,
Sebastian Albinsson
Search for other papers by Sebastian Albinsson in
Google Scholar
PubMed
Close
, and
Olga Göransson
Search for other papers by Olga Göransson in
Google Scholar
PubMed
Close

Introduction Adipogenesis is a multistep process through which progenitor cells differentiate into functional adipocytes and involves a cascade of adipogenic transcription factors and genes that define the adipocyte phenotype ( Rosen 2005 ). In

Free access
Cristina L Esteves
Search for other papers by Cristina L Esteves in
Google Scholar
PubMed
Close
,
Val Kelly
Search for other papers by Val Kelly in
Google Scholar
PubMed
Close
,
Valérie Bégay Endocrinology Unit, Max Delbrüeck Centre for Molecular Medicine, Division of Developmental Biology, Queen's Medical Research Institute, University/BHF Centre for Cardiovascular Science, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

Search for other papers by Valérie Bégay in
Google Scholar
PubMed
Close
,
Simon G Lillico Endocrinology Unit, Max Delbrüeck Centre for Molecular Medicine, Division of Developmental Biology, Queen's Medical Research Institute, University/BHF Centre for Cardiovascular Science, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

Search for other papers by Simon G Lillico in
Google Scholar
PubMed
Close
,
Achim Leutz Endocrinology Unit, Max Delbrüeck Centre for Molecular Medicine, Division of Developmental Biology, Queen's Medical Research Institute, University/BHF Centre for Cardiovascular Science, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

Search for other papers by Achim Leutz in
Google Scholar
PubMed
Close
,
Jonathan R Seckl
Search for other papers by Jonathan R Seckl in
Google Scholar
PubMed
Close
, and
Karen E Chapman
Search for other papers by Karen E Chapman in
Google Scholar
PubMed
Close

obesity-related disorders. However, introduction of nucleic acids and, consequently, the manipulation of genes in fully differentiated 3T3-L1 adipocytes are difficult to achieve. pSLIK plasmids, encoding a tetracycline-regulated transcriptional unit in a

Open access
Hui Juan Zhu Key Laboratory of Endocrinology of Ministry of Health, Department of Endocrinology, The Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Wangfujing, Beijing 100730, China

Search for other papers by Hui Juan Zhu in
Google Scholar
PubMed
Close
,
Hui Pan Key Laboratory of Endocrinology of Ministry of Health, Department of Endocrinology, The Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Wangfujing, Beijing 100730, China

Search for other papers by Hui Pan in
Google Scholar
PubMed
Close
,
Xu Zhe Zhang Key Laboratory of Endocrinology of Ministry of Health, Department of Endocrinology, The Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Wangfujing, Beijing 100730, China

Search for other papers by Xu Zhe Zhang in
Google Scholar
PubMed
Close
,
Nai Shi Li Key Laboratory of Endocrinology of Ministry of Health, Department of Endocrinology, The Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Wangfujing, Beijing 100730, China

Search for other papers by Nai Shi Li in
Google Scholar
PubMed
Close
,
Lin Jie Wang Key Laboratory of Endocrinology of Ministry of Health, Department of Endocrinology, The Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Wangfujing, Beijing 100730, China

Search for other papers by Lin Jie Wang in
Google Scholar
PubMed
Close
,
Hong Bo Yang Key Laboratory of Endocrinology of Ministry of Health, Department of Endocrinology, The Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Wangfujing, Beijing 100730, China

Search for other papers by Hong Bo Yang in
Google Scholar
PubMed
Close
, and
Feng Ying Gong Key Laboratory of Endocrinology of Ministry of Health, Department of Endocrinology, The Translational Medicine Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Wangfujing, Beijing 100730, China

Search for other papers by Feng Ying Gong in
Google Scholar
PubMed
Close

particular, the balance between cell acquisition and cell loss ( Fruhbeck 2008 ). The proliferation of preadipocytes and their differentiation into mature adipocytes, combined with the apoptosis of preadipocytes, all contribute to the development of obesity

Free access