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Henrik Fagman Department of Pathology, Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy at the University of Gothenburg, Gula Stråket 8, 413 45 Göteborg, Sweden

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Mikael Nilsson Department of Pathology, Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy at the University of Gothenburg, Gula Stråket 8, 413 45 Göteborg, Sweden

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gut tube closes and glandular derivatives of the endoderm and the heart and central vessels develop in a coordinated manner. In this process, mesoderm regions that generate inductive signals such as fibroblast growth factors (FGFs), WNT, retinoic acid

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-10-0084
Volume/Issue:
Volume 46: Issue 1
Free access
Rosalia C M Simmen
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Melissa E Heard
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Angela M Simmen Department of Physiology and Biophysics, Department of Obstetrics and Gynecology, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA

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Maria Theresa M Montales
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Meera Marji
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Samantha Scanlon
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John Mark P Pabona Department of Physiology and Biophysics, Department of Obstetrics and Gynecology, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA

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with KLF9 loss-of-expression were partly attributed to disruptions in the temporal patterns of expression of the Wnt signaling pathway components BMP2 , PGR (specifically the PGR-B isoform), and insulin-like growth factor-binding protein 1 ( IGFBP1

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-14-0310
Volume/Issue:
Volume 54: Issue 2
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Fabio Luiz Fernandes-Rosa INSERM, UMRS_970, Paris Cardiovascular Research Center, Paris, France
University Paris Descartes, Sorbonne Paris Cité, Paris, France
Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Génétique, Paris, France

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Sheerazed Boulkroun INSERM, UMRS_970, Paris Cardiovascular Research Center, Paris, France
University Paris Descartes, Sorbonne Paris Cité, Paris, France

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Maria-Christina Zennaro INSERM, UMRS_970, Paris Cardiovascular Research Center, Paris, France
University Paris Descartes, Sorbonne Paris Cité, Paris, France
Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Génétique, Paris, France

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al . 2014 ). Mutations affecting β-catenin activation Activation of Wnt/β-catenin pathway is one of the major features in APA, being found in at least two-thirds of APA ( Boulkroun et al . 2011 , Berthon et al . 2012 , Berthon & Stratakis

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-17-0035
Volume/Issue:
Volume 59: Issue 1
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Murat Bastepe Endocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA

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Serap Turan Department of Pediatric Endocrinology, Marmara University School of Medicine, Istanbul, Turkey

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Qing He Endocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA

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this protein in osteoblasts (using osteocalcin–Cre) markedly impairs the osteoanabolic activity of PTH ( Thouverey & Caverzasio 2016 ). PTH signaling also cross-talks with the Wnt/β-catenin signaling to promote osteogenesis. Wnt/β-catenin signaling

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-16-0221
Volume/Issue:
Volume 58: Issue 4
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Yasmine Hachemi Institute of Comparative Molecular Endocrinology, Ulm University, Ulm, Germany

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Anna E Rapp Institute of Orthopaedic Research and Biomechanics, Ulm University Medical Centre, Ulm, Germany

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Ann-Kristin Picke Institute of Comparative Molecular Endocrinology, Ulm University, Ulm, Germany

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Gilbert Weidinger Institute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany

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Anita Ignatius Institute of Orthopaedic Research and Biomechanics, Ulm University Medical Centre, Ulm, Germany

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Jan Tuckermann Institute of Comparative Molecular Endocrinology, Ulm University, Ulm, Germany

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(OCN), and Wnt ligands (7b, 10b) and a simultaneous increase in expression of Wnt signalling inhibitors, including sclerostin (SCL), dickkopf-1 (DKK1), and Wnt-inhibitory factor (WIF1), as well as the adipogenic markers peroxisome proliferator

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-18-0024
Volume/Issue:
Volume 61: Issue 1
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Excel Rio S Maylem Department of Animal and Food Sciences, Oklahoma State University, Stillwater, Oklahoma, USA

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Leon J Spicer Department of Animal and Food Sciences, Oklahoma State University, Stillwater, Oklahoma, USA

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Isadora Batalha Department of Agriculture, Veterinary, and Rangeland Sciences, University of Nevada, Reno, Nevada, USA

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Luis F Schutz Department of Agriculture, Veterinary, and Rangeland Sciences, University of Nevada, Reno, Nevada, USA

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wingless-type MMTV integration site family member 3A (WNT3A) from R&D Systems (Minneapolis, MN); testosterone from Steraloids (Wilton, NH); recombinant human asprosin from Biologics Inc. (Cary, NC); and fetal calf serum (FCS) from Atlanta Biologicals

Article Type:
Research Article
Collections:
Top-cited articles of 2023
DOI:
https://doi.org/10.1530/JME-20-0218
Volume/Issue:
Volume 66: Issue 1
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Yangli Xie Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, Trauma Center, State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China

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Siru Zhou Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, Trauma Center, State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China

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Hangang Chen Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, Trauma Center, State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China

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Xiaolan Du Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, Trauma Center, State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China

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Lin Chen Department of Rehabilitation Medicine, Center of Bone Metabolism and Repair, Trauma Center, State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China

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tightly regulated by various systemic and local molecules such as growth hormone, thyroid hormone, bone morphogenetic proteins (BMPs), Wnt/β-catenin, FGFs, and transforming and growth factor (TGF) β ( Long & Ornitz 2013 ). Previous work revealed that

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-14-0012
Volume/Issue:
Volume 53: Issue 1
Free access
Yingying Zhu Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, China

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Weiwei Liu Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, China

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Shuaigao Chen Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, China

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Fanxing Xu Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, China

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Luxin Zhang Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, China

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Toshihiko Hayashi Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, China
Department of Chemistry and Life Science, School of Advanced Engineering Kogakuin University, Tokyo, Japan
Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan

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Kazunori Mizuno Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan

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Shunji Hattori Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan

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Hitomi Fujisaki Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan

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Takashi Ikejima Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning, China
Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research and Development, Liaoning, China

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– 1059 . ( https://doi.org/10.1016/j.cell.2013.07.042 ) Baarsma HA Spanjer AI Haitsma G Engelbertink LH Meurs H Jonker MR Timens W Postma DS Kerstjens HA Gosens R 2011 Activation of WNT/beta-catenin signaling in pulmonary

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-21-0032
Volume/Issue:
Volume 67: Issue 3
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M H Abel
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D Baban
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S Lee
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H M Charlton
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P J O'Shaughnessy Department of Physiology, Institute of Comparative Medicine, Anatomy and Genetics, University of Oxford, Le Gros Clarke Building, Oxford OX1 3QX, UK

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interactor 2 13.3 Aqp5 Aquaporin 5 5.03 Pdgfc Platelet-derived growth factor C 12.1 Wif1 Wnt inhibitory factor 1 4.55 Transcribed locus b 11.0 Fabp5 Fatty acid binding protein 5, epidermal 4.53 Bcan Brevican 6.6 Tubb3 Tubulin, β 3 4.46 Rgs11 Regulator of G

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-08-0107
Volume/Issue:
Volume 42: Issue 4
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Elizabeth M Pritchett Animal and Food Science, University of Delaware, Newark, Delaware, USA

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Susan J Lamont Animal Science, Iowa State University, Ames, Iowa, USA

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Carl J Schmidt Animal and Food Science, University of Delaware, Newark, Delaware, USA

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transduction ADORA1, ARHGEF4, CHRDL1, CNTN1, COL9A3, EGF, ERBB4, FZD10, GFAP, GNAO1, GPR17, GREM2, GRM3, GRM7, GRPR, HRH3, NPBWR1, NRG3, NTRK2, PDE4A, PDE8B, RAMP1, WNT11, WNT6, WNT7B Neuronal system CACNG4, CHRNA4, GABRA3, GRIA4, GRIK2, GRIK3, KCNK2

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-16-0186
Volume/Issue:
Volume 58: Issue 1
Open access