Filter

Refine by collections

Refine by access

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 31 - 40 of 1,550 items for :

  • transcription x
  • Refine by access: All content x
Clear All
Anne Wulf Zentrum für Experimentelle Medizin, Institut für Experimentelle Endokrinologie, Department of Reproductive Biology, Institut für Biochemie und Molekularbiologie I, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany

Search for other papers by Anne Wulf in
Google Scholar
PubMed Close
,
Marianne G Wetzel Zentrum für Experimentelle Medizin, Institut für Experimentelle Endokrinologie, Department of Reproductive Biology, Institut für Biochemie und Molekularbiologie I, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany

Search for other papers by Marianne G Wetzel in
Google Scholar
PubMed Close
,
Maxim Kebenko Zentrum für Experimentelle Medizin, Institut für Experimentelle Endokrinologie, Department of Reproductive Biology, Institut für Biochemie und Molekularbiologie I, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany

Search for other papers by Maxim Kebenko in
Google Scholar
PubMed Close
,
Meike Kröger Zentrum für Experimentelle Medizin, Institut für Experimentelle Endokrinologie, Department of Reproductive Biology, Institut für Biochemie und Molekularbiologie I, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany

Search for other papers by Meike Kröger in
Google Scholar
PubMed Close
,
Angelika Harneit Zentrum für Experimentelle Medizin, Institut für Experimentelle Endokrinologie, Department of Reproductive Biology, Institut für Biochemie und Molekularbiologie I, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany

Search for other papers by Angelika Harneit in
Google Scholar
PubMed Close
,
Jennifer Merz Zentrum für Experimentelle Medizin, Institut für Experimentelle Endokrinologie, Department of Reproductive Biology, Institut für Biochemie und Molekularbiologie I, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany

Search for other papers by Jennifer Merz in
Google Scholar
PubMed Close
, and
Joachim M Weitzel Zentrum für Experimentelle Medizin, Institut für Experimentelle Endokrinologie, Department of Reproductive Biology, Institut für Biochemie und Molekularbiologie I, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany
Zentrum für Experimentelle Medizin, Institut für Experimentelle Endokrinologie, Department of Reproductive Biology, Institut für Biochemie und Molekularbiologie I, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany
Zentrum für Experimentelle Medizin, Institut für Experimentelle Endokrinologie, Department of Reproductive Biology, Institut für Biochemie und Molekularbiologie I, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany

Search for other papers by Joachim M Weitzel in
Google Scholar
PubMed Close

retinoid X receptor (RXR). The TR interacts with cofactors that mediate the T 3 signaling to the basal transcriptional machinery and activates or represses gene transcription ( Zhang & Lazar 2000 ). Gene expression analysis indicated that the majority of T

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-08-0023
Volume/Issue:
Volume 41: Issue 1
Free access
Pankaj Lamba Center for Biomedical Research, Population Council and The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

Search for other papers by Pankaj Lamba in
Google Scholar
PubMed Close
,
Michelle M Santos Center for Biomedical Research, Population Council and The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

Search for other papers by Michelle M Santos in
Google Scholar
PubMed Close
,
Daniel P Philips Center for Biomedical Research, Population Council and The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

Search for other papers by Daniel P Philips in
Google Scholar
PubMed Close
, and
Daniel J Bernard Center for Biomedical Research, Population Council and The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA

Search for other papers by Daniel J Bernard in
Google Scholar
PubMed Close

. Indeed, changes in hormonal milieu (e.g. declines in serum inhibins and intra-pituitary follistatins) following the primary surge provide a permissive environment for locally produced activins to rapidly stimulate increases in Fshb transcription and

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.01961
Volume/Issue:
Volume 36: Issue 1
Free access
Haruo Nogami Department of Neuroendocrinology, Institute of Basic Medical Sciences, University of Tsukuba, 1-1–1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan
Department of Anatomy, School of Medicine, Keio University, Tokyo 160-8582, Japan

Search for other papers by Haruo Nogami in
Google Scholar
PubMed Close
,
Yoshiki Hiraoka Department of Neuroendocrinology, Institute of Basic Medical Sciences, University of Tsukuba, 1-1–1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan
Department of Anatomy, School of Medicine, Keio University, Tokyo 160-8582, Japan

Search for other papers by Yoshiki Hiraoka in
Google Scholar
PubMed Close
,
Kiyomoto Ogasawara Department of Neuroendocrinology, Institute of Basic Medical Sciences, University of Tsukuba, 1-1–1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan
Department of Anatomy, School of Medicine, Keio University, Tokyo 160-8582, Japan

Search for other papers by Kiyomoto Ogasawara in
Google Scholar
PubMed Close
,
Sadakazu Aiso Department of Neuroendocrinology, Institute of Basic Medical Sciences, University of Tsukuba, 1-1–1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan
Department of Anatomy, School of Medicine, Keio University, Tokyo 160-8582, Japan

Search for other papers by Sadakazu Aiso in
Google Scholar
PubMed Close
, and
Setsuji Hisano Department of Neuroendocrinology, Institute of Basic Medical Sciences, University of Tsukuba, 1-1–1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan
Department of Anatomy, School of Medicine, Keio University, Tokyo 160-8582, Japan

Search for other papers by Setsuji Hisano in
Google Scholar
PubMed Close

-specific manner ( Truss & Beato 1993 ). Ligand-activated GRs bind to the specific DNA element, the glucocorticoid response element (GRE), to induce a transcription of the target gene ( Becker et al. 1986 ). Glucocorticoid responsive genes, in general, contain

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.01870
Volume/Issue:
Volume 35: Issue 3
Free access
Pui-Sin Man School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK

Search for other papers by Pui-Sin Man in
Google Scholar
PubMed Close
,
Timothy Wells School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK

Search for other papers by Timothy Wells in
Google Scholar
PubMed Close
, and
David A Carter School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK

Search for other papers by David A Carter in
Google Scholar
PubMed Close

important molecular regulator in the adult pituitary is the C2H2 zinc finger transcription factor, early growth response factor 1 (EGR1), that is expressed as a 75 kDa nuclear protein in the rat anterior pituitary ( Tremblay & Drouin 1999 , Wolfe & Call

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-14-0158
Volume/Issue:
Volume 53: Issue 2
Free access
Carlos Gaspar Secció de Bioquímica i Biologia Molecular, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l’Alimentació, Universitat de Barcelona, Barcelona, Spain

Search for other papers by Carlos Gaspar in
Google Scholar
PubMed Close
,
Jonás I Silva-Marrero Secció de Bioquímica i Biologia Molecular, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l’Alimentació, Universitat de Barcelona, Barcelona, Spain

Search for other papers by Jonás I Silva-Marrero in
Google Scholar
PubMed Close
,
María C Salgado Servei de Bioquímica Clínica, Hospital Sant Joan de Déu, Barcelona, Spain

Search for other papers by María C Salgado in
Google Scholar
PubMed Close
,
Isabel V Baanante Secció de Bioquímica i Biologia Molecular, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l’Alimentació, Universitat de Barcelona, Barcelona, Spain

Search for other papers by Isabel V Baanante in
Google Scholar
PubMed Close
, and
Isidoro Metón Secció de Bioquímica i Biologia Molecular, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l’Alimentació, Universitat de Barcelona, Barcelona, Spain

Search for other papers by Isidoro Metón in
Google Scholar
PubMed Close

( Figueiredo-Silva et al. 2010 ), while it increases in Oncorhynchus mykiss ( Moyano et al. 1991 ). Little is known about transcriptional regulation of Gdh expression in vertebrates. In silico analysis allowed detection of potential binding sites for

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-17-0142
Volume/Issue:
Volume 60: Issue 3
Free access
Lorraine J Gudas Department of Pharmacology, and Revlon Pharmaceutical Professor of Pharmacology and Toxicology, Pharmacology Department, Weill Cornell Medicine of Cornell University, and the Meyer Cancer Center of Weill Cornell Medicine, New York, New York, USA

Search for other papers by Lorraine J Gudas in
Google Scholar
PubMed Close

as either repressors or activators of gene transcription ( Fig. 1 ). They possess both a ligand binding domain and a DNA binding domain. The endogenously produced ligand, RA, induces a ‘molecular switch’ that involves changing the regulatory proteins

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-22-0082
Volume/Issue:
Volume 69: Issue 4
Free access
Dorka Nagy Department of Metabolism, Digestion and Reproduction, Section of Genetics and Genomics, Imperial College London, London, UK
National Heart and Lung Institute, Imperial College London, London, UK

Search for other papers by Dorka Nagy in
Google Scholar
PubMed Close
,
Hannah Maude Department of Metabolism, Digestion and Reproduction, Section of Genetics and Genomics, Imperial College London, London, UK

Search for other papers by Hannah Maude in
Google Scholar
PubMed Close
,
Graeme M Birdsey National Heart and Lung Institute, Imperial College London, London, UK

Search for other papers by Graeme M Birdsey in
Google Scholar
PubMed Close
,
Anna M Randi National Heart and Lung Institute, Imperial College London, London, UK

Search for other papers by Anna M Randi in
Google Scholar
PubMed Close
, and
Inês Cebola Department of Metabolism, Digestion and Reproduction, Section of Genetics and Genomics, Imperial College London, London, UK

Search for other papers by Inês Cebola in
Google Scholar
PubMed Close

tissue (~80% of its mass) has made it difficult to assess and analyse LSEC-specific aspects of gene expression, chromatin accessibility, and transcription factor (TF) occupancy using bulk liver tissue. With advances in cell isolation techniques and single

Article Type:
Review Article
Collections:
Rising Stars special collection
DOI:
https://doi.org/10.1530/JME-23-0026
Volume/Issue:
Volume 71: Issue 2
Open access
Susanne Arnold Faculty of Medicine, Institute for Neuroanatomy, RWTH Aachen University, 52074 Aachen, Germany

Search for other papers by Susanne Arnold in
Google Scholar
PubMed Close
,
Gilda Wright de Araújo Faculty of Medicine, Institute for Neuroanatomy, RWTH Aachen University, 52074 Aachen, Germany

Search for other papers by Gilda Wright de Araújo in
Google Scholar
PubMed Close
, and
Cordian Beyer Faculty of Medicine, Institute for Neuroanatomy, RWTH Aachen University, 52074 Aachen, Germany

Search for other papers by Cordian Beyer in
Google Scholar
PubMed Close

fission for neurodegeneration, we studied the effect of E and P on the transcription level of mitochondrial fusion and fission genes in cortical astrocytes in vitro . Astrocytes were chosen since they are the outstanding cell type in the CNS supporting

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-08-0085
Volume/Issue:
Volume 41: Issue 5
Free access
M C Salgado Departament de Bioquímica i Biologia Molecular, Facultat de Farmácia, Universitat de Barcelona, Diagonal 643, 08028 Barcelona, Spain

Search for other papers by M C Salgado in
Google Scholar
PubMed Close
,
I Metón Departament de Bioquímica i Biologia Molecular, Facultat de Farmácia, Universitat de Barcelona, Diagonal 643, 08028 Barcelona, Spain

Search for other papers by I Metón in
Google Scholar
PubMed Close
,
M Egea Departament de Bioquímica i Biologia Molecular, Facultat de Farmácia, Universitat de Barcelona, Diagonal 643, 08028 Barcelona, Spain

Search for other papers by M Egea in
Google Scholar
PubMed Close
, and
I V Baanante Departament de Bioquímica i Biologia Molecular, Facultat de Farmácia, Universitat de Barcelona, Diagonal 643, 08028 Barcelona, Spain

Search for other papers by I V Baanante in
Google Scholar
PubMed Close

HepG2 cells, repression of G6pc transcription by insulin requires two regions in the proximal promoter, designated A and B. Hepatocyte nuclear factor (HNF)-1 binds to region A, and enhances the effect of insulin ( Streeper et al. 1998 ). Recently

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.01552
Volume/Issue:
Volume 33: Issue 3
Free access
Talitha van der Meulen Department of Neurobiology, Department of Physiology and Membrane Biology, Physiology and Behavior, College of Biological Sciences

Search for other papers by Talitha van der Meulen in
Google Scholar
PubMed Close
and
Mark O Huising Department of Neurobiology, Department of Physiology and Membrane Biology, Physiology and Behavior, College of Biological Sciences
Department of Neurobiology, Department of Physiology and Membrane Biology, Physiology and Behavior, College of Biological Sciences

Search for other papers by Mark O Huising in
Google Scholar
PubMed Close

, Unger & Cherrington 2012 ). Despite their opposing roles in the maintenance of a dynamic equilibrium of blood glucose levels, α and β cells are derived from a common progenitor. They continue to share expression of many transcription factors and genes

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-14-0290
Volume/Issue:
Volume 54: Issue 2
Free access