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Carla A Piccinato Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil

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Helena Malvezzi Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil

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Douglas A Gibson MRC Centre for Inflammation Research, The University of Edinburgh, Edinburgh, UK

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Philippa T K Saunders MRC Centre for Inflammation Research, The University of Edinburgh, Edinburgh, UK

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-analysis of 11 genome-wide association case–control data sets, involving 17,045 endometriosis cases identified five new genetic loci (SNPs) significantly associated with endometriosis risk implicating genes involved in sex steroid hormone pathways that

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-17-0297
Volume/Issue:
Volume 61: Issue 2
Free access
Katherine A Leehy Department of Medicine and Pharmacology University of Minnesota Twin Cities Minneapolis, Minnesota, USA

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Tarah M Regan Anderson Department of Medicine and Pharmacology University of Minnesota Twin Cities Minneapolis, Minnesota, USA

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Andrea R Daniel Department of Medicine and Pharmacology University of Minnesota Twin Cities Minneapolis, Minnesota, USA

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Carol A Lange Department of Medicine and Pharmacology University of Minnesota Twin Cities Minneapolis, Minnesota, USA

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Julie H Ostrander Department of Medicine and Pharmacology University of Minnesota Twin Cities Minneapolis, Minnesota, USA

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Introduction Steroid hormone receptors (SRs) belong to the nuclear receptor superfamily of ligand-activated transcription factors. Members include the mineralocorticoid receptors, androgen receptors (ARs), estrogen receptors (ERs

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-15-0322
Volume/Issue:
Volume 56: Issue 3
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Fabiana Cornejo Maciel Department of Biochemistry, School of Medicine, University of Buenos Aires, Paraguay 2155, 5 th(C1121ABG) Buenos Aires, Argentina

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Paula Maloberti Department of Biochemistry, School of Medicine, University of Buenos Aires, Paraguay 2155, 5 th(C1121ABG) Buenos Aires, Argentina

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Isabel Neuman Department of Biochemistry, School of Medicine, University of Buenos Aires, Paraguay 2155, 5 th(C1121ABG) Buenos Aires, Argentina

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Florencia Cano Department of Biochemistry, School of Medicine, University of Buenos Aires, Paraguay 2155, 5 th(C1121ABG) Buenos Aires, Argentina

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Rocío Castilla Department of Biochemistry, School of Medicine, University of Buenos Aires, Paraguay 2155, 5 th(C1121ABG) Buenos Aires, Argentina

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Fernanda Castillo Department of Biochemistry, School of Medicine, University of Buenos Aires, Paraguay 2155, 5 th(C1121ABG) Buenos Aires, Argentina

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Cristina Paz Department of Biochemistry, School of Medicine, University of Buenos Aires, Paraguay 2155, 5 th(C1121ABG) Buenos Aires, Argentina

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Ernesto J Podestá Department of Biochemistry, School of Medicine, University of Buenos Aires, Paraguay 2155, 5 th(C1121ABG) Buenos Aires, Argentina

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arachidonoyl-CoA synthetases in intact cells ( Tomoda et al. 1987 , Hartman et al. 1989 ). We also showed that the hormonal regulation of steroid synthesis needs the concerted action of ACS4 and MTE-I ( Maloberti et al. 2002 ). In addition, it is also

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.01691
Volume/Issue:
Volume 34: Issue 3
Free access
James W Antoon Tulane Department of Pharmacology, Section of Hematology and Medical Oncology, Department of Pharmacy, Tulane Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL-83, New Orleans, Louisiana 70112, USA

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William D Meacham Tulane Department of Pharmacology, Section of Hematology and Medical Oncology, Department of Pharmacy, Tulane Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL-83, New Orleans, Louisiana 70112, USA

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Melyssa R Bratton Tulane Department of Pharmacology, Section of Hematology and Medical Oncology, Department of Pharmacy, Tulane Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL-83, New Orleans, Louisiana 70112, USA

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Evelyn M Slaughter Tulane Department of Pharmacology, Section of Hematology and Medical Oncology, Department of Pharmacy, Tulane Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL-83, New Orleans, Louisiana 70112, USA

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Lyndsay V Rhodes Tulane Department of Pharmacology, Section of Hematology and Medical Oncology, Department of Pharmacy, Tulane Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL-83, New Orleans, Louisiana 70112, USA

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Hasina B Ashe Tulane Department of Pharmacology, Section of Hematology and Medical Oncology, Department of Pharmacy, Tulane Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL-83, New Orleans, Louisiana 70112, USA

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Thomas E Wiese Tulane Department of Pharmacology, Section of Hematology and Medical Oncology, Department of Pharmacy, Tulane Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL-83, New Orleans, Louisiana 70112, USA

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Matthew E Burow Tulane Department of Pharmacology, Section of Hematology and Medical Oncology, Department of Pharmacy, Tulane Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL-83, New Orleans, Louisiana 70112, USA

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Barbara S Beckman Tulane Department of Pharmacology, Section of Hematology and Medical Oncology, Department of Pharmacy, Tulane Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL-83, New Orleans, Louisiana 70112, USA

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steroid hormone biosynthesis . Sub-Cellular Biochemistry 49 387 – 412 . doi:10.1007/978-1-4020-8831-5_15 . Meacham WD Antoon JW Burow ME Struckhoff AP Beckman BS 2009 Sphingolipids as determinants of apoptosis and chemoresistance in the

Article Type:
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DOI:
https://doi.org/10.1530/JME-10-0116
Volume/Issue:
Volume 46: Issue 3
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Daniel Patiño-García Departamento de Fisiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile (PUC), Santiago, Chile
Departamento de Ciencias Químicas y Biológicas, Universidad Bernardo O’Higgins, Facultad de Salud, Santiago, Chile

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Leonor Cruz-Fernandes Departamento de Fisiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile (PUC), Santiago, Chile

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Julio Buñay Departamento de Fisiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile (PUC), Santiago, Chile

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Renán Orellana Departamento de Ciencias Químicas y Biológicas, Universidad Bernardo O’Higgins, Facultad de Salud, Santiago, Chile

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Ricardo D Moreno Departamento de Fisiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile (PUC), Santiago, Chile

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vivo murine studies have shown that single and/or mixed exposure to phthalates or alkylphenols influences the development of ovarian follicles and changes gene expression associated with the regulation and synthesis of steroid hormones as well as

Article Type:
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DOI:
https://doi.org/10.1530/JME-20-0149
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Volume 65: Issue 4
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Inna Astapova Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA

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the first co-activators, such as steroid receptor co-activators 1–3 (SRC1–3, also known as NCOA1–3) and co-repressors: nuclear receptor co-repressor (NCoR or NCOR1) and silencing mediator of retinoic acid receptor and thyroid hormone receptor (SMRT or

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-15-0246
Volume/Issue:
Volume 56: Issue 3
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Seung Chul Kim Department of Obstetrics and Gynecology, Biomedical Research Institute, Pusan National University School of Medicine, Busan, Republic of Korea

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Mee-Na Park Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Republic of Korea

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Young Joo Lee Department of Obstetrics and Gynecology, Biomedical Research Institute, Pusan National University School of Medicine, Busan, Republic of Korea

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Jong Kil Joo Department of Obstetrics and Gynecology, Biomedical Research Institute, Pusan National University School of Medicine, Busan, Republic of Korea

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Beum-Soo An Department of Biomaterials Science, College of Natural Resources & Life Science/Life and Industry Convergence Research Institute, Pusan National University, Republic of Korea

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tissue-specific expression patterns ( Mueller & Korach 2001 ). ERα and ERβ are nuclear steroid hormone receptors with similarities in terms of ligand-binding and nuclear DNA-binding regions ( Arnal et al. 2007 , Luksha & Kublickiene 2009 ). ERα and ERβ

Article Type:
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DOI:
https://doi.org/10.1530/JME-15-0248
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Volume 56: Issue 3
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Lu Wang Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China

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Wen He Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China

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Xiaoyu Xu Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China

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Lingbin Qi Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China

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Bo Lv Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China

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Jiaying Qin Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China

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Zhigang Xue Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China
Reproductive Medicine Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Orthopaedic Department of Tongji Hospital, School of Medicine, Tongji University, Shanghai, China

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Jinfeng Xue Department of Regenerative Medicine, Tongji University School of Medicine, Shanghai, China

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shared similar biological processes, including steroid hormone-related terms (responses to E2 processes, response to estrogen processes, and response to steroid hormone processes) and oxidative stress-related terms (response to ROS, response to H 2 O 2

Article Type:
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DOI:
https://doi.org/10.1530/JME-21-0095
Volume/Issue:
Volume 67: Issue 3
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S Hombach-Klonisch Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada
Department of Immunology, Martin Luther University, Halle-Wittenberg, Germany
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, UK
Department of Anatomy, RWTH Aachen, Germany
Department of Dermatology, RWTH Aachen, Germany
Department of Analytical and Environmental Chemistry, Martin Luther University, Halle-Wittenberg, Germany
Department of Pathology, Martin Luther University, Halle-Wittenberg, Germany

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A Kehlen Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada
Department of Immunology, Martin Luther University, Halle-Wittenberg, Germany
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, UK
Department of Anatomy, RWTH Aachen, Germany
Department of Dermatology, RWTH Aachen, Germany
Department of Analytical and Environmental Chemistry, Martin Luther University, Halle-Wittenberg, Germany
Department of Pathology, Martin Luther University, Halle-Wittenberg, Germany

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P A Fowler Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada
Department of Immunology, Martin Luther University, Halle-Wittenberg, Germany
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, UK
Department of Anatomy, RWTH Aachen, Germany
Department of Dermatology, RWTH Aachen, Germany
Department of Analytical and Environmental Chemistry, Martin Luther University, Halle-Wittenberg, Germany
Department of Pathology, Martin Luther University, Halle-Wittenberg, Germany

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B Huppertz Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada
Department of Immunology, Martin Luther University, Halle-Wittenberg, Germany
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, UK
Department of Anatomy, RWTH Aachen, Germany
Department of Dermatology, RWTH Aachen, Germany
Department of Analytical and Environmental Chemistry, Martin Luther University, Halle-Wittenberg, Germany
Department of Pathology, Martin Luther University, Halle-Wittenberg, Germany

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J F Jugert Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada
Department of Immunology, Martin Luther University, Halle-Wittenberg, Germany
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, UK
Department of Anatomy, RWTH Aachen, Germany
Department of Dermatology, RWTH Aachen, Germany
Department of Analytical and Environmental Chemistry, Martin Luther University, Halle-Wittenberg, Germany
Department of Pathology, Martin Luther University, Halle-Wittenberg, Germany

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G Bischoff Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada
Department of Immunology, Martin Luther University, Halle-Wittenberg, Germany
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, UK
Department of Anatomy, RWTH Aachen, Germany
Department of Dermatology, RWTH Aachen, Germany
Department of Analytical and Environmental Chemistry, Martin Luther University, Halle-Wittenberg, Germany
Department of Pathology, Martin Luther University, Halle-Wittenberg, Germany

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E Schlüter Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada
Department of Immunology, Martin Luther University, Halle-Wittenberg, Germany
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, UK
Department of Anatomy, RWTH Aachen, Germany
Department of Dermatology, RWTH Aachen, Germany
Department of Analytical and Environmental Chemistry, Martin Luther University, Halle-Wittenberg, Germany
Department of Pathology, Martin Luther University, Halle-Wittenberg, Germany

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J Buchmann Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada
Department of Immunology, Martin Luther University, Halle-Wittenberg, Germany
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, UK
Department of Anatomy, RWTH Aachen, Germany
Department of Dermatology, RWTH Aachen, Germany
Department of Analytical and Environmental Chemistry, Martin Luther University, Halle-Wittenberg, Germany
Department of Pathology, Martin Luther University, Halle-Wittenberg, Germany

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T Klonisch Department of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada
Department of Immunology, Martin Luther University, Halle-Wittenberg, Germany
Department of Obstetrics and Gynecology, University of Aberdeen, Aberdeen, UK
Department of Anatomy, RWTH Aachen, Germany
Department of Dermatology, RWTH Aachen, Germany
Department of Analytical and Environmental Chemistry, Martin Luther University, Halle-Wittenberg, Germany
Department of Pathology, Martin Luther University, Halle-Wittenberg, Germany

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Introduction The monthly recurrent remodeling of the human endometrium in preparation for embryonic implantation is under the control of the ovarian steroid hormones estrogen and progesterone (P4), which profoundly affect

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.01550
Volume/Issue:
Volume 34: Issue 2
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Dominique H Eghlidi Department of Neurology and Division of Sleep Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

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Vasilios T Garyfallou Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA

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Steven G Kohama Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA

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Henryk F Urbanski Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA
Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon, USA
Department of Physiology & Pharmacology, Oregon Health & Science University, Portland, Oregon, USA

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. 2010 , Eghlidi & Urbanski 2015 ). Although age-related hormone changes also occur in males, the decrease in circulating sex-steroid concentrations is more gradual and less complete than that in females ( Bremner et al. 1983 , Down & Urbanski 2006

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-17-0094
Volume/Issue:
Volume 59: Issue 2
Free access