Filter

Refine by collections

Refine by access

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 21 - 30 of 640 items for :

  • steroid hormones x
  • Refine by access: All content x
Clear All
S Kerkhofs Molecular Endocrinology Laboratory, Department of Molecular Cell Biology, University of Leuven, Campus Gasthuisberg O&N1, PO Box 901, Herestraat 49, BE-3000 Leuven, Belgium

Search for other papers by S Kerkhofs in
Google Scholar
PubMed Close
,
S Denayer Molecular Endocrinology Laboratory, Department of Molecular Cell Biology, University of Leuven, Campus Gasthuisberg O&N1, PO Box 901, Herestraat 49, BE-3000 Leuven, Belgium

Search for other papers by S Denayer in
Google Scholar
PubMed Close
,
A Haelens Molecular Endocrinology Laboratory, Department of Molecular Cell Biology, University of Leuven, Campus Gasthuisberg O&N1, PO Box 901, Herestraat 49, BE-3000 Leuven, Belgium

Search for other papers by A Haelens in
Google Scholar
PubMed Close
, and
F Claessens Molecular Endocrinology Laboratory, Department of Molecular Cell Biology, University of Leuven, Campus Gasthuisberg O&N1, PO Box 901, Herestraat 49, BE-3000 Leuven, Belgium

Search for other papers by F Claessens in
Google Scholar
PubMed Close

Introduction Androgens are steroid hormones, which play an important role in the development and maintenance of male characteristics. The two most important androgens are testosterone and 5α-dihydrotestosterone (DHT). Each of them plays a distinct

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-08-0122
Volume/Issue:
Volume 42: Issue 1
Free access
Shannon E Mullican Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, and The Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA

Search for other papers by Shannon E Mullican in
Google Scholar
PubMed Close
,
Joanna R DiSpirito Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, and The Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA

Search for other papers by Joanna R DiSpirito in
Google Scholar
PubMed Close
, and
Mitchell A Lazar Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, and The Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA

Search for other papers by Mitchell A Lazar in
Google Scholar
PubMed Close

Introduction In the late 1980s the observation that the steroid hormone receptors shared highly conserved domains encouraged researchers to search for additional members of the nuclear receptor (NR) family ( Mangelsdorf et al . 1995 , Giguère 1999

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-13-0212
Volume/Issue:
Volume 51: Issue 3
Free access
M Hołysz Department of Biochemistry and Molecular Biology, Poznan University of Medical Sciences, 6 Swiecickiego St., 60-781 Poznan, Poland

Search for other papers by M Hołysz in
Google Scholar
PubMed Close
,
N Derebecka-Hołysz Department of Biochemistry and Molecular Biology, Poznan University of Medical Sciences, 6 Swiecickiego St., 60-781 Poznan, Poland

Search for other papers by N Derebecka-Hołysz in
Google Scholar
PubMed Close
, and
W H Trzeciak Department of Biochemistry and Molecular Biology, Poznan University of Medical Sciences, 6 Swiecickiego St., 60-781 Poznan, Poland

Search for other papers by W H Trzeciak in
Google Scholar
PubMed Close

Introduction Steroid hormone synthesis in the adrenal cortex requires a continuous supply of free cholesterol. However, endogenous synthesis provides only about 20% of the cholesterol required for corticosteroid formation ( Kraemer 2007 ), the main

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-10-0035
Volume/Issue:
Volume 46: Issue 1
Free access
Robin Haring Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Robin Haring in
Google Scholar
PubMed Close
,
Henri Wallaschofski Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Henri Wallaschofski in
Google Scholar
PubMed Close
,
Alexander Teumer Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Alexander Teumer in
Google Scholar
PubMed Close
,
Heyo Kroemer Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Heyo Kroemer in
Google Scholar
PubMed Close
,
Angela E Taylor Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Angela E Taylor in
Google Scholar
PubMed Close
,
Cedric H L Shackleton Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Cedric H L Shackleton in
Google Scholar
PubMed Close
,
Matthias Nauck Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Matthias Nauck in
Google Scholar
PubMed Close
,
Uwe Völker Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Uwe Völker in
Google Scholar
PubMed Close
,
Georg Homuth Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Georg Homuth in
Google Scholar
PubMed Close
, and
Wiebke Arlt Institute of Clinical Chemistry and Laboratory Medicine, Interfaculty Institute for Genetics and Functional Genomics, Department of Pharmacology, School of Clinical and Experimental Medicine

Search for other papers by Wiebke Arlt in
Google Scholar
PubMed Close

Introduction DHEAS is the most abundant steroid in human circulation and represents the conjugated, nonactive excretion form of DHEA, which acts as the universal sex steroid precursor and the major source of androgens in women ( Arlt et al . 1999

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-12-0185
Volume/Issue:
Volume 50: Issue 1
Open access
View license
J J Brosens Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London W12 ONN, United Kingdom
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

Search for other papers by J J Brosens in
Google Scholar
PubMed Close
and
B Gellersen Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London W12 ONN, United Kingdom
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

Search for other papers by B Gellersen in
Google Scholar
PubMed Close

with multiple club-shaped projections arising from their cell surface ( Wynn 1974 ). In pregnancy, the endometrium is under the continued support of steroid hormones as well as blastocyst-derived signals such as human chorionic gonadotrophin (hCG). This

Article Type:
Review Article
DOI:
https://doi.org/10.1677/jme.1.02060
Volume/Issue:
Volume 36: Issue 3
Free access
Junhui Zhang
Search for other papers by Junhui Zhang in
Google Scholar
PubMed Close
,
Francis T F Tsai
Search for other papers by Francis T F Tsai in
Google Scholar
PubMed Close
, and
David S Geller
Search for other papers by David S Geller in
Google Scholar
PubMed Close

Introduction Steroid hormones, including androgens, progestins, estrogens, glucocorticoids, and mineralocorticoids, regulate a wide variety of physiological processes by binding to their cognate receptors and are integral to

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.02089
Volume/Issue:
Volume 37: Issue 1
Free access
Andrea Weckman
Search for other papers by Andrea Weckman in
Google Scholar
PubMed Close
,
Antonio Di Ieva
Search for other papers by Antonio Di Ieva in
Google Scholar
PubMed Close
,
Fabio Rotondo Division of Neurosurgery, Division of Pathology, Department of Neurosurgery, Division of Neurooncology, Department of Surgery, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada

Search for other papers by Fabio Rotondo in
Google Scholar
PubMed Close
,
Luis V Syro Division of Neurosurgery, Division of Pathology, Department of Neurosurgery, Division of Neurooncology, Department of Surgery, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada

Search for other papers by Luis V Syro in
Google Scholar
PubMed Close
,
Leon D Ortiz Division of Neurosurgery, Division of Pathology, Department of Neurosurgery, Division of Neurooncology, Department of Surgery, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada

Search for other papers by Leon D Ortiz in
Google Scholar
PubMed Close
,
Kalman Kovacs Division of Neurosurgery, Division of Pathology, Department of Neurosurgery, Division of Neurooncology, Department of Surgery, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada

Search for other papers by Kalman Kovacs in
Google Scholar
PubMed Close
, and
Michael D Cusimano
Search for other papers by Michael D Cusimano in
Google Scholar
PubMed Close

direct fusion of secretory granules with lysosomes; 2) as steroids are not stored in secretory granules, in steroid-secreting endocrine cells, crinophagy does not exist and macroautophagy is the predominant control mechanism of intracellular hormone

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-13-0241
Volume/Issue:
Volume 52: Issue 2
Free access
Alexander V Sirotkin Institute of Genetics and Reproduction, Constantine the Philosopher University, Altogen Biosystems, Polyclinics and Hospital of Nitra, Animal Production Research Centre, Hlohovecká 2, 951 41 Lužianky near Nitra, Slovakia
Institute of Genetics and Reproduction, Constantine the Philosopher University, Altogen Biosystems, Polyclinics and Hospital of Nitra, Animal Production Research Centre, Hlohovecká 2, 951 41 Lužianky near Nitra, Slovakia

Search for other papers by Alexander V Sirotkin in
Google Scholar
PubMed Close
,
Dmitriy Ovcharenko Institute of Genetics and Reproduction, Constantine the Philosopher University, Altogen Biosystems, Polyclinics and Hospital of Nitra, Animal Production Research Centre, Hlohovecká 2, 951 41 Lužianky near Nitra, Slovakia

Search for other papers by Dmitriy Ovcharenko in
Google Scholar
PubMed Close
, and
Milos Mlyncek Institute of Genetics and Reproduction, Constantine the Philosopher University, Altogen Biosystems, Polyclinics and Hospital of Nitra, Animal Production Research Centre, Hlohovecká 2, 951 41 Lužianky near Nitra, Slovakia

Search for other papers by Milos Mlyncek in
Google Scholar
PubMed Close

. 2007 , Sawada et al . 2007 , Wang & Tsang 2007 ). The most well-characterized ovarian hormones include steroids, especially progesterone (P 4 ), and peptide insulin-like growth factor-1 (IGF1). These hormones control a wide array of reproductive

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-08-0179
Volume/Issue:
Volume 44: Issue 1
Free access
J J Allen Department of Biomedical Sciences, Cornell University, Ithaca, New York, USA

Search for other papers by J J Allen in
Google Scholar
PubMed Close
,
S L Herrick Department of Biomedical Sciences, Cornell University, Ithaca, New York, USA

Search for other papers by S L Herrick in
Google Scholar
PubMed Close
, and
J E Fortune Department of Biomedical Sciences, Cornell University, Ithaca, New York, USA

Search for other papers by J E Fortune in
Google Scholar
PubMed Close

about the mechanisms that regulate steroidogenesis during fetal life, particularly at this critical time of development. In adult mammalian ovaries, the production of sex steroids from cholesterol is regulated by the gonadotropins, luteinizing hormone

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-16-0152
Volume/Issue:
Volume 57: Issue 4
Free access
Gerald Thiel Department of Medical Biochemistry and Molecular Biology, University of Saarland Medical Center, Building 44, D-66421 Homburg, Germany

Search for other papers by Gerald Thiel in
Google Scholar
PubMed Close
,
Isabelle Müller Department of Medical Biochemistry and Molecular Biology, University of Saarland Medical Center, Building 44, D-66421 Homburg, Germany

Search for other papers by Isabelle Müller in
Google Scholar
PubMed Close
, and
Oliver G Rössler Department of Medical Biochemistry and Molecular Biology, University of Saarland Medical Center, Building 44, D-66421 Homburg, Germany

Search for other papers by Oliver G Rössler in
Google Scholar
PubMed Close

stimulates TRPM3 channel activity is the basis for the hypothesis that TRPM3 functions as an ionotropic steroid receptor of pancreatic β-cells linking insulin release with steroid hormone signaling ( Frühwald et al . 2012 ). Pregnenolone sulfate: a ligand

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JME-12-0237
Volume/Issue:
Volume 50: Issue 3
Free access